Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Elizabeth, Calzada"'
Autor:
Carlos J Nogueras‐Ortiz, Erden Eren, Pamela Yao, Elizabeth Calzada, Christopher Dunn, Olga Volpert, Francheska Delgado‐Peraza, Maja Mustapic, Alexey Lyashkov, F Javier Rubio, Michael Vreones, Lesley Cheng, Yang You, Andrew F Hill, Tsuneya Ikezu, Erez Eitan, Edward J Goetzl, Dimitrios Kapogiannis
Publikováno v:
Journal of Extracellular Vesicles, Vol 13, Iss 6, Pp n/a-n/a (2024)
Abstract Isolation of neuron‐derived extracellular vesicles (NDEVs) with L1 Cell Adhesion Molecule (L1CAM)‐specific antibodies has been widely used to identify blood biomarkers of CNS disorders. However, full methodological validation requires de
Externí odkaz:
https://doaj.org/article/6df60f35215049c1aa20aedfca6fedc4
Autor:
Christopher E. Ramsden, Daisy Zamora, Mark S. Horowitz, Jahandar Jahanipour, Elizabeth Calzada, Xiufeng Li, Gregory S. Keyes, Helen C. Murray, Maurice A. Curtis, Richard M. Faull, Andrea Sedlock, Dragan Maric
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-31 (2023)
Abstract In sporadic Alzheimer’s disease (sAD) specific regions, layers and neurons accumulate hyperphosphorylated Tau (pTau) and degenerate early while others remain unaffected even in advanced disease. ApoER2-Dab1 signaling suppresses Tau phospho
Externí odkaz:
https://doaj.org/article/e3736605578a4ed187f90e071e5def20
Autor:
Elizabeth Calzada, Erica Avery, Pingdewinde N. Sam, Arnab Modak, Chunyan Wang, J. Michael McCaffery, Xianlin Han, Nathan N. Alder, Steven M. Claypool
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Phosphatidylethanolamine (PE) is synthesized by four separate pathways, although surprisingly, perturbing mitochondrial PE synthesis compromises mitochondrial function. Here, the authors show that mitochondrial PE synthesis is required for Complex II
Externí odkaz:
https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b19
Autor:
Pingdewinde N. Sam, Elizabeth Calzada, Michelle Grace Acoba, Tian Zhao, Yasunori Watanabe, Anahita Nejatfard, Jonathan C. Trinidad, Timothy E. Shutt, Sonya E. Neal, Steven M. Claypool
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102196- (2021)
Summary: Phosphatidylethanolamine (PE) made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the en
Externí odkaz:
https://doaj.org/article/5673c62c20164817be88580fb0fa27b1
Autor:
Christopher E. Ramsden, Gregory S. Keyes, Elizabeth Calzada, Mark S. Horowitz, Daisy Zamora, Jahandar Jahanipour, Andrea Sedlock, Fred E. Indig, Ruin Moaddel, Dimitrios Kapogiannis, Dragan Maric
Publikováno v:
J Alzheimers Dis
Background: Sporadic Alzheimer’s disease (sAD) lacks a unifying hypothesis that can account for the lipid peroxidation observed early in the disease, enrichment of ApoE in the core of neuritic plaques, hallmark plaques and tangles, and selective vu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d3b70b9e6fdca425b2f6499496daf2
https://doi.org/10.3233/jad-220071
https://doi.org/10.3233/jad-220071
Autor:
Daisy Zamora, Mark S. Horowitz, Andrea B. Sedlock, Dragan Maric, Elizabeth Calzada, Gregory S. Keyes, Christopher E. Ramsden, Dimitrios Kapogiannis, Jahandar Jahanipour, Fred E. Indig, Ruin Moaddel
Structured AbstractBackgroundSporadic Alzheimer’s disease (sAD) lacks a unifying hypothesis that can account for the lipid peroxidation observed early in the disease, enrichment of ApoE in the central core of neuritic plaques, the hallmark plaques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e4aad3bfea6658cbf3839934bbd63d4
https://doi.org/10.1101/2021.07.05.21259649
https://doi.org/10.1101/2021.07.05.21259649
Autor:
J. Michael McCaffery, Steven M. Claypool, Arnab Modak, Chunyan Wang, Elizabeth Calzada, Erica Avery, Pingdewinde N. Sam, Xianlin Han, Nathan N. Alder
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f92c4d0e750afafa67e8a4f7d8d5facc
https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b19
https://doaj.org/article/ca5c4b849f3d4bd9ac4625fe961b2b19
Autor:
Yasunori Watanabe, Timothy E. Shutt, Sonya E. Neal, Pingdewinde N. Sam, Anahita Nejatfard, Tian Zhao, Jonathan C. Trinidad, Steven M. Claypool, Elizabeth Calzada, Michelle Grace Acoba
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102196-(2021)
iScience
iScience
Summary Phosphatidylethanolamine (PE) made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d815f955a613660962a1e79aaf1f194c
http://www.sciencedirect.com/science/article/pii/S2589004221001644
http://www.sciencedirect.com/science/article/pii/S2589004221001644
Autor:
Steven M. Claypool, Sonya E. Neal, Anahita Nejatfard, Michelle Grace Acoba, Elizabeth Calzada, Tian Zhao, Timothy E. Shutt, Pingdewinde N. Sam, Jonathan C. Trinidad, Yasunori Watanabe
SUMMARYPhosphatidylethanolamine made in mitochondria has long been recognized as an important precursor for phosphatidylcholine production that occurs in the endoplasmic reticulum (ER). Recently, the strict mitochondrial localization of the enzyme th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7803c54e0c468bfc671f6a9036dfd636
https://doi.org/10.1101/2020.12.10.416495
https://doi.org/10.1101/2020.12.10.416495
Autor:
Elizabeth, Calzada, Erica, Avery, Pingdewinde N, Sam, Arnab, Modak, Chunyan, Wang, J Michael, McCaffery, Xianlin, Han, Nathan N, Alder, Steven M, Claypool
Publikováno v:
Nature Communications
Of the four separate PE biosynthetic pathways in eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserine decarboxylase (Psd1). Deletion of Psd1 is lethal in mice and compromises mitochondrial function. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b9d3d9db22aca65867282c00885af276
https://pubmed.ncbi.nlm.nih.gov/30926815
https://pubmed.ncbi.nlm.nih.gov/30926815