Zobrazeno 1 - 10
of 309
pro vyhledávání: '"Elizabeth A, Grimm"'
Autor:
Miles C. Andrews, Junna Oba, Chang-Jiun Wu, Haifeng Zhu, Tatiana Karpinets, Caitlin A. Creasy, Marie-Andrée Forget, Xiaoxing Yu, Xingzhi Song, Xizeng Mao, A. Gordon Robertson, Gabriele Romano, Peng Li, Elizabeth M. Burton, Yiling Lu, Robert Szczepaniak Sloane, Khalida M. Wani, Kunal Rai, Alexander J. Lazar, Lauren E. Haydu, Matias A. Bustos, Jianjun Shen, Yueping Chen, Margaret B. Morgan, Jennifer A. Wargo, Lawrence N. Kwong, Cara L. Haymaker, Elizabeth A. Grimm, Patrick Hwu, Dave S. B. Hoon, Jianhua Zhang, Jeffrey E. Gershenwald, Michael A. Davies, P. Andrew Futreal, Chantale Bernatchez, Scott E. Woodman
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The regulation of the distinct intrinsic phenotypic states in melanoma remain poorly characterised. Here, multi-omics analysis for a panel of 68 early passage melanoma cell lines reveals that cancer cell intrinsic transcriptomic programs are associat
Externí odkaz:
https://doaj.org/article/96b59787498043a5a256fe86f8315695
Autor:
Yasunari Fukuda, Matias A. Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M. Lopez, Jared K. Burks, Jeffrey E. Lee, Elizabeth A. Grimm, Dave S. B. Hoon, Suhendan Ekmekcioglu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-11 (2022)
Abstract Soluble forms of receptors play distinctive roles in modulating signal-transduction pathways. Soluble CD74 (sCD74) has been identified in sera of inflammatory diseases and implicated in their pathophysiology; however, few relevant data are a
Externí odkaz:
https://doaj.org/article/140d1bf9c59b46fe8fac11763cb01977
Autor:
Yasunari Fukuda, Matias A. Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M. Lopez, Jared K. Burks, Jeffrey E. Lee, Elizabeth A. Grimm, Dave S. B. Hoon, Suhendan Ekmekcioglu
Publikováno v:
Cell Death and Disease, Vol 13, Iss 5, Pp 1-3 (2022)
Externí odkaz:
https://doaj.org/article/42b64f33aaa74cc386ffcfd4f2939ee4
Autor:
Zhen Ding, Dai Ogata, Jason Roszik, Yong Qin, Sun-Hee Kim, Michael T. Tetzlaff, Alexander J. Lazar, Michael A. Davies, Suhendan Ekmekcioglu, Elizabeth A. Grimm
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
We previously showed that inducible nitric oxide synthase (iNOS) protein expression in melanoma tumor cells is associated with poor patient prognosis. Here, we analyzed the association between iNOS and the oncogenic PI3K-AKT pathway. TCGA data show t
Externí odkaz:
https://doaj.org/article/4e1ad425e82948ee98ee9b883acf629f
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 13, Iss 5, Pp 1105-1108 (2017)
Inducible NO synthase (iNOS/NOS2) protein expression is a well-studied predictor of poor outcome in multiple cancers, and it has also been associated with inflammatory and immunosuppressive processes in the tumor microenvironment. Immunotherapies are
Externí odkaz:
https://doaj.org/article/6a01210d8a1a446f9d9675b706f8d6a8
Autor:
Alexandre Reuben, Christine N. Spencer, Peter A. Prieto, Vancheswaran Gopalakrishnan, Sangeetha M. Reddy, John P. Miller, Xizeng Mao, Mariana Petaccia De Macedo, Jiong Chen, Xingzhi Song, Hong Jiang, Pei-Ling Chen, Hannah C. Beird, Haven R. Garber, Whijae Roh, Khalida Wani, Eveline Chen, Cara Haymaker, Marie-Andrée Forget, Latasha D. Little, Curtis Gumbs, Rebecca L. Thornton, Courtney W. Hudgens, Wei-Shen Chen, Jacob Austin-Breneman, Robert Szczepaniak Sloane, Luigi Nezi, Alexandria P. Cogdill, Chantale Bernatchez, Jason Roszik, Patrick Hwu, Scott E. Woodman, Lynda Chin, Hussein Tawbi, Michael A. Davies, Jeffrey E. Gershenwald, Rodabe N. Amaria, Isabella C. Glitza, Adi Diab, Sapna P. Patel, Jianhua Hu, Jeffrey E. Lee, Elizabeth A. Grimm, Michael T. Tetzlaff, Alexander J. Lazar, Ignacio I. Wistuba, Karen Clise-Dwyer, Brett W. Carter, Jianhua Zhang, P. Andrew Futreal, Padmanee Sharma, James P. Allison, Zachary A. Cooper, Jennifer A. Wargo
