Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Elizabeth A. Koch"'
Autor:
Elizabeth N. Koch, Catherine Ross, Bryan Joseph San Luis, Brenda J. Andrews, Michael Costanzo, Carles Pons, Chad L. Myers, Benjamin VanderSluis, Vincent Messier, Patrick Aloy, Matej Usaj, Charles Boone, Emira Shuteriqi, Mahfuzur Rahman, Justin Nelson, Wen Wang, Jing Hou
Publikováno v:
Science
Environmental impacts on gene networks A phenotype can be affected by genes interacting with other genes, the environment, or both other genes and the environment (a differential interaction). To better understand how these interactions function in y
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba40cb2b299076333691f88ae0666239
https://doi.org/10.1126/science.abf8424
https://doi.org/10.1126/science.abf8424
Autor:
Hai Dang Nguyen, Jordan Becker, Yee Mon Thu, Michael Costanzo, Elizabeth N Koch, Stephanie Smith, Kyungjae Myung, Chad L Myers, Charles Boone, Anja-Katrin Bielinsky
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
Deficiency in DNA ligase I, encoded by CDC9 in budding yeast, leads to the accumulation of unligated Okazaki fragments and triggers PCNA ubiquitination at a non-canonical lysine residue. This signal is crucial to activate the S phase checkpoint, whic
Externí odkaz:
https://doaj.org/article/d9ebedc3127d48b08e380a9f2aab0eae
Autor:
Alan M. Moses, Elena Kuzmin, Michael Pryszlak, Anton Khmelinskii, Matej Usaj, Jolanda van Leeuwen, Alex N. Nguyen Ba, Michael Costanzo, Brenda J. Andrews, Michael Knop, Wen Wang, Oren Kraus, Charles Boone, Brenda Varriano, Elizabeth N. Koch, Benjamin VanderSluis, Chad L. Myers, Mojca Mattiazzi Usaj, Ming Che Hu, Amy Tresenrider
Publikováno v:
Science
The fate of genes after duplication Gene duplication within an organism is a relatively common event during evolution. However, we cannot predict the fate of the duplicated genes: Will they be lost, evolve, or overlap in function within an organismal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee68547824fb20d421995e4fa669822
https://pubmed.ncbi.nlm.nih.gov/32587005
https://pubmed.ncbi.nlm.nih.gov/32587005
Publikováno v:
CrystEngComm. 19:5679-5685
Nucleic acids have been recognized as an important class of biomolecules for over half a century and are an integral component of many modern pharmaceuticals. Elucidating the associations between DNA nucleobases (thymine, cytosine, adenine and guanin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2da1599da169cc83fd9471941f9b7cf5
https://doi.org/10.1039/c7ce01347g
https://doi.org/10.1039/c7ce01347g
Autor:
Cameron Mohammadi, Marina A. Solomos, Rochelle Osborne, Jennifer A. Swift, Elizabeth S. Koch, Jessica H. Urbelis, Claire C. Usala
Publikováno v:
Crystal Growth & Design. 15:5068-5074
Diarylureas frequently assemble into structures with one-dimensional H-bonded chain motifs. Herein, we examine the ability of triphenylphosphine oxide (TPPO) to disrupt the H-bonding motif in 14 different meta-substituted N,N′-diphenylureas (mXPU)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9777d4836b2704a39dcabfb4f5a102b
https://doi.org/10.1021/acs.cgd.5b01039
https://doi.org/10.1021/acs.cgd.5b01039
Autor:
Carles Pons, Julia Hanchard, Hongwei Zhu, Daniel I. Bolnick, Brenda J. Andrews, Bryan Joseph San Luis, Elena Kuzmin, Matej Usaj, Michael Costanzo, Robbie Loewith, Wen Wang, Kaicong Xu, Amy A. Caudy, Michael Pryszlak, Chad L. Myers, Sara Sharifpoor, Yiqun Chen, Elizabeth N. Koch, Andrius J. Dagilis, Nydia Van Dyk, Benjamin VanderSluis, Margot Riggi, Guihong Tan, Ermira Shuteriqi, Mojca Mattiazzi Usaj, Raamesh Deshpande, Hamed Heydari, Attila Balint, Jason Zi Yang Wang, Charles Boone, Jolanda van Leeuwen, Grant W. Brown
Publikováno v:
Science (New York, N.Y.). 360(6386)
INTRODUCTION Genetic interactions occur when mutations in different genes combine to result in a phenotype that is different from expectation based on those of the individual mutations. Negative genetic interactions occur when a combination of mutati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cba155df06ecbf9111ed4cbb11edbff
https://pubmed.ncbi.nlm.nih.gov/29967502
https://pubmed.ncbi.nlm.nih.gov/29967502
Autor:
Charles Boone, Elizabeth N. Koch, Michael Costanzo, Brenda J. Andrews, Chad L. Myers, Raamesh Deshpande
SummaryModular structures in biological networks are ubiquitous and well-described, yet this organization does not capture the complexity of genes individually influencing many modules. Pleiotropy, the phenomenon of a single genetic locus with multip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc367ed094c03f64947b04a24bd8f3e
https://doi.org/10.1101/112326
https://doi.org/10.1101/112326
Autor:
Brian Luke, Marco Graf, Matej Usaj, Elizabeth N. Koch, Adrian J. Verster, Tina L. Sing, Dogus Murat Altintas, Zhaolei Zhang, Brenda J. Andrews, Virginie Ribaud, Michael Costanzo, Jacques Rougemont, Charles Boone, David Shore, Grant W. Brown, Robi D. Mitra, Erin B. Styles, Cyril Ribeyre, Daniele Novarina, Marco Muzi-Falconi, Lee Zamparo, Karen Founk, David Mayhew, Chad L. Myers
Publikováno v:
Cell Systems
Cell Systems, Elsevier, 2016, 3 (3), pp.264-277.e10. ⟨10.1016/j.cels.2016.08.008⟩
Cell Systems, Elsevier, 2016, 3 (3), pp.264-277.e10. ⟨10.1016/j.cels.2016.08.008⟩
A significant challenge of functional genomics is to develop methods for genome-scale acquisition and analysis of cell biological data. Here, we present an integrated method that combines genome-wide genetic perturbation of Saccharomyces cerevisiae w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9622aed18817de32a8bdbc7b62dd25c4
https://hal.archives-ouvertes.fr/hal-02553038
https://hal.archives-ouvertes.fr/hal-02553038
Publikováno v:
Perspectives on psychological science : a journal of the Association for Psychological Science. 6(1)
Like many topics of psychological research, the explanation for friendship is at once intuitive and difficult to address empirically. These difficulties worsen when one seeks, as we do, to go beyond “obvious” explanations (“humans are social cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e142c0f32958e872c84f0a85c383fa1
https://pubmed.ncbi.nlm.nih.gov/26162107
https://pubmed.ncbi.nlm.nih.gov/26162107
Autor:
Charles Boone, Haing Da Nguyen, Anja Katrin Bielinsky, Michael Costanzo, Elizabeth N. Koch, Jordan R. Becker, Yee Mon Thu, Kyungjae Myung, Stephanie Smith, Chad L. Myers
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
PLoS ONE, Vol 8, Iss 6, p e66379 (2013)
Deficiency in DNA ligase I, encoded by CDC9 in budding yeast, leads to the accumulation of unligated Okazaki fragments and triggers PCNA ubiquitination at a non-canonical lysine residue. This signal is crucial to activate the S phase checkpoint, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6effe0307d9958bac1c4f6d40e11fc99
http://europepmc.org/articles/PMC3688925
http://europepmc.org/articles/PMC3688925