Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Elissa Everton"'
Autor:
Anna R. Smith, Fatima Rizvi, Elissa Everton, Anisah Adeagbo, Susan Wu, Ying Tam, Hiromi Muramatsu, Norbert Pardi, Drew Weissman, Valerie Gouon-Evans
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Primary human hepatocyte (PHH) transplantation is a promising alternative to liver transplantation, whereby liver function could be restored by partial repopulation of the diseased organ with healthy cells. However, currently PHH engraftment
Externí odkaz:
https://doaj.org/article/647d49ee412444f89823e041d316739f
Autor:
Fatima Rizvi, Elissa Everton, Anna R. Smith, Hua Liu, Elizabeth Osota, Mitchell Beattie, Ying Tam, Norbert Pardi, Drew Weissman, Valerie Gouon-Evans
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
When severely or chronically injured, the liver loses ability to regenerate. Here, the authors utilize transient lipid nanoparticle-enclosed HGF and EGF-encoding mRNA delivery to induce hepatocyte proliferation and harness recovery of liver function
Externí odkaz:
https://doaj.org/article/92c5e809fade4febb8867b9abf7c2367
Autor:
Elissa Everton, Fatima Rizvi, Anna Smith, Mitchell Beattie, Ying Tam, Norbert Pardi, Drew Weissman, Valerie Gouon-Evans
Publikováno v:
Bio-Protocol, Vol 11, Iss 19 (2021)
With the recent availability of the SARS-CoV-2 mRNA-based vaccines, public attention has been drawn to this new technology and how it may be applied to other indications. Temporal activation of key hepatic regenerative pathways can induce liver regen
Externí odkaz:
https://doaj.org/article/746e09d624a14493beb234af051c9a85
Autor:
Fatima Rizvi, Elissa Everton, Anna R. Smith, Hua Liu, Elizabeth Osota, Mitchell Beattie, Ying Tam, Norbert Pardi, Drew Weissman, Valerie Gouon-Evans
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/a6db73280a5d4b0d8b7d2140cae4bf48
Autor:
Elissa Everton, Mercedes Del Rio-Moreno, Carlos Villacorta-Martin, Pushpinder Singh Bawa, Jonathan Lindstrom-Vautrin, Hiromi Muramatsu, Fatima Rizvi, Anna R. Smith, Ying Tam, Norbert Pardi, Rhonda Kineman, David J. Waxman, Valerie Gouon-Evans
Publikováno v:
bioRxiv
Background and AimsAcetaminophen (APAP) overdose is the leading cause of acute liver failure, with one available treatment, N-acetyl cysteine (NAC). Yet, NAC effectiveness diminishes about ten hours after APAP overdose, urging for therapeutic alterna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a005a87698cc25a2897b9bdef04429dd
https://europepmc.org/articles/PMC10153200/
https://europepmc.org/articles/PMC10153200/
Autor:
Valerie Gouon‐Evans, Fatima Rizvi, Elissa Everton, Anna R. Smith, Tam Ying, Norbert Pardi, Drew Weissman
Publikováno v:
The FASEB Journal. 36
Autor:
Drew Weissman, Norbert Pardi, Mitchell Beattie, Elissa Everton, Ying Tam, Valerie Gouon-Evans, Fatima Rizvi, Anna R. Smith
Publikováno v:
Bio Protoc
With the recent availability of the SARS-CoV-2 mRNA-based vaccines, public attention has been drawn to this new technology and how it may be applied to other indications. Temporal activation of key hepatic regenerative pathways can induce liver regen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28e2a4a96b89caf375d36221ce49118
https://europepmc.org/articles/PMC8517647/
https://europepmc.org/articles/PMC8517647/
Autor:
Elissa Everton, Hua Liu, Valerie Gouon-Evans, Ying Tam, Drew Weissman, Mitchell Beattie, Elizabeth Osota, Norbert Pardi, Anna R. Smith, Fatima Rizvi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Autor:
Mitchell Beattie, Anna R. Smith, Drew Weissman, Elissa Everton, Fatima Rizvi, Hua Liu, Norbert Pardi, Valerie Gouon-Evans, Ying Tam, Elizabeth Osota
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Induction of intrinsic liver regeneration is an unmet need that can be achieved by temporally activating key hepatocyte regenerative pathways. Here, we establish an efficient, safe, non-integrative method to transiently express hepatocyte-growth-fact