Publikováno v:
npj Genomic Medicine, Vol 2, Iss 1, Pp 1-11 (2017)
Melanoma: Tumor differences within a patient may explain heterogeneous responses Patients with metastatic melanoma display molecular and immune differences across tumor sites associated with differential drug responses. A team led by Jennifer Wargo f
Externí odkaz:
https://doaj.org/article/95f4f8da81aa4220b7ea3fea4b7af4b6
Autor:
Paramahamsa Maturu, Devin Jones, E. Cristy Ruteshouser, Qianghua Hu, Joseph M Reynolds, John Hicks, Nagireddy Putluri, Suhendan Ekmekcioglu, Elizabeth A. Grimm, Chen Dong, Willem W Overwijk
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 3, Pp 237-249 (2017)
Wilms' tumors (WT), which accountfor 6% of all childhood cancers, arise from dysregulated differentiation of nephrogenic progenitor cells from embryonic kidneys. Though there is an improvement in the prognosis of WT, still 10% of patients with WT die
Externí odkaz:
https://doaj.org/article/d824de115c3146d0bbf686f6bf306a11
Supplementary Methods, Figure Legends, Table Legends from Dual Roles of RNF2 in Melanoma Progression
Autor:
Lynda Chin, Jason Ernst, Alexander J. Lazar, Suhendan Ekmekcioglu, James W. Horner, Timothy P. Heffernan, Denai R. Milton, Michelle C. Barton, Elizabeth A. Grimm, Dong Yang, Amiksha Shah, Jacob B. Axelrad, Maura Williams, Neha S. Samant, Sneha Sharma, Emily Z. Keung, Chang-Jiun Wu, Petko Fiziev, Lawrence N. Kwong, Kadir C. Akdemir, Kunal Rai
This file contains supplementary methods, supplementary figure legends, supplementary table legends and supplementary references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7095d0bbb71a789f1d7eb2dcfbc2adc3
https://doi.org/10.1158/2159-8290.22530408.v1
https://doi.org/10.1158/2159-8290.22530408.v1
Autor:
Lynda Chin, Jason Ernst, Alexander J. Lazar, Suhendan Ekmekcioglu, James W. Horner, Timothy P. Heffernan, Denai R. Milton, Michelle C. Barton, Elizabeth A. Grimm, Dong Yang, Amiksha Shah, Jacob B. Axelrad, Maura Williams, Neha S. Samant, Sneha Sharma, Emily Z. Keung, Chang-Jiun Wu, Petko Fiziev, Lawrence N. Kwong, Kadir C. Akdemir, Kunal Rai
Supplementary Figure 1. Western blots. Supplementary Figure 2. Graphs showing tumor volume from mice following intradermal injection of (A) HMEL-BRAF^V600E cells, (B) WM115 cells, (C) 1205 Lu cells, and (D) pMEL-NRAS^G12D overexpressing GFP, RNF2 wil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15e831788ff1e3285cfe08fa304cd37
https://doi.org/10.1158/2159-8290.22530411.v1
https://doi.org/10.1158/2159-8290.22530411.v1
Autor:
Lynda Chin, Jason Ernst, Alexander J. Lazar, Suhendan Ekmekcioglu, James W. Horner, Timothy P. Heffernan, Denai R. Milton, Michelle C. Barton, Elizabeth A. Grimm, Dong Yang, Amiksha Shah, Jacob B. Axelrad, Maura Williams, Neha S. Samant, Sneha Sharma, Emily Z. Keung, Chang-Jiun Wu, Petko Fiziev, Lawrence N. Kwong, Kadir C. Akdemir, Kunal Rai
Description of states in 45-state chromatin state model.This table describes the biological annotation of each chromatin state in 50-state chromatin model from HMEL-BRAFV600E cells from ChromHMM program.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6811ad484f0cf089b3c3445a0c0077fb
https://doi.org/10.1158/2159-8290.22530399.v1
https://doi.org/10.1158/2159-8290.22530399.v1