Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Eliza F. Chakravarty"'
Autor:
Neelakshi R. Jog, Catriona A. Wagner, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Joel M. Guthridge, Judith A. James
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Neutrophil dysregulation, particularly of a low-density subset, is associated with systemic lupus erythematosus (SLE); however, the exact role of normal-density neutrophils in SLE remains unknown. This study compares activation and functional phenoty
Externí odkaz:
https://doaj.org/article/39ecd1bed286419da5fbcca3181ab3fc
Autor:
Rebecca A. Wood, Lauren Guthridge, Emma Thurmond, Carla J. Guthridge, Joseph M. Kheir, Rebecka L. Bourn, Catriona A. Wagner, Hua Chen, Wade DeJager, Susan R. Macwana, Stan Kamp, Rufei Lu, Cristina Arriens, Eliza F. Chakravarty, Aikaterini Thanou, Joan T. Merrill, Joel M. Guthridge, Judith A. James
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100117- (2021)
SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis
Externí odkaz:
https://doaj.org/article/e09b2484b3954ebdbc388b9721939137
Autor:
Joel M. Guthridge, Rufei Lu, Ly Thi-Hai Tran, Cristina Arriens, Teresa Aberle, Stan Kamp, Melissa E. Munroe, Nicolas Dominguez, Timothy Gross, Wade DeJager, Susan R. Macwana, Rebecka L. Bourn, Stephen Apel, Aikaterini Thanou, Hua Chen, Eliza F. Chakravarty, Joan T. Merrill, Judith A. James
Publikováno v:
EClinicalMedicine, Vol 20, Iss , Pp - (2020)
Background: The clinical and pathologic diversity of systemic lupus erythematosus (SLE) hinders diagnosis, management, and treatment development. This study addresses heterogeneity in SLE through comprehensive molecular phenotyping and machine learni
Externí odkaz:
https://doaj.org/article/cb790d3c24634179a0061b64ef7c3855
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Epstein Barr virus (EBV) is a gamma herpes virus associated with certain malignancies and autoimmune diseases. EBV maintains latency in B cells with occasional reactivation, in part by overcoming the host immune response with viral homologs of severa
Externí odkaz:
https://doaj.org/article/0fc77ee608114f239f69090cd92d9426
Autor:
Rufei Lu, Julie M. Robertson, Benjamin F. Bruner, Joel M. Guthridge, Barbara R. Neas, Swapan K. Nath, Jennifer A. Kelly, Kathy L. Moser Sivils, Eliza F. Chakravarty, Diane L. Kamen, Gary S. Gilkeson, Daniel J. Wallace, Michael H. Weisman, R. Hal Scofield, John B. Harley, Judith A. James
Publikováno v:
Autoimmune Diseases, Vol 2012 (2012)
Purpose. This study evaluates high-throughput autoantibody screening and determines associated systemic lupus erythematosus (SLE) clinical features in a large lupus cohort. Methods. Clinical and demographic information, along with serum samples, were
Externí odkaz:
https://doaj.org/article/04308cbc01d54b4880b3f8fd75e99adc
Autor:
Eliza F. Chakravarty
Publikováno v:
International Journal of Rheumatology, Vol 2010 (2010)
Systemic sclerosis (SSc) is a chronic autoimmune disorder characterized by progressive fibrosis of the skin and visceral tissues as well as a noninflammatory vasculopathy. Vascular disease in systemic sclerosis is a major cause of morbidity and morta
Externí odkaz:
https://doaj.org/article/e7fca1c7b8bc4e95900837c4be429056
Autor:
Melissa E. Munroe, Derek Blankenship, Daniele DeFreese, Mohan Purushothaman, Wade DeJager, Susan Macwana, Joel M. Guthridge, Stan Kamp, Nancy Redinger, Teresa Aberle, Eliza F. Chakravarty, Cristina Arriens, Yanfeng Li, Hu Zeng, Kathleen A. McCarthy‐Fruin, Shirley‐Ann Osei‐Onomahm, Uma Thanarajasingam, Judith A. James, Eldon Jupe
Publikováno v:
Arthritis & Rheumatology. 75:723-735
SLE is marked by immune dysregulation linked to varied clinical disease activity. Using a unique longitudinal cohort of SLE patients, this study seeks to identify optimal immune mediators informing an empirically refined Flare Risk Index (FRI) reflec
Autor:
Amanda Moyer, Eliza F. Chakravarty
Publikováno v:
Rheumatic Disease Clinics of North America. 47:441-455
Systemic lupus erythematosus (SLE) is an autoimmune disease that primarily affects women of childbearing age. Pregnancy-related morbidity and mortality are well described in SLE; however, better management of disease activity throughout the disease c
Autor:
Rachel K. Ashby, Elizabeth D. Ferucci, Laura Tarter, Bonnie L. Bermas, Jinoos Yazdany, Francisco M. Marty, Cameron B. Speyer, Brendan M. Everett, Brad H. Rovin, Joseph F. Merola, Candace H. Feldman, Joel S. Weissman, Karen H. Costenbader, Eliza F. Chakravarty, Shamik Bhattacharyya, Sushrut S. Waikar, Rosalind Ramsey-Goldman, Mary Beth F. Son, Aimee O. Hersh
Publikováno v:
Arthritis Care Res (Hoboken)
Objective Individuals with systemic lupus erythematosus (SLE) are at high risk for infections and SLE- and medication-related complications. The present study was undertaken to define a set of SLE-specific adverse outcomes that could be prevented, or
Autor:
Ambre Chambers, R. Hal Scofield, Eliza F. Chakravarty, Martha Tsaliki, Mitali Talsania, Kristi A. Koelsch
Publikováno v:
International Journal of Rheumatic Diseases. 24:120-124
Background Women with systemic lupus erythematosus (SLE) are at risk of premature ovarian failure when treated with cyclophosphamide. This risk is increased when autoimmune thyroid disease is present. We undertook this study to determine whether the