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pro vyhledávání: '"Elisha Hamilton"'
Autor:
Yeon Jae Kim, Elisha Hamilton, William Hannam, Chia-Chi Liu, Rachel Teh, Helge H Rasmussen, Alvaro Garcia
Publikováno v:
Circulation Research. 121
Rationale: Cardiotonic steroids (CTS), such as digoxin, have been used to treat heart failure (HF) for over 200 years. They inhibit the sodium-potassium pump (NKP), and increase cardiac contractility by inhibiting efflux of sodium through the pump (
Autor:
Maged, William, Jimmy, Vien, Elisha, Hamilton, Alvaro, Garcia, Henning, Bundgaard, Ronald J, Clarke, Helge H, Rasmussen
Publikováno v:
The Journal of physiology. 565(Pt 3)
Nitric oxide (NO) affects the membrane Na(+)-K(+) pump in a tissue-dependent manner. Stimulation of intrinsic pump activity, stimulation secondary to NO-induced Na(+) influx into cells or inhibition has been reported. We used the whole-cell patch cla