Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Elise S Bales"'
Autor:
Daniel N Frank, Elise S Bales, Jenifer Monks, Matthew J Jackman, Paul S MacLean, Diana Ir, Charles E Robertson, David J Orlicky, James L McManaman
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0131944 (2015)
Obesity and its co-morbidities, such as fatty liver disease, are increasingly prevalent worldwide health problems. Intestinal microorganisms have emerged as critical factors linking diet to host physiology and metabolic function, particularly in the
Externí odkaz:
https://doaj.org/article/d49c0896db2e4aa08f775c588c6ab526
Autor:
Jessica L Saben, Elise S Bales, Matthew R Jackman, David Orlicky, Paul S MacLean, James L McManaman
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e98066 (2014)
Maternal metabolic and nutrient trafficking adaptations to lactation differ among lean and obese mice fed a high fat (HF) diet. Obesity is thought to impair milk lipid production, in part, by decreasing trafficking of dietary and de novo synthesized
Externí odkaz:
https://doaj.org/article/c1fc1094bdcb454383c5e9c1d85703ee
Autor:
Amanda E Crunk, Jenifer Monks, Aya Murakami, Matthew Jackman, Paul S Maclean, Mark Ladinsky, Elise S Bales, Shannon Cain, David J Orlicky, James L McManaman
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67631 (2013)
Cytoplasmic lipid droplets (CLD) are organelle-like structures that function in neutral lipid storage, transport and metabolism through the actions of specific surface-associated proteins. Although diet and metabolism influence hepatic CLD levels, ho
Externí odkaz:
https://doaj.org/article/6aee8997dce543e3bd1d5d247608a1fc
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 8, Pp 1482-1500 (2018)
Mice lacking perilipin-2 (Plin2-null) are resistant to obesity, insulin resistance, and fatty liver induced by Western or high-fat diets. In the current study, we found that, compared with WT mice on Western diet, Plin2-null adipose tissue was more i
Externí odkaz:
https://doaj.org/article/7d82077ec6ff4db6bd5f9eaaac75ac55
Autor:
Hannah M. Hicks, Nikita Pozdeyev, Sharon B. Sams, Umarani Pugazhenthi, Elise S. Bales, Marie-Claude Hofmann, Logan R. McKenna, Rebecca E. Schweppe
Publikováno v:
Molecular Cancer Research.
Mutations in BRAF are common in advanced papillary and anaplastic thyroid cancer (PTC and ATC). However, BRAF-mutant PTC patients currently lack therapies targeting this pathway. Despite the approved combination of BRAF and MEK1/2 inhibition for pati
Autor:
Alanna Mayberry, Eduardo Antônio Donadi, Melissa L Ledezma, David J. Orlicky, Jacob Calhoun, Bruna Cristina Bertol, Elise S. Bales, Sharon Sams, Jena D. French, Bryan R. Haugen
Publikováno v:
Thyroid
Background: Combination therapy with lenvatinib plus programmed death-1 (PD-1) immune checkpoint blockades (ICBs) is under investigation in many solid tumors, including thyroid cancer. Lenvatinib is known to reduce angiogenesis and may overturn the i
Autor:
Joshua Johnson, So‐Youn Kim, Peter Ka Sam, Rengasamy Asokan, Evelyn Llerena Cari, Elise S. Bales, Thanh‐Ha Luu, Lauren Perez, Amanda N. Kallen, Liesl Nel‐Themaat, Alex J. Polotsky, Miriam D. Post, David J. Orlicky, Kimberly R. Jordan, Benjamin G. Bitler
Publikováno v:
American journal of reproductive immunology (New York, N.Y. : 1989).
Immune cell trafficking and surveillance within the ovary and fallopian tube are thought to impact fertility and also tumorigenesis in those organs. However, little is known of how native cells of the ovary and fallopian tube interact with resident i
Autor:
Lorna G. Moore, Anna G. Euser, Katharine K. Nelson, Kori Baker, Colleen G. Julian, Julie A. Houck, Ramón A. Lorca, Louise C. Laurent, Christopher J. Matarazzo, Elise S. Bales, Mana M. Parast, Mariko Horii
Publikováno v:
Placenta. 104:267-276
Introduction High-altitude (>2500 m) residence augments the risk of intrauterine growth restriction (IUGR) and preeclampsia likely due, in part, to uteroplacental hypoperfusion. Previous genomic and transcriptomic studies in humans and functional stu
Autor:
James L. McManaman, Elise S. Bales, David J. Orlicky, Matthew Jackman, Paul S. MacLean, Shannon Cain, Amanda E. Crunk, Ayla Mansur, Christine E. Graham, Thomas A. Bowman, Andrew S. Greenberg
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 5, Pp 1346-1359 (2013)
The cytoplasmic lipid droplet (CLD) protein perilipin-2 (Plin2) is expressed in multiple nonadipose tissues, where it is thought to play a role in regulating their lipid storage properties. However, the extent to which Plin2 functions in nutrient uti
Externí odkaz:
https://doaj.org/article/4f340467484b405ea7c8616f0a966032
Autor:
Ramón A. Lorca, Lorna G. Moore, Colleen G. Julian, Julie A. Houck, Sydney L. Lane, Elise S. Bales, Alexandrea S. Doyle
Publikováno v:
J Physiol
KEY POINTS Pregnancy at high altitude is associated with a greater incidence of fetal growth restriction due, in part, to lesser uterine artery blood flow. AMP-activated protein kinase (AMPK) activation vasodilates arteries and may increase uterine a