Výsledky vyhledávání - "Eliza V. C. Alves-Ferreira"

Akademický článek

Intestinal immune responses to commensal and pathogenic protozoa

Autor: Aline Sardinha-Silva, Eliza V. C. Alves-Ferreira, Michael E. Grigg

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

The physical barrier of the intestine and associated mucosal immunity maintains a delicate homeostatic balance between the host and the external environment by regulating immune responses to commensals, as well as functioning as the first line of def

Externí odkaz: https://doaj.org/article/c05dbe531d65421f8e71917ab3f08473

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Akademický článek

Differential Gene Expression and Infection Profiles of Cutaneous and Mucosal Leishmania braziliensis Isolates from the Same Patient.

Autor: Eliza V C Alves-Ferreira, Juliano S Toledo, Arthur H C De Oliveira, Tiago R Ferreira, Patricia C Ruy, Camila F Pinzan, Ramon F Santos, Viviane Boaventura, David Rojo, Ángelez López-Gonzálvez, Jose C Rosa, Coral Barbas, Manoel Barral-Netto, Aldina Barral, Angela K Cruz

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0004018 (2015)

Leishmaniasis is a complex disease in which clinical outcome depends on factors such as parasite species, host genetics and immunity and vector species. In Brazil, Leishmania (Viannia) braziliensis is a major etiological agent of cutaneous (CL) and m

Externí odkaz: https://doaj.org/article/dbb7bfe6f6ac4a3b9e56b7ede247314e

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Systematic functional analysis of Leishmania protein kinases identifies regulators of differentiation or survival

Autor: Rachel Neish, Juliana B.T. Carnielli, Pegine B. Walrad, Eliza V. C. Alves-Ferreira, Katherine Newling, Charlotte S. Hughes, Barbora Vojtkova, Vincent Geohegan, Petr Volf, Carolina M. C. Catta-Preta, Jeremy C. Mottram, Andrei Mihut, Ben Powell, Laurence G. Wilson, Nicola Baker, Jovana Sadlova, Jon W. Pitchford, Jayanthi Anand

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)

Differentiation between distinct stages is fundamental for the life cycle of intracellular protozoan parasites and for transmission between hosts, requiring stringent spatial and temporal regulation. Here, we apply kinome-wide gene deletion and gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af62b9a87e93b08006a97fc90ba95dd6
https://doi.org/10.1038/s41467-021-21360-8

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PRMT7 regulates RNA-binding capacity and protein stability in Leishmania parasites

Autor: Ewan Parry, Adam Dowle, Tony R. Larson, Pegine B. Walrad, Angela K. Cruz, Tiago R. Ferreira, Michael J. Plevin, Karen Hogg, Foteini Kolokousi, Eliza V. C. Alves-Ferreira

Publikováno v: Nucleic Acids Research

RNA binding proteins (RBPs) are the primary gene regulators in kinetoplastids as transcriptional control is nearly absent, making Leishmania an exceptional model for investigating methylation of non-histone substrates. Arginine methylation is an evol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f919c07f531766204d67656e73c91d2b
https://pubmed.ncbi.nlm.nih.gov/32365184

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Leishmania braziliensis prostaglandin F2α synthase impacts host infection

Autor: Eliza V. C. Alves-Ferreira, Angela K. Cruz, Tiago R. Ferreira, Pegine B. Walrad, Paul M. Kaye

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Parasites & Vectors
Parasites & Vectors, Vol 13, Iss 1, Pp 1-11 (2020)

Background Prostaglandins (PG) are lipid mediators derived from arachidonic acid metabolism. They are involved in cellular processes such as inflammation and tissue homeostasis. PG production is not restricted to multicellular organisms. Trypanosomat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aefd95957b3faf028410bf15b6fd1124

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DiCre-Based Inducible Disruption of Leishmania Genes

Autor: Samuel M. Duncan, Elmarie Myburgh, Jeremy C. Mottram, Eliza V. C. Alves-Ferreira

Publikováno v: Methods in Molecular Biology ISBN: 9781493992096

Conditional gene deletion using dimerizable Cre recombinase (DiCre) is so far the best developed system for the phenotypic analysis of essential genes in Leishmania species. Here, we describe a protocol for the generation of a conditional gene deleti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a57c263ffd938930a1d39c8b4e0082b5
https://doi.org/10.1007/978-1-4939-9210-2_10

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Sclerosing Orbital Inflammation Caused by Leishmania braziliensis

Autor: Antonio Augusto Velasco e Cruz, Patrícia de Cássia Ruy, Fernando Chahud, Angela K. Cruz, Maria Irma Seixas Duarte, Eliza V. C. Alves-Ferreira, Gherusa Milbratz-Moré

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Orbital biopsy of nonspecific orbital inflammation, commonly referred to as “orbital pseudotumor,” typically shows a combination of polyclonal lymphocytes, plasmocytes, leukocytes, macrophages, and variable degrees of collagen deposition. Herein,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f6ebdee200c977e57bcb4bb195de96
https://doi.org/10.4269/ajtmh.16-0389

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Differential Gene Expression and Infection Profiles of Cutaneous and Mucosal Leishmania braziliensis Isolates from the Same Patient

Autor: Ángelez López-Gonzálvez, Manoel Barral-Netto, Patrícia de Cássia Ruy, Viviane Boaventura, Arthur Henrique Cavalcante de Oliveira, Tiago R. Ferreira, Angela K. Cruz, José César Rosa, Aldina Barral, Coral Barbas, Eliza V. C. Alves-Ferreira, Ramon de Freitas Santos, Camila F. Pinzan, Juliano Simões de Toledo, David Rojo

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 9, p e0004018 (2015)
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
PLoS Neglected Tropical Diseases

Background Leishmaniasis is a complex disease in which clinical outcome depends on factors such as parasite species, host genetics and immunity and vector species. In Brazil, Leishmania (Viannia) braziliensis is a major etiological agent of cutaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf3cd131290f58ac78d7ae3be8dbcc98
http://europepmc.org/articles/PMC4569073?pdf=render

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Altered expression of an RBP-associated arginine methyltransferase 7 in Leishmania major affects parasite infection

Autor: Tiago R. Ferreira, Pegine B. Walrad, Barbara Papadopoulou, Tania Paula Aquino Defina, Eliza V. C. Alves-Ferreira, Angela K. Cruz

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Protein arginine methylation is a widely conserved post-translational modification performed by arginine methyltransferases (PRMTs). However, its functional role in parasitic protozoa is still under-explored. The Leishmania major genome encodes five

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12463df3d369c814b357a57d8d243377

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