Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Elizabeth A. Guthrie"'
Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication
Autor:
Merlin L. Robb, Xian Chen, Carolina Garrido, Elizabeth Holley-Guthrie, Lishan Su, Liang Cheng, Haitao Guo, Jenny P.-Y. Ting, Khader Ghneim, David M. Margolis, Leigh Anne Eller, Li Wang, Qi Wang, Elena Rampanelli, Rafick-Pierre Sekaly
Publikováno v:
Nature immunology
Nature immunology, 22(4), 423-433. Nature Publishing Group
Nature immunology, 22(4), 423-433. Nature Publishing Group
Individuals infected with human immunodeficiency virus type-1 (HIV-1) show metabolic alterations of CD4+ T cells through unclear mechanisms with undefined consequences. We analyzed the transcriptome of CD4+ T cells from patients with HIV-1 and reveal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827c5bbae1632cfe1cb28686f79582d6
https://doi.org/10.1038/s41590-021-00898-1
https://doi.org/10.1038/s41590-021-00898-1
Autor:
Haitao, Guo, Qi, Wang, Khader, Ghneim, Li, Wang, Elena, Rampanelli, Elizabeth, Holley-Guthrie, Liang, Cheng, Carolina, Garrido, David M, Margolis, Leigh A, Eller, Merlin L, Robb, Rafick-Pierre, Sekaly, Xian, Chen, Lishan, Su, Jenny P-Y, Ting
Publikováno v:
Nature immunology. 22(4)
Individuals infected with human immunodeficiency virus type-1 (HIV-1) show metabolic alterations of CD4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daa91b5c3e6ab4d10889e3fe8acfa1f5
https://pubmed.ncbi.nlm.nih.gov/33767428
https://pubmed.ncbi.nlm.nih.gov/33767428
Autor:
Kelly E Roney, Brian P O'Connor, Haitao Wen, Eda K Holl, Elizabeth H Guthrie, Beckley K Davis, Stephen W Jones, Sushmita Jha, Lisa Sharek, Rafael Garcia-Mata, James E Bear, Jenny P-Y Ting
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24795 (2011)
Plexins are cell surface receptors widely studied in the nervous system, where they mediate migration and morphogenesis though the Rho family of small GTPases. More recently, plexins have been implicated in immune processes including cell-cell intera
Externí odkaz:
https://doaj.org/article/3102917f9ddd4ec0bf26a718cc1bd611
Autor:
Rachid El Morabiti, Karen V. Swanson, Jenny P.-Y. Ting, Glen N. Barber, Cathryn J. Kurkjian, Elizabeth Holley-Guthrie, Avani A. Pendse, Robert D. Junkins, Chris A. Benedict, Alex Petrucelli
Publikováno v:
The Journal of Experimental Medicine
In this issue of JEM, Swanson et al. report an unanticipated role for cGAMP in priming and activation of inflammasomes in addition to its well-characterized function as an endogenous second messenger inducing type I interferons in the cytosolic DNA-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5f81f8bbe33d8c531c9ec07c21ad9f3
https://doi.org/10.1084/jem.20171749
https://doi.org/10.1084/jem.20171749
Autor:
Denis Gris, Chris B. Moore, Elizabeth Holley-Guthrie, Irving C. Allen, Max Tze Han Huang, Daniel T. Bergstralh, Jenny P.-Y. Ting, Debra J. Taxman, Yu Lei
Publikováno v:
Journal of Biological Chemistry. 286:19605-19616
ASC/PYCARD is a common adaptor for a diverse set of inflammasomes that activate caspase-1, most prominently the NLR-based inflammasome. Mounting evidence indicates that ASC and these NLRs also elicit non-overlapping functions, but the molecular basis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e47f28b73c6862adc9e84c63eb8b4888
https://doi.org/10.1074/jbc.m111.221077
https://doi.org/10.1074/jbc.m111.221077
Autor:
Amy Mauser, Shannon C. Kenney, Dennis A. Simpson, William K. Kaufmann, Elizabeth Holley-Guthrie
Publikováno v:
Journal of Virology. 76:10030-10037
The Epstein-Barr virus immediate-early protein BZLF1 is a transcriptional activator that mediates the switch from latent to lytic infection. Here we demonstrate that BZLF1 induces both a G 2 block and a mitotic block in HeLa cells and inhibits chromo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86b8dadb49fdce7c3ce73e0927e8fc7
https://doi.org/10.1128/jvi.76.19.10030-10037.2002
https://doi.org/10.1128/jvi.76.19.10030-10037.2002
Publikováno v:
Journal of Analytical and Applied Pyrolysis. 62:365-373
The potential for using lasers as a highly directional thermal source in analytical pyrolysis studies is further investigated by the laser micropyrolysis GC–MS analysis of lignin moieties. Two woods representative of the main types of lignin (i.e.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9041a0ff79b66c67a12b1ced9531bfaa
https://doi.org/10.1016/s0165-2370(01)00135-8
https://doi.org/10.1016/s0165-2370(01)00135-8
Publikováno v:
Journal of Virology. 75:6228-6234
The Epstein-Barr virus (EBV) immediate-early protein BRLF1 is a transcriptional activator that mediates the switch from latent to lytic viral replication. Many transcriptional activators function, in part, due to an interaction with histone acetylase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab17cd02f5a68fddcbb9f69f2e04544
https://doi.org/10.1128/jvi.75.13.6228-6234.2001
https://doi.org/10.1128/jvi.75.13.6228-6234.2001
Publikováno v:
Organic Geochemistry. 31:635-643
Laser micropyrolysis GC–MS was used for in situ analysis of the coal and lignin components of a synthetic mixture. Designed to mimic environmental matrices such as soils and sediments, the mix comprised several possible soil precursors and was also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fb3c9e2a3691d7e7c784dffd0482cb2
https://doi.org/10.1016/s0146-6380(00)00048-6
https://doi.org/10.1016/s0146-6380(00)00048-6
Publikováno v:
Environmental Science & Technology. 34:2925-2930
Sorption of pyrene on various types of natural organic matter (NOM) varying in chemical composition (e.g. high aliphaticity or aromaticity) was examined in batch sorption studies. The NOM samples (cuticle, humin, humic acid, degraded lignin, peat and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ccb4c56d9b62d06b42a0755b1dd1aa3e
https://doi.org/10.1021/es9912877
https://doi.org/10.1021/es9912877