Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eliud Sepulveda"'
Autor:
Detlev Mennerich, Priyanka Gupta, Joseph R. Woska, Keith Canada, Danlin Yang, Michael D. Howell, Ernest L. Raymond, Rachel Kroe-Barrett, Gary O. Caviness, Rajkumar Ganesan, Simon Roberts, Kristopher Truncali, Su-Ellen Brown, Jennifer Ahlberg, M. Lamine Mbow, Jay S. Fine, Eliud Sepulveda, Sanjaya Singh, Perez Rocio K, Lee Frego, Kavita Jerath, Christine Grimaldi
Publikováno v:
mAbs
Deficiency of interleukin (IL)-36 receptor antagonist (DITRA) syndrome is a rare autosomal recessive disease caused by mutations in IL36RN. IL-36R is a cell surface receptor and a member of the IL1R family that is involved in inflammatory responses t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1ac8d43b4da06b0ab9d7f67e62ebe3
https://doi.org/10.1080/19420862.2017.1353853
https://doi.org/10.1080/19420862.2017.1353853
Autor:
Michael Franti, Annick Gauthier, Ivo C. Lorenz, Christian L. Jacob, Eliud Sepulveda, Louie Lamorte
Publikováno v:
Virology. 444(1-2):140-147
Infection with human cytomegalovirus (CMV) during pregnancy is the most common cause of congenital disorders, and can lead to severe life-long disabilities with associated high cost of care. Since there is no vaccine or effective treatment, current e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2b895972c49a38daf96fed59cad07f
Autor:
David Presky, Ernest L. Raymond, Catron Katrina Mary, Jeffrey H Hanke, Keith Canada, Lee Frego, Laura Amodeo, Jennifer Ahlberg, Eliud Sepulveda, Rachel Kroe-Barrett, Xiang Zhu, Helen Wu, Yaqin He, Sanjaya Singh
Publikováno v:
mAbs
Herein, we describe the generation and characterization of BI 655066, a novel, highly potent neutralizing anti-interleukin-23 (IL23) monoclonal antibody in clinical development for autoimmune conditions, including psoriasis and Crohn's disease. IL23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c237c2e09bbb003edca42bf1903c800
https://pubmed.ncbi.nlm.nih.gov/25905918
https://pubmed.ncbi.nlm.nih.gov/25905918
Autor:
Eliud Sepulveda, Steven J. Norris, Stacey L. Mueller-Ortiz, Chinnaswamy Jagannath, Margaret Olsen, Audrey Wanger
Publikováno v:
Infection and Immunity. 70:6751-6760
HbhA ofMycobacterium tuberculosisis a multifunctional binding protein, binding to both sulfated sugars such as heparin and to human complement component C3. HbhA may therefore interact with host molecules and/or host cells duringM. tuberculosisinfect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb88ac90c25b941bd3f4ac39dbb98f4
https://doi.org/10.1128/iai.70.12.6751-6760.2002
https://doi.org/10.1128/iai.70.12.6751-6760.2002
Autor:
Jeffrey K. Actor, Martin R. Emanuele, Robert L. Hunter, Chinnaswamy Jagannath, Eliud Sepulveda, Franz Luxem
Publikováno v:
Immunopharmacology. 48:185-197
Mycobacterium avium-intracellulare complex (MAI) are common pathogens of opportunistic infections that are naturally resistant to most antibiotics and develop acquired resistance rapidly. An experimental drug, poloxamer CRL-1072, was found to have tw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf620cf074acaad7373ca4e3877ad9f
https://doi.org/10.1016/s0162-3109(00)00203-4
https://doi.org/10.1016/s0162-3109(00)00203-4
Autor:
Martin R. Emanuele, Chinnaswamy Jagannath, Medea Mshvildadze, Robert L. Hunter, Alice Wells, Amitava Dasgupta, Eliud Sepulveda, Margaret Olsen
Publikováno v:
Life Sciences. 64:1733-1738
Amikacin is an aminoglycoside which is used in the treatment of infection from gram negative bacteria. Amikacin is also used synergistically with penicillin against gram positive cocci. Amikacin cannot be delivered orally probably due to efflux of dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ed1a14e603bdae20de609f1c05622b
https://doi.org/10.1016/s0024-3205(99)00111-3
https://doi.org/10.1016/s0024-3205(99)00111-3
Autor:
Keith Canada, John Edward Park, Joanne van Ryn, Felix Schiele, Tobias Litzenburger, Corey Newsome, Herbert Nar, Eliud Sepulveda
Publikováno v:
Blood. 121(18)
Dabigatran etexilate is a direct thrombin inhibitor and used widely as an anticoagulant for the prevention of stroke in patients with atrial fibrillation. However, anticoagulation therapy can be associated with an increased risk of bleeding. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f77da9a97c38563ec3ee4eac85e0700
https://pubmed.ncbi.nlm.nih.gov/23640994
https://pubmed.ncbi.nlm.nih.gov/23640994
Publikováno v:
Microbial pathogenesis. 28(6)
Mycobacterium tuberculosis (MTB) the causative organism of tuberculosis can remain dormant as a non-culturable organism, reactivate and cause disease in man and animals. There is a need for proof of viability of such organisms in order to understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cde2862c5aa8a3da408a8bde1792a7
https://pubmed.ncbi.nlm.nih.gov/10839970
https://pubmed.ncbi.nlm.nih.gov/10839970