Výsledky vyhledávání - "Elizabeth A Mueller"

Akademický článek

Structure-guided microbial targeting of antistaphylococcal prodrugs

Autor: Justin J Miller, Ishaan T Shah, Jayda Hatten, Yasaman Barekatain, Elizabeth A Mueller, Ahmed M Moustafa, Rachel L Edwards, Cynthia S Dowd, Geoffrey C Hoops, R Jeremy Johnson, Paul J Planet, Florian L Muller, Joseph M Jez, Audrey R Odom John

Publikováno v: eLife, Vol 10 (2021)

Carboxy ester prodrugs are widely employed to increase oral absorption and potency of phosphonate antibiotics. Prodrugging can mask problematic chemical features that prevent cellular uptake and may enable tissue-specific compound delivery. However,

Externí odkaz: https://doaj.org/article/17f733fe025245b6a2dbe45ff732edb9

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Akademický článek

pH-dependent activation of cytokinesis modulates Escherichia coli cell size.

Autor: Elizabeth A Mueller, Corey S Westfall, Petra Anne Levin

Publikováno v: PLoS Genetics, Vol 16, Iss 3, p e1008685 (2020)

Cell size is a complex trait, derived from both genetic and environmental factors. Environmental determinants of bacterial cell size identified to date primarily target assembly of cytosolic components of the cell division machinery. Whether certain

Externí odkaz: https://doaj.org/article/d808eeb162a24f2b8e8c44bc3cb55624

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Akademický článek

Plasticity of Escherichia coli cell wall metabolism promotes fitness and antibiotic resistance across environmental conditions

Autor: Elizabeth A Mueller, Alexander JF Egan, Eefjan Breukink, Waldemar Vollmer, Petra Anne Levin

Publikováno v: eLife, Vol 8 (2019)

Although the peptidoglycan cell wall is an essential structural and morphological feature of most bacterial cells, the extracytoplasmic enzymes involved in its synthesis are frequently dispensable under standard culture conditions. By modulating a si

Externí odkaz: https://doaj.org/article/8bf3e3bbbd434048af773b1d95d9721c

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Akademický článek

Design of a Tool Capable of Assessing Environmental Sociocultural Physical Factors Influencing Women’s Decisions on When and Where to Toilet Within Real-World Settings: Protocol for the Build and Usability Testing of a Mobile App for Use by Community-Dwelling Women

Autor: Janis M Miller, Jean F Wyman, Lawrence An, Haitao Chu, Cynthia S Fok, Missy Lavender, Cora Elizabeth Lewis, Alayne D Markland, Leslie M Rickey, Ying Sheng, Siobhan Sutcliffe, Lisa Kane Low, Elizabeth R Mueller

Publikováno v: JMIR Research Protocols, Vol 13, p e54046 (2024)

BackgroundAlthough surveys and apps are available for women to report urination and bladder symptoms, they do not include their decisions regarding toileting. Real-world factors can interfere with toileting decisions, which may then influence bladder

Externí odkaz: https://doaj.org/article/01a235bdf39f49fa823c0bdcf48b612d

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Akademický článek

Non-aqueous glycerol monolaurate gel exhibits antibacterial and anti-biofilm activity against Gram-positive and Gram-negative pathogens.

Autor: Elizabeth A Mueller, Patrick M Schlievert

Publikováno v: PLoS ONE, Vol 10, Iss 3, p e0120280 (2015)

Skin and surgical infections due to Staphylococcus aureus, Pseudomonas aeruginosa, and Acinetobacter baumannii are causes of patient morbidity and increased healthcare costs. These organisms grow planktonically and as biofilms, and many strains exhib

Externí odkaz: https://doaj.org/article/95280ab65e39485da1c623e984b491aa

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