Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Elizabeth A. Fletcher"'
Autor:
Marcus Sammer, Kijin Seong, Norma Olvera, Susie L. Gronseth, Elizabeth Anderson-Fletcher, Junfeng Jiao, Alison Reese, Ioannis A. Kakadiaris
Publikováno v:
International Journal of Computational Intelligence Systems, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract This paper presents the development and functionalities of the AI-FEED web-based platform (ai-feed.ai), designed to address food and nutrition insecurity challenges within the food charity ecosystem. AI-FEED leverages advancements in artific
Externí odkaz:
https://doaj.org/article/9669d59ac7b64da8ad671e39a315d276
Autor:
Zachary Shea, Matheus Ogando do Granja, Elizabeth B. Fletcher, Yaojie Zheng, Patrick Bewick, Zhibo Wang, William M. Singer, Bo Zhang
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4203-4233 (2024)
The global demand for sustainable and nutritious food sources has catalyzed interest in legumes, known for their rich repertoire of health-promoting compounds. This review delves into the diverse array of bioactive peptides, protein subunits, isoflav
Externí odkaz:
https://doaj.org/article/b1e71d31359449f5abe0a55163e89a26
Autor:
Rajashree Rana, Andrew M. Shearer, Elizabeth K. Fletcher, Nga Nguyen, Srijoy Guha, Daniel H. Cox, Manal Abdelmalek, Ying Wang, James D. Baleja, Lidija Covic, Athan Kuliopulos
Publikováno v:
Molecular Metabolism, Vol 29, Iss , Pp 99-113 (2019)
Objective: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in
Externí odkaz:
https://doaj.org/article/c69cc31ef2c14202b3177a40d35cc47e
Autor:
Andrew M. Shearer, Yanling Wang, Elizabeth K. Fletcher, Rajashree Rana, Emily S. Michael, Nga Nguyen, Manal F. Abdelmalek, Lidija Covic, Athan Kuliopulos
Publikováno v:
Hepatology (Baltimore, Md.). 76(6)
Insulin resistance and poor glycemic control are key drivers of the development of NAFLD and have recently been shown to be associated with fibrosis progression in NASH. However, the underlying mechanisms involving dysfunctional glucose metabolism an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b288205deeff312daf3bc0e4098ed245
https://pubmed.ncbi.nlm.nih.gov/35603482
https://pubmed.ncbi.nlm.nih.gov/35603482
Autor:
Kevin P. Bliden, Paul A. Gurbel, Lidija Covic, Athan Kuliopulos, Elizabeth K. Fletcher, Susan E. Turner, Jeffrey J. Rade, Daniel H. Cox, Carey Kimmelstiel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective: Arterial thrombosis leading to ischemic injury worsens the prognosis of many patients with cardiovascular disease. PZ-128 is a first-in-class pepducin that reversibly inhibits PAR
Objective: Arterial thrombosis leading to ischemic injury worsens the prognosis of many patients with cardiovascular disease. PZ-128 is a first-in-class pepducin that reversibly inhibits PAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5052005b268ffa6d4cd4b7e56b0e6f33
https://doi.org/10.1161/atvbaha.120.315168
https://doi.org/10.1161/atvbaha.120.315168
Autor:
Elizabeth K. Fletcher, Athan Kuliopulos, Nga Nguyen, Srijoy Guha, Andrew Shearer, Daniel H. Cox, James D. Baleja, Ying Wang, Manal F. Abdelmalek, Lidija Covic, Rajashree Rana
Publikováno v:
Molecular Metabolism, Vol 29, Iss, Pp 99-113 (2019)
Molecular Metabolism
Molecular Metabolism
Objective Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657ad1d365038a85001d7ddfc24d254b
http://www.sciencedirect.com/science/article/pii/S2212877819306982
http://www.sciencedirect.com/science/article/pii/S2212877819306982
Autor:
Paul A. Gurbel, Laura K. Flynn, Athan Kuliopulos, Elizabeth K. Fletcher, Susan E. Turner, Yanling Wang, Carey Kimmelstiel, Kevin P. Bliden, Jeffrey J. Rade, Lidija Covic
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: Destruction of arterial collagen allows monocyte and macrophage infiltration leading to atherosclerotic plaque formation, but it is not clear what role the MMP1 (matrix metalloprotease 1) collagenase plays in this process in vivo. To defin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab3a0114da1724fa7269f4b95af7c470
https://doi.org/10.1161/atvbaha.120.315837
https://doi.org/10.1161/atvbaha.120.315837
Autor:
Lidija Covic, Elizabeth K. Fletcher, Nga Nguyen, Christopher Garzia, Layla Van Doren, Athan Kuliopulos, Ryan Stevenson, David Jaramillo
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective: 12-LOX (12-lipoxygenase) produces a number of bioactive lipids including 12(S)-HETE that are involved in inflammation and platelet reactivity. The GPR31 (G-protein–coupled receptor 31) is the proposed receptor of 12(S)-HETE; however, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cebf75341ca44e408ea3b8447bc2e280
https://doi.org/10.1161/atvbaha.120.315154
https://doi.org/10.1161/atvbaha.120.315154
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47478 (2012)
In dolphins, natural selection has developed unihemispheric sleep where alternating hemispheres of their brain stay awake. This allows dolphins to maintain consciousness in response to respiratory demands of the ocean. Unihemispheric sleep may also a
Externí odkaz:
https://doaj.org/article/79b4093745994df2a8ce8be3ee4c98b2
Autor:
Georgios Koukos, Andrew Shearer, Athan Kuliopulos, Susan E. Turner, Jeffrey J. Rade, Elizabeth K. Fletcher, Tianfang Huang, Rajashree Rana, Carey Kimmelstiel, Kevin P. Bliden, Lidija Covic, Paul A. Gurbel
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:1368-1380
Objective— Protease-activated receptor-1 (PAR1) is classically activated by thrombin and is critical in controlling the balance of hemostasis and thrombosis. More recently, it has been shown that noncanonical activation of PAR1 by matrix metallopro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2bdf3eb2bb972138bb202d37bc3891e9
https://doi.org/10.1161/atvbaha.118.310967
https://doi.org/10.1161/atvbaha.118.310967