Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Elizabeth A, Strychalski"'
Autor:
Jayan Rammohan, Steven P. Lund, Nina Alperovich, Vanya Paralanov, Elizabeth A. Strychalski, David Ross
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Rammohan et al. propose a generalizable framework for performing multiple methods in parallel using split samples, so that experimental variability is defined and compared between methods. Their framework provides a practical solution for benchmarkin
Externí odkaz:
https://doaj.org/article/18b4195254e744b8911081408a581ce2
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Genome-scale engineering requires the integration of a wide range of in silico and in vivo technologies, as well data management procedures and legal infrastructure. Here the authors provide a list of recommendations to address these challenges.
Externí odkaz:
https://doaj.org/article/6e2b00be562f422f97310610f3d902b6
Autor:
Jennifer L. Mantle, Jayan Rammohan, Eugenia F. Romantseva, Joel T. Welch, Leah R. Kauffman, Jim McCarthy, John Schiel, Jeffrey C. Baker, Elizabeth A. Strychalski, Kelley C. Rogers, Kelvin H. Lee
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Cyberbiosecurity is an emerging discipline that addresses the unique vulnerabilities and threats that occur at the intersection of cyberspace and biotechnology. Advances in technology and manufacturing are increasing the relevance of cyberbiosecurity
Externí odkaz:
https://doaj.org/article/9a9414ec906b4e9c95fe3bf0ff2c0e7f
Cotranscriptionally encoded RNA strand displacement (ctRSD) circuits are an emerging tool for programmable molecular computation with potential applications spanningin vitrodiagnostics to continuous computation inside living cells. In ctRSD circuits,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f00d273100789358801b5acb05deff
https://doi.org/10.1101/2023.02.01.526534
https://doi.org/10.1101/2023.02.01.526534
Autor:
David L. Ross, Nina Alperovich, Vanya Paralanov, Jayan Rammohan, Steven P. Lund, Elizabeth A. Strychalski
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
Single-cell and single-transcript measurement methods have elevated our ability to understand and engineer biological systems. However, defining and comparing performance between methods remains a challenge, in part due to the confounding effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71848337defd65cf5cc06608e3ba1b6d
https://doaj.org/article/18b4195254e744b8911081408a581ce2
https://doaj.org/article/18b4195254e744b8911081408a581ce2
Autor:
Eugenia F. Romantseva, Drew S. Tack, Elizabeth A. Strychalski, Peter D. Tonner, Abe Pressman, Jayan Rammohan
Publikováno v:
Curr Opin Syst Biol
Precise engineering of biological systems requires quantitative, high-throughput measurements, exemplified by progress in directed evolution. New approaches allow high-throughput measurements of phenotypes and their corresponding genotypes. When inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609a9b83bf33ccd16c89146a0849c2d8
https://doi.org/10.1016/j.coisb.2020.09.004
https://doi.org/10.1016/j.coisb.2020.09.004
Publikováno v:
Trends in cell biology. 32(11)
Genomically minimal cells, such as JCVI-syn3.0 and JCVI-syn3A, offer an empowering framework to study relationships between genotype and phenotype. With a polygenic basis, the fundamental physiological process of cell division depends on multiple gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb9180286d9750f44d7228946639288
https://pubmed.ncbi.nlm.nih.gov/35907702
https://pubmed.ncbi.nlm.nih.gov/35907702
Publikováno v:
Synth Biol (Oxf)
DNA templates for protein production remain an unexplored source of variability in the performance of cell-free expression (CFE) systems. To characterize this variability, we investigated the effects of two common DNA extraction methodologies, a post
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d9aed443cd1ab49ea60788e4e1b7f3f
https://pubmed.ncbi.nlm.nih.gov/36046152
https://pubmed.ncbi.nlm.nih.gov/36046152
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2433
Performance variability is a common challenge in cell-free protein production and hinders a wider adoption of these systems for both research and biomanufacturing. While the inherent stochasticity and complexity of biology likely contributes to varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::58938ae1d0f0e704f5d53164235461bd
https://pubmed.ncbi.nlm.nih.gov/34985735
https://pubmed.ncbi.nlm.nih.gov/34985735
Publikováno v:
Cell-Free Gene Expression ISBN: 9781071619971
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3617e152a3eed9fcf8c070757d364dc4
https://doi.org/10.1007/978-1-0716-1998-8_1
https://doi.org/10.1007/978-1-0716-1998-8_1