Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elitza M, Deltcheva"'
Autor:
Jason P. Wray, Elitza M. Deltcheva, Charlotta Boiers, Simon Е Richardson, Jyoti Bikram Chhetri, John Brown, Sladjana Gagrica, Yanping Guo, Anuradha Illendula, Joost H. A. Martens, Hendrik G. Stunnenberg, John H. Bushweller, Rachael Nimmo, Tariq Enver
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
The ETV6-RUNX1 chimeric- and native RUNX1-responsive regulomes in paediatric B-acute lymphoblastic leukemia (B-ALL) remain to be characterized. Here, the authors reveal functional antagonism between the two transcription factors predominantly for the
Externí odkaz:
https://doaj.org/article/57a324404a3a49c69acb08a4d571d807
Autor:
Emanuele Azzoni, Vincent Frontera, Giorgio Anselmi, Christina Rode, Chela James, Elitza M. Deltcheva, Atanasiu S. Demian, John Brown, Cristiana Barone, Arianna Patelli, Joe R. Harman, Matthew Nicholls, Simon J. Conway, Edward Morrissey, Sten Eirik W. Jacobsen, Duncan B. Sparrow, Adrian L. Harris, Tariq Enver, Marella F.T.R. de Bruijn
Publikováno v:
Cell Reports, Vol 37, Iss 11, Pp 110103- (2021)
Summary: Hematopoietic stem cells (HSCs) emerge during development from the vascular wall of the main embryonic arteries. The onset of circulation triggers several processes that provide critical external factors for HSC generation. Nevertheless, it
Externí odkaz:
https://doaj.org/article/a6a8f0b3c598425e993d2ab25bd647c9
Autor:
Jason P, Wray, Elitza M, Deltcheva, Charlotta, Boiers, Simon Е, Richardson, Jyoti Bikram, Chhetri, John, Brown, Sladjana, Gagrica, Yanping, Guo, Anuradha, Illendula, Joost H A, Martens, Hendrik G, Stunnenberg, John H, Bushweller, Rachael, Nimmo, Tariq, Enver
Publikováno v:
Nature communications. 13(1)
The ETV6-RUNX1 onco-fusion arises in utero, initiating a clinically silent pre-leukemic state associated with the development of pediatric B-acute lymphoblastic leukemia (B-ALL). We characterize the ETV6-RUNX1 regulome by integrating chromatin immuno