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pro vyhledávání: '"Elizabeth A. Booth-Gauthier"'
Publikováno v:
Biophysical Journal. 103(12):2423-2431
Extracellular mechanical forces result in changes in gene expression, but it is unclear how cells are able to permanently adapt to new mechanical environments because chemical signaling pathways are short-lived. We visualize force-induced changes in
Publikováno v:
Cellular and Molecular Bioengineering. 4:106-115
The structure and function of spectrins and spectrin networks have been well-studied in erythrocytes, but the role of spectrins in the cytoskeleton of non-erythroid cells remains unclear. Recent studies with RNAi of αII-spectrin in cells showed redu
Publikováno v:
ASME 2010 Summer Bioengineering Conference, Parts A and B.
Mechanical force is found to be increasingly important during development and for proper homeostatic maintenance of cells and tissues. The nucleus occupies a large volume fraction of the cell and is interconnected with the cytoskeleton. Here, to dete
Autor:
Marion Ghibaudo, Andrew D. Rape, Benoit Ladoux, Kris Noel Dahl, Vicard Du, Elizabeth A. Booth-Gauthier
Publikováno v:
Integrative Biology. 5:569
Cell migration through tight interstitial spaces in three dimensional (3D) environments impacts development, wound healing and cancer metastasis and is altered by the aging process. The stiffness of the extracellular matrix (ECM) increases with aging