Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Elizabeth A Hubin"'
Autor:
Elizabeth A Hubin, Allison Fay, Catherine Xu, James M Bean, Ruth M Saecker, Michael S Glickman, Seth A Darst, Elizabeth A Campbell
Publikováno v:
eLife, Vol 6 (2017)
RbpA and CarD are essential transcription regulators in mycobacteria. Mechanistic analyses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate formation of an intermediate (RP2) leading to RPo; formation of R
Externí odkaz:
https://doaj.org/article/fb7a564ed06b473b809505503645860d
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Understanding of the mycobacterial transcription system is useful to the development of therapeutics against tuberculosis infection. Here the authors present the crystal structure of a completeM. smegmatisRNA polymerase open promoter complex that rev
Externí odkaz:
https://doaj.org/article/133287ec42704d49bf169ec537d59a2a
Autor:
Rolf Müller, Robert Landick, Mirjana Lilic, Jennifer Herrmann, Rachel A. Mooney, Hande Boyaci, Elizabeth A. Campbell, Nathaniel Braffman, James Chen, Seth A. Darst, Elizabeth A. Hubin
Publikováno v:
Proceedings of the National Academy of Sciences. 117:30423-30432
Rifampicin (Rif) is a first-line therapeutic used to treat the infectious disease tuberculosis (TB), which is caused by the pathogen Mycobacterium tuberculosis (Mtb). The emergence of Rif-resistant (RifR) Mtb presents a need for new antibiotics. Rif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::038f8c5dca67119d2bd0813433e513d7
https://doi.org/10.1073/pnas.2013706117
https://doi.org/10.1073/pnas.2013706117
Autor:
Mirjana, Lilic, James, Chen, Hande, Boyaci, Nathaniel, Braffman, Elizabeth A, Hubin, Jennifer, Herrmann, Rolf, Müller, Rachel, Mooney, Robert, Landick, Seth A, Darst, Elizabeth A, Campbell
Publikováno v:
Proc Natl Acad Sci U S A
Rifampicin (Rif) is a first-line therapeutic used to treat the infectious disease tuberculosis (TB), which is caused by the pathogen Mycobacterium tuberculosis (Mtb). The emergence of Rif-resistant (Rif(R)) Mtb presents a need for new antibiotics. Ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b585d074f1b99756059282c029ff82d1
https://pubmed.ncbi.nlm.nih.gov/33199626
https://pubmed.ncbi.nlm.nih.gov/33199626
Autor:
Ruth M. Saecker, Catherine K. Xu, Michael S. Glickman, Jonathan F. Bean, Allison Fay, Elizabeth A. Campbell, Seth A. Darst, Elizabeth A. Hubin
Publikováno v:
eLife, Vol 6 (2017)
eLife
eLife
RbpA and CarD are essential transcription regulators in mycobacteria. Mechanistic analyses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate formation of an intermediate (RP2) leading to RPo; formation of R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d722c57da1422342f92d0c4996b6b85
https://elifesciences.org/articles/22520
https://elifesciences.org/articles/22520
Autor:
Jonathan F. Bean, Seth A. Darst, Elizabeth A. Hubin, Allison Fay, Elizabeth A. Campbell, Ruth M. Saecker, Catherine K. Xu, Michael S. Glickman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d40ef24e759df3462e5626d580b1837a
https://doi.org/10.7554/elife.22520.047
https://doi.org/10.7554/elife.22520.047
Autor:
Paul Dominic B. Olinares, Joshua E. Flack, Elizabeth A. Hubin, Aline Tabib-Salazar, Laurence J. Humphrey, Seth A. Darst, Elizabeth A. Campbell, Mark S. B. Paget
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(23)
Gene expression is highly regulated at the step of transcription initiation, and transcription activators play a critical role in this process. RbpA, an actinobacterial transcription activator that is essential in Mycobacterium tuberculosis (Mtb), bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74a56a08a21c4f96d65f1af54c93488e
https://pubmed.ncbi.nlm.nih.gov/26040003
https://pubmed.ncbi.nlm.nih.gov/26040003