Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Elizabeth, Conibear"'
Autor:
Garrett Strawn, Ryan W K Wong, Barry P Young, Michael Davey, Corey Nislow, Elizabeth Conibear, Christopher J R Loewen, Thibault Mayor
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract The yeast Saccharomyces cerevisiae is widely used as a host cell for recombinant protein production due to its fast growth, cost-effective culturing, and ability to secrete large and complex proteins. However, one major drawback is the relat
Externí odkaz:
https://doaj.org/article/16bae354f68542b19615ff87f578b08a
Autor:
Idil Ulengin-Talkish, Matthew A. H. Parson, Meredith L. Jenkins, Jagoree Roy, Alexis Z. L. Shih, Nicole St-Denis, Gergo Gulyas, Tamas Balla, Anne-Claude Gingras, Péter Várnai, Elizabeth Conibear, John E. Burke, Martha S. Cyert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Calcineurin — the Ca2+ regulated phosphatase and target of immunosuppressants — regulates GPCR-mediated phospholipid signaling at the plasma membrane. Here the authors show that CNAβ1 (a poorly studied isoform of the calcineurin catalytic subuni
Externí odkaz:
https://doaj.org/article/3b894a2338db4ca0a402fda3dfce006b
Autor:
Inês Gomes Castro, Shawn P Shortill, Samantha Katarzyna Dziurdzik, Angela Cadou, Suriakarthiga Ganesan, Rosario Valenti, Yotam David, Michael Davey, Carsten Mattes, Ffion B Thomas, Reut Ester Avraham, Hadar Meyer, Amir Fadel, Emma J Fenech, Robert Ernst, Vanina Zaremberg, Tim P Levine, Christopher Stefan, Elizabeth Conibear, Maya Schuldiner
Publikováno v:
eLife, Vol 11 (2022)
Actively maintained close appositions between organelle membranes, also known as contact sites, enable the efficient transfer of biomolecules between cellular compartments. Several such sites have been described as well as their tethering machineries
Externí odkaz:
https://doaj.org/article/4cc2e0fc3a4b4ef1b1b469ec271c520b
Autor:
Shawn P Shortill, Mia S Frier, Ponthakorn Wongsangaroonsri, Michael Davey, Elizabeth Conibear
Publikováno v:
eLife, Vol 11 (2022)
Membrane trafficking pathways perform important roles in establishing and maintaining the endosomal network. Retrograde protein sorting from the endosome is promoted by conserved SNX-BAR-containing coat complexes including retromer which enrich cargo
Externí odkaz:
https://doaj.org/article/524f6fd2df9b46bb9566764a00f11abe
Publikováno v:
Contact, Vol 1 (2018)
Membrane contact sites are regulated through the controlled recruitment of constituent proteins. Yeast vacuolar protein sorting 13 (Vps13) dynamically localizes to membrane contact sites at endosomes, vacuoles, mitochondria, and the endoplasmic retic
Externí odkaz:
https://doaj.org/article/bb3922f5d3e344c29880a2b560119a98
Autor:
Angela Cadou, Samantha Katarzyna Dziurdzik, Shawn P Shortill, Inês Gomes Castro, Suriakarthiga Ganesan, Rosario Valenti, Yotam David, Michael Davey, Carsten Mattes, Ffion B Thomas, Reut Ester Avraham, Hadar Meyer, Amir Fadel, Emma J Fenech, Robert Ernst, Vanina Zaremberg, Tim P Levine, Christopher Stefan, Elizabeth Conibear, Maya Schuldiner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1033ed07e881ada897b967e03057f16e
https://doi.org/10.7554/elife.74602.sa2
https://doi.org/10.7554/elife.74602.sa2
Autor:
Elizabeth Conibear, Tamas Balla, Péter Várnai, Meredith L. Jenkins, Anne-Claude Gingras, Matthew A.H. Parson, Nicole St-Denis, John E. Burke, Idil Ulengin-Talkish, Gergo Gulyas, Alexis Z. L. Shih, Martha S. Cyert, Jagoree Roy
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Calcineurin, the conserved protein phosphatase and target of immunosuppressants, is a critical mediator of Ca2+ signaling. Here, to discover calcineurin-regulated processes we examined an understudied isoform, CNAβ1. We show that unlike canonical cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a204e7e2597f48da04fba147a872fb8
https://doi.org/10.1096/fasebj.2022.36.s1.r6277
https://doi.org/10.1096/fasebj.2022.36.s1.r6277
Publikováno v:
Human Molecular Genetics
Mutations in each of the four human VPS13 (VPS13A–D) proteins are associated with distinct neurological disorders: chorea-acanthocytosis, Cohen syndrome, early-onset Parkinson’s disease and spastic ataxia. Recent evidence suggests that the differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697c6be52a50bc430da752f7b5068e09
http://europepmc.org/articles/PMC7068118
http://europepmc.org/articles/PMC7068118
Autor:
Angela Cadou, Samantha Katarzyna Dziurdzik, Shawn P Shortill, Inês Gomes Castro, Suriakarthiga Ganesan, Rosario Valenti, Yotam David, Michael Davey, Carsten Mattes, Ffion B Thomas, Reut Ester Avraham, Hadar Meyer, Amir Fadel, Emma J Fenech, Robert Ernst, Vanina Zaremberg, Tim P Levine, Christopher Stefan, Elizabeth Conibear, Maya Schuldiner
Publikováno v:
eLife
Actively maintained close appositions between organelle membranes, also known as contact sites, enable the efficient transfer of biomolecules between cellular compartments. Several such sites have been described as well as their tethering machineries
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4508f23048424ed8708f530b64002823