Dabigatran for Treatment and Secondary Prevention of Venous Thromboembolism in Pediatric Congenital Heart Disease

Autor: Manuela Albisetti, Igor Tartakovsky, Jacqueline Halton, Lisa Bomgaars, Elizabeth Chalmers, Lesley G. Mitchell, Matteo Luciani, Ildar Nurmeev, Kirill Gorbatikov, Corinna Miede, Martina Brueckmann, Leonardo R. Brandão

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 4 (2024)

Background Congenital heart disease (CHD) is common in children and associated with greater risk of thrombotic complications. Management of these complications with standard‐of‐care treatment is suboptimal for these children. Methods and Results

Externí odkaz: https://doaj.org/article/b638d23a24724bb0bb3666d450e82e48

Routine management, healthcare resource use and patient and carer‐reported outcomes of patients with transfusion‐dependent β‐thalassaemia in the United Kingdom: A mixed methods observational study

Autor: Farrukh Shah, Paul Telfer, Mark Velangi, Shivan Pancham, Robert Wynn, Sally Pollard, Elizabeth Chalmers, Jonathan Kell, Angela M. Carter, Joe Hickey, Clark Paramore, Minesh Jobanputra, Kate Ryan

Publikováno v: eJHaem, Vol 2, Iss 4, Pp 738-749 (2021)

Abstract Objectives We evaluated routine healthcare management, clinical status and patient‐ and carer‐reported outcomes in UK paediatric and adult patients with transfusion‐dependent β‐thalassaemia (TDT). Methods A multi‐centre, observati

Externí odkaz: https://doaj.org/article/0e55f29da6df4ad2860859fcc13a2116

Edoxaban for Thromboembolism Prevention in Pediatric Patients With Cardiac Disease

Autor: Michael A. Portman, Jeffrey P. Jacobs, Jane W. Newburger, Felix Berger, Michael A. Grosso, Anil Duggal, Ben Tao, Neil A. Goldenberg, Matthew Brothers, Bradley Marino, Charles Canter, Mark Law, Nguyenvu Nguyen, Charlie Sang, Kristin Shimano, Dipankar Gupta, Michael Portman, Derek Williams, Lauren Glass, Charles Sperrazza, Steven Herold, Ruchira Garg, Mark Vranicar, Sawsan Awad, Alfred Asante-Korang, Colleen Druzgal, Caroline Ozment, Kamill Del Toro, Ferran Roses, Christian Jux, Verena Gravenhorst, Ulrich Schweigmann, Mihir Bhatt, Christine Sabapathy, Nagib Dahdah, Dototea Bartonicek, Gerald Tulzer, Elena Basargina, Tatiana Zvereva, Tatiana Pertels, Irina Plotnikova, S.E.G.U.E.L.A. Pierre-Emmanuel, Pascal Amedro, Dulac Yves, Damien BONNET, Paola Saraco, Alessandro Rimini, Valerii Digtiar, Margaryta Gonchar, Tetyana Kryuchko, Olga Yablon, Varinder Singh Bedi, Jashvant Patel, Monjori Mitra, Jacek Kusa, Kowalczyk Domagala, László KÖRNYEI, Csaba BERECZKI, László ABLONCZY, Vivianne Aviva Levitas, David Mishali, Shoshana Revel-Vilk, Dan Harlev, Hatice Ilgen Sasmaz, Namik Yasar Ozbek, Sule Unal, Türkan Patıroglu, Baris Malbora, Hasan Agin, Zeynep Karakas, Ramazan Kaan Kavakli, Elizabeth Chalmers, Frances Bu'Lock, Piers Daubeney, Hala Hamza, Mohamed Badr, Mohsen Elalfy, Ahmed Mansour, Hoda Hassab, Ayman Sabry, Linda Daou, Fadi Bitar

Publikováno v: Journal of the American College of Cardiology. 80:2301-2310

Standard of care (SOC) anticoagulation for thromboembolism (TE) prevention in children with cardiac disease includes low molecular weight heparins or vitamin K antagonists. Limited data exists for alternate use of direct oral anticoagulants in childr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc9820f0798cc8f0ac3ae00a75a96f1
https://doi.org/10.1016/j.jacc.2022.09.031

Children and adults successfully comprehend subject-only sentences online.

Autor: Pooja Paul, Jayden Ziegler, Elizabeth Chalmers, Jesse Snedeker

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0209670 (2019)

In many offline studies, children show selectively better comprehension of sentences with the focus particle only when it modifies the object argument (Jane only ate an apple) than they do when it modifies the subject argument (Only Jane ate an apple

Externí odkaz: https://doaj.org/article/fa24eb02bf904d658faa4e1aedfcee8c

Anticoagulant Effects of Dabigatran on Coagulation Laboratory Parameters in Pediatric Patients: Combined Data from Five Pediatric Clinical Trials

Autor: Lesley G. Mitchell, Daniel Röshammar, Fenglei Huang, Manuela Albisetti, Leonardo R. Brandão, Lisa Bomgaars, Elizabeth Chalmers, Jacqueline Halton, Matteo Luciani, David Joseph, Igor Tartakovsky, Savion Gropper, Martina Brueckmann

Publikováno v: Thrombosis and haemostasis. 122(9)

Background Dabigatran etexilate, a direct oral thrombin inhibitor, is approved to treat venous thromboembolism (VTE) in both adults and children. Objectives This population analysis characterized relationships between dabigatran total plasma concentr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b45305695eff62e547c5b8812ddcd25b
https://pubmed.ncbi.nlm.nih.gov/35909257