Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Elizabeth A Jonas"'
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 12-15 (2021)
Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, development, and maturation of neurons, and it also prevents neuronal death during neurotoxic stimulation. This article reviews the mecha
Externí odkaz:
https://doaj.org/article/cbbbcea7418843529fc91d500fcc9479
Autor:
Han-A Park, Elizabeth A Jonas
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 11, Pp 1791-1794 (2017)
The B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial anti-apoptotic protein that plays a role in neuroprotection. However, during excitotoxic stimulation, Bcl-xL undergoes caspase-dependent cleavage and produces a fragmented form, ΔN-Bcl-xL.
Externí odkaz:
https://doaj.org/article/ff1c8c3f91ad4b5bb626fd0c654ae473
Autor:
Pawel Licznerski, Vanja Duric, Mounira Banasr, Kambiz N Alavian, Kristie T Ota, Hyo Jung Kang, Elizabeth A Jonas, Robert Ursano, John H Krystal, Ronald S Duman, Traumatic Stress Brain Study Group
Publikováno v:
PLoS Biology, Vol 13, Iss 10, p e1002282 (2015)
Exposure to extreme stress can trigger the development of major depressive disorder (MDD) as well as post-traumatic stress disorder (PTSD). The molecular mechanisms underlying the structural and functional alterations within corticolimbic brain regio
Externí odkaz:
https://doaj.org/article/80f1f1c285684de08991174b81c6301c
Autor:
Han-A Park, Spenser R. Brown, Joseph Jansen, Tracie Dunn, Madison Scott, Nelli Mnatsakanyan, Elizabeth A. Jonas, Yonghyun Kim
Publikováno v:
Biochemical and Biophysical Research Communications. 632:173-180
Autor:
Han-A Park, Kristi M. Crowe-White, Lukasz Ciesla, Madison Scott, Sydni Bannerman, Abigail U. Davis, Bishnu Adhikari, Garrett Burnett, Katheryn Broman, Khondoker Adeba Ferdous, Kimberly H. Lackey, Pawel Licznerski, Elizabeth A. Jonas
Publikováno v:
Nutr Res
Alpha-tocotrienol (α-TCT) is a member of the vitamin E family. It has been reported to protect the brain against various pathologies including cerebral ischemia and neurodegeneration. However, it is still unclear if α-TCT exhibits beneficial effect
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Autor:
Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc C. Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Joachim Weber, Richard J. Levy, Evgeny V. Pavlov, Elizabeth A. Jonas
Publikováno v:
Cell Death & Differentiation. 29:1874-1887
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Autor:
Linlin Sun, Catarina M. Quinzii, Matthew Tracey, Elizabeth A. Jonas, Jose F. Perez-Zoghbi, Pawel Licznerski, Giulio Kleiner, Aili Wang, Richard J. Levy, Mu Yang, Lifei Wang, Guang Yang, Keren K. Griffiths
Publikováno v:
FASEB J
Fragile X syndrome (FXS) is the leading known inherited intellectual disability and the most common genetic cause of autism. The full mutation results in transcriptional silencing of the Fmr1 gene and loss of fragile X mental retardation protein (FMR
Publikováno v:
Biophysical Journal. 122:93a
Autor:
Nelli, Mnatsakanyan, Han-A, Park, Jing, Wu, Xiang, He, Marc C, Llaguno, Maria, Latta, Paige, Miranda, Besnik, Murtishi, Morven, Graham, Joachim, Weber, Richard J, Levy, Evgeny V, Pavlov, Elizabeth A, Jonas
Publikováno v:
Cell death and differentiation. 29(9)
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1863:148774