Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Eliza Wyszko"'
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Agnieszka Fedoruk-Wyszomirska, Marta Orlicka-Płocka, Aleksandra Kowalczyk, Paweł Stączek, Marta Denel-Bobrowska, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Eliza Wyszko, Agnieszka B. Olejniczak
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
The synthesis of carborane-1,8-naphthalimide conjugates and evaluation of their DNA-binding ability and anticancer activity were performed. A series of 4-carboranyl-3-nitro-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, were synthesi
Externí odkaz:
https://doaj.org/article/da14e44f868943c69fa7db724c26232b
Publikováno v:
Antioxidants, Vol 11, Iss 5, p 850 (2022)
Small compounds are a large group of chemicals characterized by various biological properties. Some of them also have antiaging potential, which is mainly attributed to their antioxidant activity. In this study, we examined the antiaging effect of 4-
Externí odkaz:
https://doaj.org/article/0685f2893aac43c99060102bf151f23d
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Małgorzata Giel-Pietraszuk, Eliza Wyszko, Aleksandra Kowalczyk, Paweł Stączek, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 9, p 4598 (2022)
In the present study, we continue our work related to the synthesis of 1,8-naphthalimide and carborane conjugates and the investigation of their anticancer activity and DNA-binding ability. For this purpose, a series of 4-carboranyl-1,8-naphthalimide
Externí odkaz:
https://doaj.org/article/db5721b441274939bf04f71e31ea8206
Autor:
Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Dorota Gurda-Woźna, Paweł Pawelczak, Patrycja Krawczyk, Małgorzata Giel-Pietraszuk, Grzegorz Framski, Tomasz Ostrowski, Eliza Wyszko
Publikováno v:
Antioxidants, Vol 10, Iss 6, p 950 (2021)
Recently, small compound-based therapies have provided new insights into the treatment of glioblastoma multiforme (GBM) by inducing oxidative impairment. Kinetin riboside (KR) and newly designed derivatives (8-azaKR, 7-deazaKR) selectively affect the
Externí odkaz:
https://doaj.org/article/83db956acc3f42ef83ec6d3716681449
Autor:
Sebastian Rykowski, Dorota Gurda-Woźna, Marta Orlicka-Płocka, Agnieszka Fedoruk-Wyszomirska, Małgorzata Giel-Pietraszuk, Eliza Wyszko, Aleksandra Kowalczyk, Paweł Stączek, Andrzej Bak, Agnieszka Kiliszek, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5, p 2772 (2021)
We synthesized a series of novel 3-carboranyl-1,8-naphthalimide derivatives, mitonafide and pinafide analogs, using click chemistry, reductive amination and amidation reactions and investigated their in vitro effects on cytotoxicity, cell death, cell
Externí odkaz:
https://doaj.org/article/0b68f301865e412baf38aa0197ca4f79
Autor:
Daria Różycka, Małgorzata Korycka-Machała, Anna Żaczek, Jarosław Dziadek, Dorota Gurda, Marta Orlicka-Płocka, Eliza Wyszko, Katarzyna Biniek-Antosiak, Wojciech Rypniewski, Agnieszka B. Olejniczak
Publikováno v:
Pharmaceuticals, Vol 13, Iss 12, p 465 (2020)
Tuberculosis (TB) is a severe infectious disease with high mortality and morbidity. The emergence of drug-resistant TB has increased the challenge to eliminate this disease. Isoniazid (INH) remains the key and effective component in the therapeutic r
Externí odkaz:
https://doaj.org/article/f559ab349cd94b44b2a9b590a604cc08
Autor:
Renata Zawirska-Wojtasiak, Agnieszka Fedoruk-Wyszomirska, Paulina Piechowska, Sylwia Mildner-Szkudlarz, Joanna Bajerska, Elżbieta Wojtowicz, Krzysztof Przygoński, Dorota Gurda, Wiktoria Kubicka, Eliza Wyszko
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5245 (2020)
Some studies have ascribed a protective effect against neurodegenerative diseases to the β-carbolines harman (H) and norharman (NH), which occur mostly in coffee and coffee substitutes. We determined the concentrations of β-carbolines and undesirab
Externí odkaz:
https://doaj.org/article/d9a757b62b0e45f992d271bf6981c1b2
Autor:
Adnan Khan Niazi, Etienne Delannoy, Rana Khalid Iqbal, Daria Mileshina, Romain Val, Marta Gabryelska, Eliza Wyszko, Ludivine Soubigou-Taconnat, Maciej Szymanski, Jan Barciszewski, Frédérique Weber-Lotfi, José Manuel Gualberto, André Dietrich
Publikováno v:
Cells, Vol 8, Iss 6, p 583 (2019)
We address here organellar genetic regulation and intercompartment genome coordination. We developed earlier a strategy relying on a tRNA-like shuttle to mediate import of nuclear transgene-encoded custom RNAs into mitochondria in plants. In the pres
Externí odkaz:
https://doaj.org/article/15cda0ed38d34a399f7dcc0a8b708fca
Autor:
Eliza Wyszko, Florian Mueller, Marta Gabryelska, Angelika Bondzio, Mariusz Popenda, Jan Barciszewski, Volker A Erdmann
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86673 (2014)
With the discovery of small non-coding RNA (ncRNA) molecules as regulators for cellular processes, it became intriguing to develop technologies by which these regulators can be applied in molecular biology and molecular medicine. The application of n
Externí odkaz:
https://doaj.org/article/0858e4d9f22e44b18b13cc971bf4ee70
Autor:
Eliza Wyszko, Maciej Szymański, Heinz Zeichhardt, Florian Müller, Jan Barciszewski, Volker A Erdmann
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54741 (2013)
In this manuscript we describe for the first time mirror image catalytic nucleic acids (Spiegelzymes), which hydrolyze sequence specifically L-ribonucleic acid molecules. The mirror image nucleic acid ribozymes designed are based upon the known hamme
Externí odkaz:
https://doaj.org/article/c290c4f65f394210a04de50ec0ca7a7a