Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Elizabeth A. Blaber"'
Autor:
Ying Ye, Wenyan Xie, Zhaoru Ma, Xuepeng Wang, Yi Wen, Xuemei Li, Hongqian Qi, Hao Wu, Jinnan An, Yan Jiang, Xinyi Lu, Guokai Chen, Shijun Hu, Elizabeth A. Blaber, Xi Chen, Lei Chang, Wensheng Zhang
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Embryonic stem cells (ESCs) exhibit unique attributes of boundless self-renewal and pluripotency, making them invaluable for fundamental investigations and clinical endeavors. Previous examinations of microgravity effects on ESC self-renewal
Externí odkaz:
https://doaj.org/article/4eb06d043c0344e8b17d30e399cd6305
Autor:
Meghana Pendyala, Paige S. Woods, Douglas K. Brubaker, Elizabeth A. Blaber, Tannin A. Schmidt, Deva D. Chan
Publikováno v:
PLoS ONE, Vol 17, Iss 12 (2022)
Synovial fluid is composed of hyaluronan and proteoglycan-4 (PRG4 or lubricin), which work synergistically to maintain joint lubrication. In diseases like osteoarthritis, hyaluronan and PRG4 concentrations can be altered, resulting in lowered synovia
Externí odkaz:
https://doaj.org/article/c95978e980974b3482e560433edc27d3
Autor:
Cassandra M. Juran, Justina Zvirblyte, Margareth Cheng-Campbell, Elizabeth A. Blaber, Eduardo A.C. Almeida
Publikováno v:
Stem Cell Research, Vol 56, Iss , Pp 102513- (2021)
CDKN1A/P21 is a potent inhibitor of cell cycle progression and its overexpression is thought to be associated with inhibition of normal bone regenerative osteogenesis during spaceflight. To test whether CDKN1A/P21 regulates osteogenesis in response t
Externí odkaz:
https://doaj.org/article/882ae64eb25f4d5490c1bb0b475262ba
Autor:
Eliah G. Overbey, Amanda M. Saravia-Butler, Zhe Zhang, Komal S. Rathi, Homer Fogle, Willian A. da Silveira, Richard J. Barker, Joseph J. Bass, Afshin Beheshti, Daniel C. Berrios, Elizabeth A. Blaber, Egle Cekanaviciute, Helio A. Costa, Laurence B. Davin, Kathleen M. Fisch, Samrawit G. Gebre, Matthew Geniza, Rachel Gilbert, Simon Gilroy, Gary Hardiman, Raúl Herranz, Yared H. Kidane, Colin P.S. Kruse, Michael D. Lee, Ted Liefeld, Norman G. Lewis, J. Tyson McDonald, Robert Meller, Tejaswini Mishra, Imara Y. Perera, Shayoni Ray, Sigrid S. Reinsch, Sara Brin Rosenthal, Michael Strong, Nathaniel J. Szewczyk, Candice G.T. Tahimic, Deanne M. Taylor, Joshua P. Vandenbrink, Alicia Villacampa, Silvio Weging, Chris Wolverton, Sarah E. Wyatt, Luis Zea, Sylvain V. Costes, Jonathan M. Galazka
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102361- (2021)
Summary: With the development of transcriptomic technologies, we are able to quantify precise changes in gene expression profiles from astronauts and other organisms exposed to spaceflight. Members of NASA GeneLab and GeneLab-associated analysis work
Externí odkaz:
https://doaj.org/article/db05f4c13f9d4050b634492f121e3d68
Autor:
Yen-Ruh Wuu, Burong Hu, Hazeem Okunola, Amber M. Paul, Elizabeth A. Blaber, Margareth Cheng-Campbell, Afshin Beheshti, Peter Grabham
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101771- (2020)
Summary: Space radiation inhibits angiogenesis by two mechanisms depending on the linear energy transfer (LET). Using human 3D micro-vessel models, blockage of the early motile stage of angiogenesis was determined to occur after exposure to low LET i
Externí odkaz:
https://doaj.org/article/57c58450f3264087a7aefd88a103603f
Autor:
Amber M. Paul, Margareth Cheng-Campbell, Elizabeth A. Blaber, Sulekha Anand, Sharmila Bhattacharya, Sara R. Zwart, Brian E. Crucian, Scott M. Smith, Robert Meller, Peter Grabham, Afshin Beheshti
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101747- (2020)
Summary: Spaceflight missions can cause immune system dysfunction in astronauts with little understanding of immune outcomes in deep space. This study assessed immune responses in mice following ground-based, simulated deep spaceflight conditions, co
Externí odkaz:
https://doaj.org/article/dd95f6efd99344169798c95585dd9c53
Publikováno v:
International Journal of Molecular Sciences, Vol 18, Iss 10, p 2062 (2017)
Increased oxidative stress is an unavoidable consequence of exposure to the space environment. Our previous studies showed that mice exposed to space for 13.5 days had decreased glutathione levels, suggesting impairments in oxidative defense. Here we
Externí odkaz:
https://doaj.org/article/ea7a4e7e8c5d4725a243b568bf8ec692
Publikováno v:
Bone. 172:116779
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f803e9d11cddf89ca8eff754a0706fe4
https://doi.org/10.1016/j.bone.2023.116779
https://doi.org/10.1016/j.bone.2023.116779
Autor:
Marie Mortreux, Angela J Kubik, Candice Tahimic, Larry D. Sanford, Xiao Wen Mao, Michael D. Delp, Jeffrey Chancellor, Jeffrey S. Willey, Richard A. Britten, Elizabeth A. Blaber
Publikováno v:
J Environ Sci Health C Toxicol Carcinog
Both microgravity and radiation exposure in the spaceflight environment have been identified as hazards to astronaut health and performance. Substantial study has been focused on understanding the biology and risks associated with prolonged exposure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e956dc3f3c01857660776459903635c
https://doi.org/10.1080/26896583.2021.1885283
https://doi.org/10.1080/26896583.2021.1885283
Autor:
Elizabeth A. Blaber, George Collins, Eduardo A. C. Almeida, Treena Livingston Arinzeh, Jessica Cardenas Turner
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 14:173-185
Bone fractures often result in complications that require surgical intervention to promote fracture healing. Tissue engineering seeks to alleviate the need for autologous bone grafting by utilizing scaffolds that can promote bone fracture healing. Pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfd3ca0bf13bc140ee108903e498f4a
https://doi.org/10.1002/term.2984
https://doi.org/10.1002/term.2984