Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elizabeth A. Maull"'
Autor:
Deepak Mav, Ruchir R Shah, Brian E Howard, Scott S Auerbach, Pierre R Bushel, Jennifer B Collins, David L Gerhold, Richard S Judson, Agnes L Karmaus, Elizabeth A Maull, Donna L Mendrick, B Alex Merrick, Nisha S Sipes, Daniel Svoboda, Richard S Paules
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191105 (2018)
Changes in gene expression can help reveal the mechanisms of disease processes and the mode of action for toxicities and adverse effects on cellular responses induced by exposures to chemicals, drugs and environment agents. The U.S. Tox21 Federal col
Externí odkaz:
https://doaj.org/article/ac4c3100313c431db2f048cc682fb4c1
Autor:
Amy Zmarowski, Robert L. Tanguay, Tamara Tal, Matt D. Stout, Antonio Planchart, Nigel J. Walker, Edward J. Perkins, Elizabeth A. Maull, Mitch S Wilbanks, David Allen, Stephanie Padilla, J Hamm, Greg Baker, Donald B. Stedman, Patricia Ceger, David C. Volz
Publikováno v:
ALTEX. 36:103-120
There is a need for fast, efficient, and cost-effective hazard identification and characterization of chemical hazards. This need is generating increased interest in the use of zebrafish embryos as both a screening tool and an alternative to mammalia
Autor:
Donna L. Mendrick, Elizabeth A. Maull, J. Craig Rowlands, David Allen, Stephen W. Edwards, Warren Casey, Michelle R. Embry, Joanna Matheson, Kristie Sullivan, Nicole Kleinstreuer, Sharon Munn
Publikováno v:
Regulatory Toxicology and Pharmacology. 76:39-50
An adverse outcome pathway (AOP) helps to organize existing knowledge on chemical mode of action, starting with a molecular initiating event such as receptor binding, continuing through key events, and ending with an adverse outcome such as reproduct
Autor:
Warren Casey, Andy Shapiro, Arpit Tandon, Jason Phillips, Alexander Sedykh, Nicole Kleinstreuer, David Allen, Shannon M. Bell, Stephen Q. Morefield, Catherine S. Sprankle, Ruchir R. Shah, Elizabeth A. Maull
Publikováno v:
Environmental Health Perspectives
SUMMARY: Access to high-quality reference data is essential for the development, validation, and implementation of in vitro and in silico approaches that reduce and replace the use of animals in toxicity testing. Currently, these data must often be p
Autor:
Andre Kleensang, Miyoung Yoon, Michael L. Bittner, Scott S. Auerbach, Florian Martin, Sonia Grego, Edward R. Dougherty, Michael N J Liebman, Guilin Gary Qiao, Timothy R. Fennell, Elizabeth A. Maull, Philip C. Cooley, Ajit Dash, Susan Sumner, Sreenivasa Ramaiahgari, Francis J. Alexander, Jason Paragas, Brian T. Hawkins, Stephen S. Ferguson, Warren Casey, Anthony J. Hickey, Brian R. Berridge
Publikováno v:
ALTEX. 34(2)
Translating in vitro biological data into actionable information related to human health holds the potential to improve disease treatment and risk assessment of chemical exposures. While genomics has identified regulatory pathways at the cellular lev
Autor:
Joshua R. Edwards, Jingbo Pi, Chin-Hsiao Tseng, Dana Loomis, Habibul Ahsan, Kristina A. Thayer, Matthew P. Longnecker, Ellen K. Silbergeld, Elizabeth A. Maull, Ana Navas-Acien, Miroslav Styblo
Publikováno v:
Environmental Health Perspectives
Background: Diabetes affects an estimated 346 million persons globally, and total deaths from diabetes are projected to increase > 50% in the next decade. Understanding the role of environmental chemicals in the development or progression of diabetes
Autor:
Elizabeth A. Maull, Richard S. Paules, Brian E. Howard, David Gerhold, B. Alex Merrick, Jennifer B. Collins, Deepak Mav, Agnes L. Karmaus, Ruchir R. Shah, Pierre R. Bushel, Donna L. Mendrick, Scott S. Auerbach, Nisha S. Sipes, Daniel L. Svoboda, Richard S. Judson
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191105 (2018)
PLoS ONE
PLoS ONE
Changes in gene expression can help reveal the mechanisms of disease processes and the mode of action for toxicities and adverse effects on cellular responses induced by exposures to chemicals, drugs and environment agents. The U.S. Tox21 Federal col
Publikováno v:
Human and Ecological Risk Assessment: An International Journal. 7:687-716
This manuscript has been reviewed in accordance with the policy of the National Health and Environmental Effects Research Laboratory, U.S. Environmental Protection Agency, and approved for publication. Approval does not signify that the contents nece
Publikováno v:
Toxic Substance Mechanisms. 17:153-169
Trichloroethylene (TRI) is a volatile, mobile, clear, colorless liquid that has been widely used in industry as a solvent and cleaner and has become a major groundwater contaminant. TRI is a well-recognized animal carcinogen, exhibiting marked sex- a
Publikováno v:
Environmental Health Perspectives. 121
The goal of the National Toxicology Program (NTP) workshop review was to comprehensively evaluate the association between arsenic and diabetes, including epidemiologic and experimental evidence (Maull et al. 2012). Members of the arsenic breakout gro