Výsledky vyhledávání - "Elizabeth A Zegarac"

Safety, tolerability, and pharmacokinetics of pregabalin in children with refractory partial seizures: A phase 1, randomized controlled study

Autor: Verne Pitman, Christine Alvey, Jing Liu, Elizabeth A Zegarac, John M. Pellock, Donald W. Mann, Howard N. Bockbrader, Marci L. Chew

Publikováno v: Epilepsia. 55:1934-1943

To evaluate the safety, tolerability, and pharmacokinetics (PK) of pregabalin as adjunctive therapy in children with refractory partial seizures.This was a phase 1, randomized, placebo-controlled, parallel-group, escalating-dose, multiple-dose study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc3ecc91d53ca7e6270b61ecb5bcf8f3
https://doi.org/10.1111/epi.12830

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The Effect of Food on the Bioavailability of Norethindrone and Ethinyl Estradiol from Norethindrone Acetate/Ethinyl Estradiol Tablets Intended for Continuous Hormone Replacement Therapy

Autor: Rebecca A. Boyd, Elizabeth A. Zegarac, Michael A. Eldon

Publikováno v: The Journal of Clinical Pharmacology. 43:52-58

As part of the development of a combination product containing norethindrone acetate and low-dose ethinyl estradiol for continuous hormone replacement therapy in postmenopausal women, a study was conducted to determine the effect of a high-fat meal o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714103c584be5bd5fcde7d0b402f09aa
https://doi.org/10.1177/0091270002239706

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Atorvastatin Coadministration May Increase Digoxin Concentrations by Inhibition of Intestinal P-Glycoprotein-Mediated Secretion

Autor: Ralph H. Stern, Elizabeth A. Zegarac, Rebecca A. Boyd, Barhra H. Stewart, Eric L. Reyner, Xiaochun Wu, Lloyd R. Whitfield, Edward J. Randinitis

Publikováno v: Journal of Clinical Pharmacology. 40:91-98

The effect of atovarstatin on digoxin pharmacokinetics was assessed in 24 healthy volunteers in two studies. Subjects received 0.25 mg digoxin daily for 20 days, administered alone for the first 10 days and concomitantly with 10 mg or 80 mg atorvasta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edad63904e5cbec047db0a02b32596a4
https://doi.org/10.1177/00912700022008612

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CHARACTERIZATION OF A 7 DAY 17β-ESTRADIOL TRANSDERMAL DELIVERY SYSTEM: PHARMACOKINETICS IN HEALTHY POSTMENOPAUSAL WOMEN

Autor: Rebecca A. Boyd, Elizabeth A. Zegarac, S. Thomas Forgue, Allen J. Sedman, Michael A. Eldon

Publikováno v: Biopharmaceutics & Drug Disposition. 17:459-470

To assess the delivery characteristics of a new 7 day 17 beta-estradiol transdermal delivery system (TDS), estradiol and estrone pharmacokinetics were evaluated following a single 7 d application of one TDS or two TDSs in 24 healthy, postmenopausal w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::29d18678bcd66370f49e9ee8422cc650
https://doi.org/10.1002/(sici)1099-081x(199608)17:6<459::aid-bdd973>3.0.co

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Minimal androgenic activity of a new oral contraceptive containing norethindrone acetate and graduated doses of ethinyl estradiol

Autor: Mary R Flack, Edward L. Posvar, Rebecca A. Boyd, Elizabeth A Zegarac

Publikováno v: Contraception. 63(2)

The pharmacokinetics and androgenic activity of Estrostep, a new oral contraceptive providing low-dose estrogen in a graduated sequence with a constant dose of progestin, were characterized in an open-label, nonrandomized study in 17 normally cycling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30befd850db4e168a71f907b3f737954
https://pubmed.ncbi.nlm.nih.gov/11292470

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