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Synthesis and Pharmacological Evaluation of Novel 2,3,4,5-tetrahydro[1,3]diazepino[1,2- a ]benzimidazole Derivatives as Promising Anxiolytic and Analgesic Agents.

Autor: Maltsev DV; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia.; Laboratory of Experimental Pharmacology, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Spasov AA; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia.; Laboratory of Experimental Pharmacology, Volgograd Medical Scientific Center, 400131 Volgograd, Russia.; Laboratory for Information Technology in Pharmacology and Computer Modeling of Drugs for Reasearch Center of Innovative Medicines, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Vassiliev PM; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia.; Laboratory for Information Technology in Pharmacology and Computer Modeling of Drugs for Reasearch Center of Innovative Medicines, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Skripka MO; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia.; Laboratory of Experimental Pharmacology, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Miroshnikov MV; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia., Kochetkov AN; Laboratory for Information Technology in Pharmacology and Computer Modeling of Drugs for Reasearch Center of Innovative Medicines, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Eliseeva NV; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia.; Laboratory of Experimental Pharmacology, Volgograd Medical Scientific Center, 400131 Volgograd, Russia., Lifanova YV; Department of Pharmacology and Bioinformatics, Volgograd State Medical University, 400131 Volgograd, Russia., Kuzmenko TA; Research Institute of Physical and Organic Chemistry, Laboratory of organic synthesis, Southern Federal University, 344090 Rostov-on-Don, Russia., Divaeva LN; Research Institute of Physical and Organic Chemistry, Laboratory of organic synthesis, Southern Federal University, 344090 Rostov-on-Don, Russia., Morkovnik AS; Research Institute of Physical and Organic Chemistry, Laboratory of organic synthesis, Southern Federal University, 344090 Rostov-on-Don, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 06; Vol. 26 (19). Date of Electronic Publication: 2021 Oct 06.

[Study of the functional significance of polymorphic loci of the LOXL1 gene associated with glaucoma according to genome-wide studies (in silico analysis)].

Autor: Eliseeva NV; Belgorod State National Research University, Belgorod, Russia., Ponomarenko IV; Belgorod State National Research University, Belgorod, Russia., Churnosov MI; Belgorod State National Research University, Belgorod, Russia.

Publikováno v: Vestnik oftalmologii [Vestn Oftalmol] 2021; Vol. 137 (5), pp. 22-30.