Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Elizabeth A. Giuliani"'
Autor:
Nancy E. Kohl, Charles A. Omer, Michael W. Conner, Neville J. Anthony, Joseph P. Davide, S. Jane Desolms, Elizabeth A. Giuliani, Robert P. Gomez, Samuel L. Graham, Kelly Hamilton, Laurence K. Handt, George D. Hartman, Kenneth S. Koblan, Astrid M. Kral, Patricia J. Miller, Scott D. Mosser, Timothy J. O'Neill, Elaine Rands, Michael D. Schaber, Jackson B. Gibbs, Allen Oliff
Publikováno v:
Nature Medicine. 1:792-797
For Ras oncoproteins to transform mammalian cells, they must be post-translationally modified with a farnesyl group in a reaction catalysed by the enzyme farnesyl-protein transferase (FPTase). Inhibitors of FPTase have therefore been proposed as anti
Autor:
M. Katharine Holloway, Jenny M. Wai, Thomas A. Halgren, Paula M. D. Fitzgerald, Joseph P. Vacca, Bruce D. Dorsey, Rhonda B. Levin, Wayne J. Thompson, L. Jenny Chen, S. Jane deSolms, Neil Gaffin, Arun K. Ghosh, Elizabeth A. Giuliani, Samuel L. Graham, James P. Guare, Randall W. Hungate, Terry A. Lyle, William M. Sanders, Thomas J. Tucker, Mark Wiggins, Catherine M. Wiscount, Otto W. Woltersdorf, Steven D. Young, Paul L. Darke, Joan A. Zugay
Publikováno v:
Journal of Medicinal Chemistry. 39:2280-2280