Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Elizabeth A, Folly"'
Autor:
Helen E. Sanger, Adrian J. Mogg, Laura-Jayne Ball, Lisa M. Broad, Daniel Ursu, Olivera Grubisha, Cara L. Ruble, Elizabeth A. Folly, Jessica L Sorge
Publikováno v:
British Journal of Pharmacology. 171:2631-2644
Background and Purpose Transient receptor potential vanilloid subtype 3 (TRPV3) is implicated in nociception and certain skin conditions. As such, it is an attractive target for pharmaceutical research. Understanding of endogenous TRPV3 function and
Autor:
Adrian J. Mogg, Elizabeth A. Folly, C E J Mill, J P Beck, Lisa M. Broad, Ruth E. Beattie, Maria-Jesus Blanco
Publikováno v:
British Journal of Pharmacology. 168:1015-1029
Background and Purpose Evidence suggests that phosphorylation of TRPV1 is an important component underlying its aberrant activation in pathological pain states. To date, the detailed pharmacology of diverse TRPV1 receptor agonists and antagonists has
Autor:
Chunjin Ding, Beverly A. Heinz, Mirko Moroni, Andrew Caerwyn Williams, Lisa M. Broad, Elizabeth A. Folly, Ruud Zwart, Adrian J. Mogg, Emanuele Sher, Anna L. Carbone, Deyi Zhang, Isabel Bermudez
Publikováno v:
Molecular Pharmacology. 73:1838-1843
Sazetidine-A has been recently proposed to be a "silent desensitizer" of alpha4beta2 nicotinic acetylcholine receptors (nAChRs), implying that it desensitizes alpha4beta2 nAChRs without first activating them. This unusual pharmacological property of
Autor:
Gordon I. McPhie, Ruud Zwart, Elizabeth A. Folly, Emanuele Sher, Laura R. Johnson, Ruth E. Beattie, Kathy H. Pearson, Stephen G. Volsen, Emma Bell, Non M. Evans, Giovanni Benedetti, Lisa M. Broad, Suchira Bose, Neil S. Millar, Peter J. Craig
Publikováno v:
European Journal of Pharmacology. 502:31-40
A chimera comprising the N-terminal region of the human alpha7 nicotinic acetylcholine receptor, fused to the transmembrane/C-terminal domains of the mouse serotonin 5-HT3 receptor, was constructed. Injection of the chimera cDNA into Xenopus oocytes,
Autor:
Carmen Martin-Ruiz, Margaret L. Bauman, Elaine K. Perry, Elizabeth A. Folly, Jenny Merrit, Robert H. Perry, Gary L. Wenk, Portia E. Iversen, Stephen G. Volsen, M. Lee, Jennifer A. Court
Publikováno v:
The American journal of psychiatry. 158(7)
Measures of cholinergic transmitter activity were investigated in patients with autism because of reported neuropathological abnormalities in cholinergic nuclei in the basal forebrain.Levels of cholinergic enzyme and receptor activity were measured i