Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Elizabeth A. Lipscomb"'
Autor:
Bennard van Ravenzwaay, Brandy Riffle, Carl Andre, R. Buesen, Heike Marxfeld, Jordan B. Sottosanto, Volker Strauss, Christine Wandelt, Elizabeth A. Lipscomb
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 124
The omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are recognized for their health-promoting qualities. Marine fish and fish oil currently provide the main sources of EPA and DHA f
Autor:
David Allen, Dorothea Sesardic, Michael P. Schmitt, Yoshinobu Horiuchi, Paul Stickings, Johan Descamps, Warren Casey, Daniela Verthelyi, Richard Isbrucker, Elizabeth A. Lipscomb, Nelson W Johnson, Juan Arciniega, Richard McFarland, Theresa M. Finn
Publikováno v:
Procedia in Vaccinology
NICEATM and ICCVAM convened an international workshop to review the state of the science of human and veterinary vaccine potency and safety testing methods, and to identify opportunities to advance new and improved methods that can further reduce, re
Autor:
Laura Privalle, Gustavo Julio Mello Monteiro de Lima, Xiaoyun He, Paulo Antonio Rabenschlag de Brum, Daniela Contri, C. H. Klein, Cui Zhou, Cuiyan Wang, Kunlun Huang, Jing Lu, Andreia Nakatani, Amechi Chukwudebe, Yanqing Wang, Valdir Silveira de Avila, Andrew Reed, Elizabeth A. Lipscomb
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 88
The safety and nutritional properties of CV127 soybeans were evaluated in rat and broiler feeding studies. Some episodic differences were observed between rats fed CV127, Conquista, and the standard diet for the endpoints examined. None of these diff
Publikováno v:
Cancer Research. 66:2732-2739
ErbB2 (HER2, Neu) and Ras play key roles in tumor invasion and metastasis. We identified a novel mechanism by which integrin alpha(6)beta(4) regulates ErbB2 expression, Ras activation, and the invasion of breast carcinoma cells. Here we show that int
Autor:
Aisling S. Dugan, Kaylene J. Simpson, Jennifer E. Ring, Arthur M. Mercurio, Stephen Lyle, Elizabeth A. Lipscomb
Publikováno v:
Cancer Research. 65:10970-10976
The alpha6beta4 integrin has been widely implicated in carcinoma function in vitro; however, in vivo data are scarce. To determine the importance of alpha6beta4 in tumor progression, a SUM-159 breast carcinoma cell line that is essentially devoid of
Publikováno v:
Journal of Biological Chemistry. 279:32287-32293
It has been proposed that a constitutive, physical association of the Met receptor and the alpha(6)beta(4) integrin exists on the surface of invasive carcinoma cells and that hepatocyte growth factor (HGF)-mediated invasion is dependent on alpha(6)be
Publikováno v:
Journal of Neurochemistry. 85:318-328
Sympathetic neurons deprived of nerve growth factor (NGF) release cytochrome c into the cytosol and undergo caspase-dependent cell death through a process that requires de novo gene expression. Expression of the SM-20 gene increases after NGF withdra
Publikováno v:
Clinical and Experimental Metastasis. 20:569-576
The application of small interfering RNA (siRNA) oligonucleotides to silence gene expression has profound implications for the intervention of human diseases including cancer. Using this technique, we explored the possibility that the α6β4 integrin
Publikováno v:
Journal of Neurochemistry. 73:429-432
Sympathetic neurons undergo apoptosis when deprived of nerve growth factor (NGF). Inhibitors of RNA or protein synthesis block this death, suggesting that gene expression is important for apoptosis in this system. We have identified SM-20 as a new ge
Publikováno v:
The Journal of Cell Biology
We define a novel mechanism by which integrins regulate growth factor expression and the survival of carcinoma cells. Specifically, we demonstrate that the alpha 6 beta 4 integrin enhances vascular endothelial growth factor (VEGF) translation in brea