Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Elisha, Hughes"'
Autor:
Timothy Simmons, Elisha Hughes, Dmitry Pruss, Matthew Kucera, Benjamin Roa, Thaddeus Judkins, Thomas Slavin, Victor Abkevich, Ryan Hoff, Srikanth Jammulapati, Susanne Wagner, Dale Muzzey, Jerry Lanchbury, Alexander Gutin
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100945- (2024)
Externí odkaz:
https://doaj.org/article/2a67aed1d3124d9ab3923d655c8d87fd
Autor:
Brent Mabey, Elisha Hughes, Braden Probst, Holly Pederson, Timothy Simmons, Brian Morris, Brooke Hullinger, Susan Domchek, Charis Eng, Monique Gary, Jennifer Klemp, Semanti Mukherjee, Joseph Vijai, Kenneth Offit, Olufunmilayo Olopade, Sandhya Pruthi, Allison Kurian, Mark Robson, Pat Whitworth, Susanne Wagner, Jerry Lanchbury, Thomas Slavin, Alexander Gutin
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100082- (2023)
Externí odkaz:
https://doaj.org/article/32bed194eef5483cbef9262feee8f2d8
Autor:
Mary B. Daly, Eric Rosenthal, Shelly Cummings, Ryan Bernhisel, John Kidd, Elisha Hughes, Alexander Gutin, Stephanie Meek, Thomas P. Slavin, Allison W. Kurian
Publikováno v:
Breast Cancer Research and Treatment. 199:617-626
Purpose Young age at breast cancer (BC) diagnosis and family history of BC are strongly associated with high prevalence of pathogenic variants (PVs) in BRCA1 and BRCA2 genes. There is limited evidence for such associations with moderate/high penetran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9826af76fcd1b941cd98c8dccc86c02d
https://doi.org/10.1007/s10549-023-06946-8
https://doi.org/10.1007/s10549-023-06946-8
Autor:
Elisha Hughes, Ryan Bernhisel, Holly Pederson, Braden Probst, Timothy Simmons, Susanne Wagner, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M. Domchek, Charis Eng, Judy Garber, Monique Gary, Ora K. Gordon, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Funmi Olopade, Joseph Vijai, Jeffrey N. Weitzel, Pat Whitworth, Lamis Yehia, Allison Kurian, Mark Robson, Thomas P. Slavin, Alexander Gutin, Jerry S. Lanchbury
Publikováno v:
Cancer Research. 82:P2-11
Background: Polygenic risk scores (PRS) have been shown to provide genomically informed breast cancer risk assessment in both carriers and non-carriers of predisposing genetic mutations. Risk stratification is further improved by combining a PRS with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ef9fee751958f718fc65ce0d7ffe404
https://doi.org/10.1158/1538-7445.sabcs21-p2-11-21
https://doi.org/10.1158/1538-7445.sabcs21-p2-11-21
Autor:
Allison W. Kurian, Johnathan M. Lancaster, Nanda A. Singh, Eric T. Rosenthal, Katie Larson, Elisha Hughes, Ryan Bernhisel, Michael J. Hall
Supplemental Tables 1-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2db2d056158725d5affc43fc57a0c66
https://doi.org/10.1158/1940-6207.22534658
https://doi.org/10.1158/1940-6207.22534658
Autor:
Allison W. Kurian, Johnathan M. Lancaster, Nanda A. Singh, Eric T. Rosenthal, Katie Larson, Elisha Hughes, Ryan Bernhisel, Michael J. Hall
Pathogenic variants (PVs) in ATM are relatively common, but the scope and magnitude of risk remains uncertain. This study aimed to estimate ATM PV cancer risks independent of family cancer history. This analysis included patients referred for heredit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9952faabead5ea2209f138b2a8f96d08
https://doi.org/10.1158/1940-6207.c.6547595.v1
https://doi.org/10.1158/1940-6207.c.6547595.v1
Autor:
Robert Brown, Jerry S. Lanchbury, Hani Gabra, Nadeem Siddiqui, Liz-Anne Lewsley, Xinxue Liu, Jennifer H. Steel, Mona El-Bahrawy, Alexander Gutin, Michael Perry, Christopher Neff, Krystal Brown, Elisha Hughes, Kirsten M. Timms, James Paul, Euan A. Stronach
The current study evaluated three biomarkers [homologous recombination deficiency (HRD), tumor BRCA1/2 (tBRCA) mutations, and CCNE1 copy-number variation (CNV)] in ovarian tumors from patients enrolled on the SCOTROC4 clinical trial for associations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::403af0f1740cae947c1b7ba5bb996251
https://doi.org/10.1158/1541-7786.c.6541371
https://doi.org/10.1158/1541-7786.c.6541371
Autor:
Robert Brown, Jerry S. Lanchbury, Hani Gabra, Nadeem Siddiqui, Liz-Anne Lewsley, Xinxue Liu, Jennifer H. Steel, Mona El-Bahrawy, Alexander Gutin, Michael Perry, Christopher Neff, Krystal Brown, Elisha Hughes, Kirsten M. Timms, James Paul, Euan A. Stronach
Supplemental Figure 1. Flow of patients and samples through study Supplemental Figure 2. Receiver operating curve (ROC) for HRD as a predictor of CA125 response in the HGSOC subset. Supplementary Table 1. Clinical characteristics and patient outcome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100565dfec09b57a158da7e8e3c81c80
https://doi.org/10.1158/1541-7786.22516485.v1
https://doi.org/10.1158/1541-7786.22516485.v1
Autor:
Emad A. Rakha, Ian O. Ellis, Ralf Kronenwett, Jerry S. Lanchbury, Thomas P. Slavin, Alexander Gutin, Susanne Wagner, Jennifer Doedt, Vanessa Kuhl, Gabriella Savvidou, Ioanna Zouvani, Georgios Georgiou, Eleni Kakouri, Stephanie Meek, Braden Probst, Elisha Hughes, Ryan Bernhisel, Timothy Simmons, Michael S. Toss, Yiola Marcou, Anastasia Constantinidou
Supplementary Figure from Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39505d06a8de1caac6a15ca6417f5430
https://doi.org/10.1158/1078-0432.22489697.v1
https://doi.org/10.1158/1078-0432.22489697.v1
Autor:
Emad A. Rakha, Ian O. Ellis, Ralf Kronenwett, Jerry S. Lanchbury, Thomas P. Slavin, Alexander Gutin, Susanne Wagner, Jennifer Doedt, Vanessa Kuhl, Gabriella Savvidou, Ioanna Zouvani, Georgios Georgiou, Eleni Kakouri, Stephanie Meek, Braden Probst, Elisha Hughes, Ryan Bernhisel, Timothy Simmons, Michael S. Toss, Yiola Marcou, Anastasia Constantinidou
Supplementary Data from Clinical Validation of EndoPredict in Pre-Menopausal Women with ER-Positive, HER2-Negative Primary Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff343797b1c484d316d37f454558e17
https://doi.org/10.1158/1078-0432.22489700
https://doi.org/10.1158/1078-0432.22489700