Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eliza A. Gaylord"'
Functional Specialization of Human Salivary Glands and Origins of Proteins Intrinsic to Human Saliva
Autor:
Marie Saitou, Eliza A. Gaylord, Erica Xu, Alison J. May, Lubov Neznanova, Sara Nathan, Anissa Grawe, Jolie Chang, William Ryan, Stefan Ruhl, Sarah M. Knox, Omer Gokcumen
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108402- (2020)
Summary: Salivary proteins are essential for maintaining health in the oral cavity and proximal digestive tract, and they serve as potential diagnostic markers for monitoring human health and disease. However, their precise organ origins remain uncle
Externí odkaz:
https://doaj.org/article/06a14fb0acde454e88472ef286d8730f
Autor:
Ryan M. Samuel, Albertas Navickas, Ashley Maynard, Eliza A. Gaylord, Kristle Garcia, Samyukta Bhat, Homa Majd, Mikayla N. Richter, Nicholas Elder, Daniel Le, Phi Nguyen, Bradley Shibata, Marta Losa Llabata, Licia Selleri, Diana J. Laird, Spyros Darmanis, Hani Goodarzi, Faranak Fattahi
Publikováno v:
bioRxiv
Summary/AbstractThe neural crest (NC) is highly multipotent and generates diverse lineages in the developing embryo. However, spatiotemporally distinct NC populations display differences in fate potential, such as increased gliogenic and parasympathe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed594aa254e5e343e5d5a34952cb6cb5
https://doi.org/10.1101/2023.03.06.531220
https://doi.org/10.1101/2023.03.06.531220
Autor:
Jianlong Li, Sonia Sudiwala, Lionel Berthoin, Seayar Mohabbat, Eliza A. Gaylord, Hanan Sinada, Noel Cruz Pacheco, Jiun Chiun Chang, Oju Jeon, Isabelle M.A. Lombaert, Alison J. May, Eben Alsberg, Chelsea S. Bahney, Sarah M. Knox
Publikováno v:
Science advances, vol 8, iss 51
Salivary gland acinar cells are severely depleted after radiotherapy for head and neck cancer, leading to loss of saliva and extensive oro-digestive complications. With no regenerative therapies available, organ dysfunction is irreversible. Here, usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b482572e7c80de353c930c5a8f8e6d9
https://escholarship.org/uc/item/04h7k3s7
https://escholarship.org/uc/item/04h7k3s7
Autor:
Yael Efraim, Feeling Yu Ting Chen, Ka Neng Cheong, Eliza A. Gaylord, Nancy A. McNamara, Sarah M. Knox
Corneal architecture is essential for vision and is greatly perturbed by the absence of tears due to the highly prevalent disorder dry eye. With no regenerative therapies available, pathological alterations of the ocular surface in response to drynes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939e68e88a708d1ee91b8b4687a9bcba
https://doi.org/10.1101/2022.05.07.491018
https://doi.org/10.1101/2022.05.07.491018
Autor:
Alison J. May, Aaron J. Mattingly, Eliza A. Gaylord, Nathan Griffin, Sonia Sudiwala, Noel Cruz-Pacheco, Elaine Emmerson, Seayar Mohabbat, Sara Nathan, Hanan Sinada, Isabelle M.A. Lombaert, Sarah M. Knox
Publikováno v:
May, A J, Mattingly, A J, Gaylord, E A, Griffin, N, Sudiwala, S, Cruz-Pacheco, N, Emmerson, E, Mohabbat, S, Nathan, S, Sinada, H, Lombaert, I & Knox, S M 2022, ' Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling ', Developmental Cell, vol. 57, no. 22, pp. 2550-2565.e5 . https://doi.org/10.1016/j.devcel.2022.10.011
Acinar cells are the principal secretory units of multiple exocrine organs. A single-cell, layered, lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and coordinate three cellular programs of acinar specification
Autor:
Alison J. May, Aaron J. Mattingly, Eliza A. Gaylord, Noel Cruz-Pacheco, Elaine Emmerson, Sonia Sudiwala, Seayar Mohabbat, Sara Nathan, Hanan Sinada, I Lombaert, Sarah M. Knox
Publikováno v:
SSRN Electronic Journal.
Autor:
Eliza A Gaylord, Ashley R.G. Libby, Todd C. McDevitt, Jessica C Butts, Martina Z Krakora, Nicholas H Elder, David A Joy, Emily A Bulger, Frederico N. Mendoza-Camacho
Publikováno v:
Development
Axial elongation of the neural tube is crucial during mammalian embryogenesis for anterior-posterior body axis establishment and subsequent spinal cord development, but these processes cannot be interrogated directly in humans as they occur post-impl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04701c451bab8e77e4ff0f1b3b1cc1d6
https://europepmc.org/articles/PMC8254868/
https://europepmc.org/articles/PMC8254868/
Autor:
Eliza A Gaylord, Nancy A. McNamara, Sarah M. Knox, Yael Efraim, Feeling Y. T. Chen, Connor Stashko, Ka Neng Cheong
Publikováno v:
J Autoimmun
Autoimmune-mediated dry eye disease is a pathological feature of multiple disorders including Sjogren's syndrome, lupus and rheumatoid arthritis that has a life-long, detrimental impact on vision and overall quality of life. Although late stage disea
Publikováno v:
International journal of molecular sciences, vol 19, iss 11
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3628 (2018)
International Journal of Molecular Sciences
Volume 19
Issue 11
International Journal of Molecular Sciences, Vol 19, Iss 11, p 3628 (2018)
Sjö
gren&rsquo
s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely
gren&rsquo
s syndrome (SS) is characterized by extensive lymphocytic infiltration of the salivary and lacrimal gland (LG), resulting in acinar cell destruction and organ dysfunction. The underlying pathogenesis of SS remains largely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c3dee07803ae93e7e2d439a5ff23731
https://escholarship.org/uc/item/2rq5894t
https://escholarship.org/uc/item/2rq5894t
Autor:
Ophir D. Klein, Noel Cruz-Pacheco, Alison J May, Sarah M. Knox, Marcus O. Muench, Kerstin Seidel, Eliza A Gaylord, Elaine Emmerson, Sara Nathan
Publikováno v:
Development.
The ductal system of the salivary gland has long been postulated to be resistant to radiation-induced damage, a common side effect incurred by head and neck cancer patients receiving radiotherapy. Yet, whether the ducts are capable of regenerating af