Výsledky vyhledávání - "Elisha S. Rusch"

Grading and management of cytokine release syndrome in patients treated with tisagenlecleucel in the JULIET trial

Autor: Elisha S. Rusch, Richard T. Maziarz, David G. Maloney, Junlong Li, Vadim V. Romanov, Frederick L. Locke, James Signorovitch, Stephen J. Schuster

Publikováno v: Blood Advances. 4:1432-1439

Chimeric antigen receptor T-cell (CAR-T) therapy yields durable responses in patients with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). Cytokine release syndrome (CRS) is a CAR-T therapy–related adverse event. To date, clinical tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc675a8860953fdeb23185890b952f9
https://doi.org/10.1182/bloodadvances.2019001304

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Grading of neurological toxicity in patients treated with tisagenlecleucel in the JULIET trial

Autor: James Signorovitch, Frederick L. Locke, Vadim V. Romanov, Elisha S. Rusch, David G. Maloney, Stephen J. Schuster, Richard T. Maziarz, Junlong Li

Publikováno v: Blood Advances. 4:1440-1447

Chimeric antigen receptor-T (CAR-T) cell therapy achieves durable responses in patients with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL), but may be associated with neurological toxicity (NT). We retrospectively assessed differences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6957c38151363c8bd34f5d1f498dc2
https://doi.org/10.1182/bloodadvances.2019001305

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Safety and tolerability of pasireotide long-acting release in acromegaly—results from the acromegaly, open-label, multicenter, safety monitoring program for treating patients who have a need to receive medical therapy (ACCESS) study

Autor: Maria Fleseriu, Eliza B. Geer, Elisha S. Rusch

Publikováno v: Endocrine

Purpose Pasireotide long-acting release is a somatostatin analog that is indicated for treatment of patients with acromegaly. This analysis documents the safety of pasireotide long-acting release in patients with acromegaly enrolled in the ACCESS tri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180748dc34c19a0491f24dccd67ff539
http://europepmc.org/articles/PMC5225222

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Translaminar circuits formed by the pyramidal cells in the superficial layers of cat visual cortex

Autor: German Koestinger, Elisha S. Rusch, Kevan A. C. Martin

Publikováno v: Brain Structure and Function, 223 (4)
Brain Structure & Function

Pyramidal cells in the superficial layers of the neocortex provide a major excitatory projection to layer 5, which contains the pyramidal cells that project to subcortical motor-related targets. Both structurally and functionally rather little is kno

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Synaptic connections formed by patchy projections of pyramidal cells in the superficial layers of cat visual cortex

Autor: Stephan V. Roth, Kevan A. C. Martin, Elisha S. Rusch, German Koestinger

Publikováno v: Brain Structure and Function, 222 (7)
Brain Structure & Function

The present study is the first to describe quantitatively the patterns of synaptic connections made by the patchy network of pyramidal cell axons in the superficial layers of cat V1 in relation to the orientation map. Intrinsic signal imaging of the

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Grading of Neurotoxicity in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (r/r DLBCL) Receiving Tisagenlecleucel Treatment in the JULIET Study

Autor: Vadim V. Romanov, Stephen J. Schuster, Solveig G. Ericson, David G. Maloney, James Signorovitch, Richard T. Maziarz, Frederick L. Locke, Elisha S. Rusch

Publikováno v: Blood. 132:4183-4183

Introduction: CAR-T cell therapy has demonstrated prompt and durable clinical responses in patients with r/r DLBCL, but is associated with unique toxicities such as cytokine-release syndrome (CRS) and neurotoxicity (NT). NT is the second most common

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8c5b2c840cb270fd57f6cf87d31c7756
https://doi.org/10.1182/blood-2018-99-118595

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Consensus Grading of Cytokine Release Syndrome (CRS) in Adult Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (r/r DLBCL) Treated with Tisagenlecleucel on the JULIET Study

Autor: Solveig G. Ericson, Elisha S. Rusch, David G. Maloney, Richard T. Maziarz, Frederick L. Locke, Vadim V. Romanov, James Signorovitch, Stephen J. Schuster

Publikováno v: Blood. 132:4190-4190

Introduction: Autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy achieves rapid and durable responses in patients with r/r DLBCL, although unique potential toxicities require specialized management. Cytokine release syndrome (CRS) is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9954669126b31a6b4c7a542b6a96e6e4
https://doi.org/10.1182/blood-2018-99-113052

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Superficial layer pyramidal cells communicate heterogeneously between multiple functional domains of cat primary visual cortex

Autor: Elisha S. Rusch, Stephan V. Roth, Kevan A. C. Martin

Publikováno v: Nature Communications, 5
Nature Communications

The axons of pyramidal neurons in the superficial layers of the neocortex of higher mammals form lateral networks of discrete clusters of synaptic boutons. In primary visual cortex the clusters are reported to link domains that share the same orienta

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https://hdl.handle.net/20.500.11850/92563

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A biological blueprint for the axons of superficial layer pyramidal cells in cat primary visual cortex

Autor: Elisha S. Rusch, Stephan V. Roth, Kevan A. C. Martin

Publikováno v: Brain Structure and Function, 222 (8)
Brain Structure & Function

Pyramidal cells in the superficial layers of neocortex of higher mammals form a lateral network of axon clusters known as the ‘daisy’ network. The role of these axon clusters remains speculative and we still lack a comprehensive quantitative desc

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