Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Elizabeth A, Jonas"'
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 12-15 (2021)
Bcl-xL is a pro-survival protein of the Bcl2 family found in the mitochondrial membrane. Bcl-xL supports growth, development, and maturation of neurons, and it also prevents neuronal death during neurotoxic stimulation. This article reviews the mecha
Externí odkaz:
https://doaj.org/article/cbbbcea7418843529fc91d500fcc9479
Autor:
Nelli Mnatsakanyan, Marc C. Llaguno, Youshan Yang, Yangyang Yan, Joachim Weber, Fred J. Sigworth, Elizabeth A. Jonas
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The ATP synthase has been suggested to contain the mitochondrial permeability transition pore (mPTP), which has a crucial role in cell death. Here the authors show that reconstituted ATP synthase monomers form voltage-gated and Ca2+ -activated channe
Externí odkaz:
https://doaj.org/article/1114e6356c4045608f3cc3526a4d63ca
Autor:
Han-A Park, Spenser R. Brown, Joseph Jansen, Tracie Dunn, Madison Scott, Nelli Mnatsakanyan, Elizabeth A. Jonas, Yonghyun Kim
Publikováno v:
Biochemical and Biophysical Research Communications. 632:173-180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::161178d810b98065cb29660c242bbee1
https://doi.org/10.1016/j.bbrc.2022.09.084
https://doi.org/10.1016/j.bbrc.2022.09.084
Autor:
Han-A Park, Elizabeth A Jonas
Publikováno v:
Neural Regeneration Research, Vol 12, Iss 11, Pp 1791-1794 (2017)
The B-cell lymphoma-extra large (Bcl-xL) is a mitochondrial anti-apoptotic protein that plays a role in neuroprotection. However, during excitotoxic stimulation, Bcl-xL undergoes caspase-dependent cleavage and produces a fragmented form, ΔN-Bcl-xL.
Externí odkaz:
https://doaj.org/article/ff1c8c3f91ad4b5bb626fd0c654ae473
Autor:
Han-A Park, Kristi M. Crowe-White, Lukasz Ciesla, Madison Scott, Sydni Bannerman, Abigail U. Davis, Bishnu Adhikari, Garrett Burnett, Katheryn Broman, Khondoker Adeba Ferdous, Kimberly H. Lackey, Pawel Licznerski, Elizabeth A. Jonas
Publikováno v:
Nutr Res
Alpha-tocotrienol (α-TCT) is a member of the vitamin E family. It has been reported to protect the brain against various pathologies including cerebral ischemia and neurodegeneration. However, it is still unclear if α-TCT exhibits beneficial effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cec30d201545065928e7752ffe95a14
https://doi.org/10.1016/j.nutres.2022.02.007
https://doi.org/10.1016/j.nutres.2022.02.007
Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex
Autor:
Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc C. Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Joachim Weber, Richard J. Levy, Evgeny V. Pavlov, Elizabeth A. Jonas
Publikováno v:
Cell Death & Differentiation. 29:1874-1887
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c4741c186f970772952c9a055389a99
https://doi.org/10.1038/s41418-022-00972-7
https://doi.org/10.1038/s41418-022-00972-7
Autor:
Linlin Sun, Catarina M. Quinzii, Matthew Tracey, Elizabeth A. Jonas, Jose F. Perez-Zoghbi, Pawel Licznerski, Giulio Kleiner, Aili Wang, Richard J. Levy, Mu Yang, Lifei Wang, Guang Yang, Keren K. Griffiths
Publikováno v:
FASEB J
Fragile X syndrome (FXS) is the leading known inherited intellectual disability and the most common genetic cause of autism. The full mutation results in transcriptional silencing of the Fmr1 gene and loss of fragile X mental retardation protein (FMR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95d16f52a57f3650872c94b59126e16c
https://doi.org/10.1096/fj.202000283rr
https://doi.org/10.1096/fj.202000283rr
Publikováno v:
Biophysical Journal. 122:93a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c914a4f403a8b50614d237a5d23b2a8c
https://doi.org/10.1016/j.bpj.2022.11.701
https://doi.org/10.1016/j.bpj.2022.11.701
Publikováno v:
Molecules, Vol 23, Iss 11, p 3019 (2018)
B-cell lymphoma-extra large (Bcl-xL) is an anti-apoptotic Bcl-2 protein found in the mitochondrial membrane. Bcl-xL is reported to support normal brain development and protects neurons against toxic stimulation during pathological process via its rol
Externí odkaz:
https://doaj.org/article/2ffb960bec5f43be9c9f1d2964797697
Autor:
Nelli, Mnatsakanyan, Han-A, Park, Jing, Wu, Xiang, He, Marc C, Llaguno, Maria, Latta, Paige, Miranda, Besnik, Murtishi, Morven, Graham, Joachim, Weber, Richard J, Levy, Evgeny V, Pavlov, Elizabeth A, Jonas
Publikováno v:
Cell death and differentiation. 29(9)
Mitochondrial ATP synthase is vital not only for cellular energy production but also for energy dissipation and cell death. ATP synthase c-ring was suggested to house the leak channel of mitochondrial permeability transition (mPT), which activates du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f743f27617309921dc9b5761972d30ce
https://pubmed.ncbi.nlm.nih.gov/35322203
https://pubmed.ncbi.nlm.nih.gov/35322203