Výsledky vyhledávání - "Elissa M. Downs"

Akademický článek

Early Metabolic Measures Predict Long-term Insulin Independence in Recipients of Total Pancreatectomy and Islet Autotransplantation

Autor: Yoshihide Nanno, MD, PhD, James S. Hodges, PhD, Martin L. Freeman, MD, Guru Trikudanathan, MD, Sarah J. Schwarzenberg, MD, Elissa M. Downs, MD, Karthik Ramanathan, MD, Timothy L. Pruett, MD, Gregory J. Beilman, MD, Srinath Chinnakotla, MD, MCh, Bernhard J. Hering, MD, Melena D. Bellin, MD

Publikováno v: Transplantation Direct, Vol 10, Iss 1, p e1561 (2024)

Background. Although diabetes after total pancreatectomy and islet autotransplantation (TP-IAT) is one of the biggest concerns for TP-IAT recipients and physicians, reliable prediction of post-TP-IAT glycemic control remains unestablished. This study

Externí odkaz: https://doaj.org/article/dc6907de7c9949338aa500140d213e8a

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Portal Vein Thrombosis May Be More Strongly Associated With Islet Infusion Than Extreme Thrombocytosis After Total Pancreatectomy With Islet Autotransplantation

Autor: Solvejg Wastvedt, Melena D. Bellin, Gregory J. Beilman, Martin L. Freeman, James S. Hodges, Elissa M. Downs, Alexander A. Boucher, Varvara A. Kirchner, Sarah Jane Schwarzenberg, Guru Trikudanathan, Timothy L. Pruett, Srinath Chinnakotla, Bernhard J. Hering

Publikováno v: Transplantation. 105:2499-2506

BACKGROUND Total pancreatectomy with islet autotransplantation (TPIAT) involves pancreatectomy, splenectomy, and reinjection of the patient's pancreatic islets into the portal vein. This process triggers a local inflammatory reaction and increase in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdfade09dd7d459d701ccc45d30c98f7
https://doi.org/10.1097/tp.0000000000003624

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Metabolic measures before surgery and long-term diabetes outcomes in recipients of total pancreatectomy and islet autotransplantation

Autor: Sarah Jane Schwarzenberg, Elissa M. Downs, Varvara A. Kirchner, Timothy L. Pruett, Yoshihide Nanno, Bernhard J. Hering, Solvejg Wastvedt, Gregory J. Beilman, Guru Trikudanathan, Martin L. Freeman, Srinath Chinnakotla, Melena D. Bellin

Publikováno v: American Journal of Transplantation. 21:3411-3420

In this single-center, retrospective cohort study, we aimed to elucidate simple metabolic markers or surrogate indices of β-cell function that best predict long-term insulin independence and goal glycemic HbA1c control (HbA1c ≤ 6.5%) after total p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79818ba84870189911a3a97ea3561335
https://doi.org/10.1111/ajt.16573

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Progress in individualizing autologous islet isolation techniques for pediatric islet autotransplantation after total pancreatectomy in children for chronic pancreatitis

Autor: Elissa M. Downs, Melena D. Bellin, Jessica Diaz, David E.R. Sutherland, Bernhard J. Hering, Srinath Chinnakotla, Joshua J. Wilhelm, Appakalai N. Balamurugan, Zachary Swanson, Sarah Jane Schwarzenberg, Marie Cook, James S. Hodges

Publikováno v: American Journal of Transplantation. 21:776-786

Total pancreatectomy with islet autotransplantation is performed to treat chronic pancreatitis in children. Successful islet isolation must address the challenges of severe pancreatic fibrosis and young donor age. We have progressively introduced mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc808f16aa448c5a84ac66b9a354bd27
https://doi.org/10.1111/ajt.16211

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Rapid Infliximab Infusion in the Pediatric Population

Autor: Elissa M. Downs, Boris Sudel, Peter J. Bryan, Richard K. Vehe, Colleen K. Correll, Danielle R. Bullock, Bryce A. Binstadt, Catherine Larson-Nath, Erin J. Munsel, Patricia M. Hobday

Publikováno v: J Pediatr Pharmacol Ther

OBJECTIVES To compare infusion reaction rates between rapid infliximab (REMICADE, Janssen Biotech Inc) infusions and previous standard 2- to 3-hour infusions; additionally, to assess patient satisfaction and reduction in chair time associated with ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9fbed290909c9f9e78b3d1a6dffd82
https://doi.org/10.5863/1551-6776-25.8.705

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Fat-soluble Vitamin Deficiency is Common in Children With Chronic Pancreatitis Undergoing Total Pancreatectomy With Islet Autotransplantation

Autor: Srinath Chinnakotla, Melena D. Bellin, Kendall R. McEachron, Elissa M. Downs, Sarah Jane Schwarzenberg

Publikováno v: Journal of Pediatric Gastroenterology & Nutrition. 72:123-126

The prevalence of fat-soluble vitamin (FSV) deficiency in children undergoing total pancreatectomy with islet autotransplantation (TPIAT) for chronic pancreatitis (CP) is unknown. We quantified FSV deficiency in 100 children (age ≤18) undergoing TP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d271bbfdf49b07c85cf609a6aa25afa
https://doi.org/10.1097/mpg.0000000000002950

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Safety and Clinical Outcomes of Using Low–Molecular-Weight Dextran During Islet Autotransplantation in Children

Autor: Elise F. Northup, Srinath Chinnakotla, Hawa M. Ali, Alexander A. Boucher, Ellen R. Florek, J. J. Wilhelm, Melena D. Bellin, Sarah Jane Schwarzenberg, Elissa M. Downs

Publikováno v: Pancreas. 49:774-780

OBJECTIVES The objective of this study was to evaluate potential safety and clinical benefit of low-molecular-weight dextran (dextran) use in patients undergoing total pancreatectomy with islet auto transplantation (TPIAT). METHODS We evaluated 124 c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5760f561c196b89136f90f2c1a4641
https://doi.org/10.1097/mpa.0000000000001571

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Chronic and Hereditary Pancreatitis

Autor: Elissa M. Downs, Sarah Jane Schwarzenberg

Publikováno v: Textbook of Pediatric Gastroenterology, Hepatology and Nutrition ISBN: 9783030800673
Textbook of Pediatric Gastroenterology, Hepatology and Nutrition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bf9a4624313b82558f0c07393f1c2000
https://doi.org/10.1007/978-3-030-80068-0_35

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Early use of continuous glucose monitoring in children and adolescents after total pancreatectomy with islet autotransplantation

Autor: Neha Potlapalli, Varvara A. Kirchner, Kendall R. McEachron, Melena D. Bellin, Sarah Jane Schwarzenberg, Arpana Rayannavar, Gregory J. Beilman, Srinath Chinnakotla, Elissa M. Downs

Publikováno v: Pediatric diabetesREFERENCES. 22(3)

Background Children undergoing total pancreatectomy with islet autotransplantation (TPIAT) for chronic pancreatitis require intensive insulin therapy early after TPIAT with narrow glycemic targets, which can a present significant care burden. Outpati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba33fdc72250c357f758af70d00300f
https://pubmed.ncbi.nlm.nih.gov/33271633

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