Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Elizabeth A Campbell"'
Autor:
Olumide Abiodun Elebute, Elizabeth A Campbell, Adesoji O Ademuyiwa, Chibuike George Ihediwa, Christopher O Bode
Publikováno v:
Journal of Clinical Sciences, Vol 20, Iss 1, Pp 8-14 (2023)
Background: There is a paucity of literature on the psychological burden on parental caregivers of children with surgical conditions. Knowledge of the peculiar psychological challenges faced by the parents or caregivers could help to advocate for the
Externí odkaz:
https://doaj.org/article/d8d72d57bb1c4e739f76cd6e7b667db9
Autor:
Elizabeth A Campbell, Mitchell G Maltenfort, Justine Shults, Christopher B Forrest, Aaron J Masino
Publikováno v:
PLOS Digital Health, Vol 1, Iss 8, p e0000073 (2022)
In this work, we present a study of electronic health record (EHR) data that aims to identify pediatric obesity clinical subtypes. Specifically, we examine whether certain temporal condition patterns associated with childhood obesity incidence tend t
Externí odkaz:
https://doaj.org/article/8e2748e62319466496b2071c911d58bd
Autor:
Jin Young Kang, Eliza Llewellyn, James Chen, Paul Dominic B Olinares, Joshua Brewer, Brian T Chait, Elizabeth A Campbell, Seth A Darst
Publikováno v:
eLife, Vol 10 (2021)
Transcription-coupled repair (TCR) is a sub-pathway of nucleotide excision repair (NER) that preferentially removes lesions from the template-strand (t-strand) that stall RNA polymerase (RNAP) elongation complexes (ECs). Mfd mediates TCR in bacteria
Externí odkaz:
https://doaj.org/article/8123ee31e7b74c728b593caaed97ace4
Autor:
James Chen, Saumya Gopalkrishnan, Courtney Chiu, Albert Y Chen, Elizabeth A Campbell, Richard L Gourse, Wilma Ross, Seth A Darst
Publikováno v:
eLife, Vol 8 (2019)
TraR and its homolog DksA are bacterial proteins that regulate transcription initiation by binding directly to RNA polymerase (RNAP) rather than to promoter DNA. Effects of TraR mimic the combined effects of DksA and its cofactor ppGpp, but the struc
Externí odkaz:
https://doaj.org/article/e1305efd59cf4fd8a2295eb97b7ac9aa
Autor:
Motunrayo A Oyelohunnu, Yewande O Oshodi, Elizabeth A Campbell, Mercy Eigbike, Kofoworola A Odeyemi
Publikováno v:
Journal of Clinical Sciences, Vol 13, Iss 3, Pp 105-111 (2016)
Background: Maternal mental health, in particular depression, has been found to negatively impact mother-child interaction, attachment, stimulation, growth, and many important aspects of development in the young child. These early deficits if sustain
Externí odkaz:
https://doaj.org/article/6fea461a440641ea92bb24da2c7c3c18
Autor:
Hande Boyaci, James Chen, Mirjana Lilic, Margaret Palka, Rachel Anne Mooney, Robert Landick, Seth A Darst, Elizabeth A Campbell
Publikováno v:
eLife, Vol 7 (2018)
Fidaxomicin (Fdx) is an antimicrobial RNA polymerase (RNAP) inhibitor highly effective against Mycobacterium tuberculosis RNAP in vitro, but clinical use of Fdx is limited to treating Clostridium difficile intestinal infections due to poor absorption
Externí odkaz:
https://doaj.org/article/ed35d087085b40cab9518a2253b5c555
Autor:
Jin Young Kang, Paul Dominic B Olinares, James Chen, Elizabeth A Campbell, Arkady Mustaev, Brian T Chait, Max E Gottesman, Seth A Darst
Publikováno v:
eLife, Vol 6 (2017)
Coliphage HK022 Nun blocks superinfection by coliphage λ by stalling RNA polymerase (RNAP) translocation specifically on λ DNA. To provide a structural framework to understand how Nun blocks RNAP translocation, we determined structures of Escherich
Externí odkaz:
https://doaj.org/article/5854e80359a44629abd62f3c1fc151e5
Autor:
Elizabeth A Hubin, Allison Fay, Catherine Xu, James M Bean, Ruth M Saecker, Michael S Glickman, Seth A Darst, Elizabeth A Campbell
Publikováno v:
eLife, Vol 6 (2017)
RbpA and CarD are essential transcription regulators in mycobacteria. Mechanistic analyses of promoter open complex (RPo) formation establish that RbpA and CarD cooperatively stimulate formation of an intermediate (RP2) leading to RPo; formation of R
Externí odkaz:
https://doaj.org/article/fb7a564ed06b473b809505503645860d
Publikováno v:
eLife, Vol 4 (2015)
A key point to regulate gene expression is at transcription initiation, and activators play a major role. CarD, an essential activator in Mycobacterium tuberculosis, is found in many bacteria, including Thermus species, but absent in Escherichia coli
Externí odkaz:
https://doaj.org/article/24074d1ff14e498d924354ef3c28dc71
Publikováno v:
Microbial Cell, Vol 9, Iss 7, Pp 136-138 (2022)
Clostridioides difficile (Cdiff) infection (CDI) continues to be the leading threat of nosocomial deaths worldwide and a major burden on health-care systems. Broad-spectrum antibiotics eradicate the normal gut microbiome, killing protective commensal
Externí odkaz:
https://doaj.org/article/f785248acab24872bb717747d2df4b75