Emerging roles of apoptotic microtubules during the execution phase of apoptosis

Autor: David Cotán, Mónica Álvarez Córdoba, Marina Villanueva Paz, Juan Garrido Maraver, Mario D. Cordero, Elizabet Alcocer Gómez, Mario de la Mata, Manuel Oropesa Ávila, Alejandro Fernández Vega, Ana Delgado Pavón, José Antonio Sánchez-Alcázar, Isabel de Lavera

Publikováno v: Cytoskeleton. 72:435-446

Apoptosis is a genetically programmed energy-dependent process of cell demise, characterized by specific morphological and biochemical events in which the activation of caspases has an essential role. During apoptosis the cytoskeleton participates ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a9223c24261e9834a5fc46a4092fecea
https://doi.org/10.1002/cm.21254

Erratum to: AMPK Regulation of Cell Growth, Apoptosis, Autophagy, and Bioenergetics

Autor: Marina Villanueva, Paz, David, Cotán, Juan Garrido, Maraver, Manuel, Oropesa-Ávila, Mario, de la Mata, Ana Delgado, Pavón, Isabel, de Lavera, Elizabet Alcocer, Gómez, Mónica Álvarez, Córdoba, José A Sánchez, Alcázar

Publikováno v: Experientia supplementum (2012). 107

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::703965a6a110994dea5a505112648ef4
https://pubmed.ncbi.nlm.nih.gov/27812976

Pharmacological Chaperones and Coenzyme Q10 Treatment Improves Mutant β-Glucocerebrosidase Activity and Mitochondrial Function in Neuronopathic Forms of Gaucher Disease

Autor: Ana Delgado Pavón, Elizabet Alcocer-Gómez, Manuel Oropesa-Ávila, Patricia Ybot-Gonzalez, David Cotán, Mario D. Cordero, Mario de la Mata, Juan Garrido-Maraver, José M. García Fernández, Ana Paula Zaderenko, Marina Villanueva Paz, Carmen Ortiz Mellet, José Antonio Sánchez-Alcázar, Isabel de Lavera

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
Scientific Reports
idUS. Depósito de Investigación de la Universidad de Sevilla

This work is licensed under a Creative Commons Attribution 4.0 International License.
Gaucher disease (GD) is caused by mutations in the GBA1 gene, which encodes lysosomal β -glucocerebrosidase. Homozygosity for the L444P mutation in GBA1 is as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6de052f260609f83475686693ddf106e
https://doi.org/10.1038/srep10903

AMPK As A Target in Rare Diseases

Autor: Galán F, Manuel Oropesa-Ávila, Juan Garrido-Maraver, Isabel de Lavera, David Cotán, Mario de la Mata, Ana Delgado Pavón, José Antonio Sánchez-Alcázar, Elizabet Alcocer-Gómez, Patricia Ybot-Gonzalez, Marina Villanueva Paz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

The AMP-activated protein kinase (AMPK) has emerged as an important sensor of signals that control cellular energy balance in all eukaryotes. AMPK is also involved in fatty acid oxidation, glucose transport, antioxidant defense, mitochondrial biogene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f40294948e01cb3f2d6fcd452b4287
https://pubmed.ncbi.nlm.nih.gov/26758671

Apoptotic cells subjected to cold/warming exposure disorganize apoptotic microtubule network and undergo secondary necrosis

Autor: Juan Garrido-Maraver, Manuel Oropesa-Ávila, José Antonio Sánchez-Alcázar, Ana Delgado Pavón, Mario de la Mata, A. Fernández-Vega, Isabel de Lavera, Mario D. Cordero, Marina Villanueva Paz, David Cotán, Ana Paula Zaderenko, Rafael Lema, Elizabet Alcocer-Gómez

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname

Apoptotic microtubule network (AMN) is organized during apoptosis, forming a cortical structure beneath the plasma membrane which plays a critical role in preserving cell morphology and plasma membrane integrity. The aim of this study was to examine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aefefb3e0ef1e77152e05699d4eb031
https://pubmed.ncbi.nlm.nih.gov/25027509