Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elise N. Engquist"'
Autor:
Elise N. Engquist, Anna Greco, Leo A.B. Joosten, Baziel G.M. van Engelen, Christopher R.S. Banerji, Peter S. Zammit
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109947- (2024)
Summary: The routine need for myonuclear turnover in skeletal muscle, together with more sporadic demands for hypertrophy and repair, are performed by resident muscle stem cells called satellite cells. Muscular dystrophies are characterized by muscle
Externí odkaz:
https://doaj.org/article/41dea0aec9644f16875e162cd583eb18
Autor:
Philipp Heher, Massimo Ganassi, Adelheid Weidinger, Elise N. Engquist, Johanna Pruller, Thuy Hang Nguyen, Alexandra Tassin, Anne-Emilie Declèves, Kamel Mamchaoui, Christopher R.S. Banerji, Johannes Grillari, Andrey V. Kozlov, Peter S. Zammit
Publikováno v:
Redox Biology, Vol 51, Iss , Pp 102251- (2022)
Facioscapulohumeral muscular dystrophy (FSHD) is characterised by descending skeletal muscle weakness and wasting. FSHD is caused by mis-expression of the transcription factor DUX4, which is linked to oxidative stress, a condition especially detrimen
Externí odkaz:
https://doaj.org/article/d7a7b235468647e692ef74d6d5e95b8e
Autor:
Nadav Sharon, Jordan Vanderhooft, Juerg Straubhaar, Jonas Mueller, Raghav Chawla, Quan Zhou, Elise N. Engquist, Cole Trapnell, David K. Gifford, Douglas A. Melton
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2281-2291.e5 (2019)
Summary: In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exoge
Externí odkaz:
https://doaj.org/article/7d2705e92a034b8e973c491a0c58005c
Autor:
Peter S. Zammit, Elise N. Engquist
Publikováno v:
Journal of Neuromuscular Diseases
The resident stem cell for skeletal muscle is the satellite cell. On the 50th anniversary of its discovery in 1961, we described the history of skeletal muscle research and the seminal findings made during the first 20 years in the life of the satell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02cf062186cfbb076091422b4f25c9ec
http://europepmc.org/articles/PMC8673500
http://europepmc.org/articles/PMC8673500
Autor:
Philipp Heher, Massimo Ganassi, Adelheid Weidinger, Elise N. Engquist, Johanna Pruller, Thuy Hang Nguyen, Alexandra Tassin, Anne-Emilie Declèves, Kamel Mamchaoui, Christopher R.S. Banerji, Johannes Grillari, Andrey V. Kozlov, Peter S. Zammit
Publikováno v:
Redox biology. 51
Facioscapulohumeral muscular dystrophy (FSHD) is characterised by descending skeletal muscle weakness and wasting. FSHD is caused by mis-expression of the transcription factor DUX4, which is linked to oxidative stress, a condition especially detrimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcd4cc3bcef68833d549bd10ca8a5898
https://pubmed.ncbi.nlm.nih.gov/35248827
https://pubmed.ncbi.nlm.nih.gov/35248827
Autor:
James F. Markmann, Riley K Driscoll, Douglas A. Melton, Elise N. Engquist, Mark C. Poznansky, Ruxandra F. Sîrbulescu, Madeline F.E. Penson, Jenny J L Cao, Marinko Sremac, David A. Alagpulinsa, Timothy Brauns
Publikováno v:
American Journal of Transplantation. 19:1930-1940
Pancreatic β-cell replacement by islet transplantation for the treatment of type 1 diabetes (T1D) is currently limited by donor tissue scarcity and the requirement for lifelong immunosuppression. The advent of in vitro differentiation protocols for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef57f65292c6c5495bfd387ded899027
https://doi.org/10.1111/ajt.15308
https://doi.org/10.1111/ajt.15308
Autor:
Henry L. Bushnell, George Harb, Felicia W. Pagliuca, Elad Sintov, Mads Gürtler, Aubrey L. Faust, Quinn P. Peterson, Douglas A. Melton, Jennifer H. R. Kenty, Adrian Veres, Elise N. Engquist, Yeh Chuin Poh
Publikováno v:
Nature. 569:368-373
In vitro differentiation of human stem cells can produce pancreatic β-cells; the loss of this insulin-secreting cell type underlies type 1 diabetes. Here, as a step towards understanding this differentiation process, we report the transcriptional pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64bcb41ab0bcd5d44ec18211f97c4b5
https://doi.org/10.1038/s41586-019-1168-5
https://doi.org/10.1038/s41586-019-1168-5
Autor:
Jeffrey C. Davis, Douglas A. Melton, José Rivera-Feliciano, Elise N. Engquist, Aharon Helman, Christine M. Langston
Publikováno v:
Current Protocols in Stem Cell Biology
Our laboratory and others have developed protocols to generate glucose‐responsive stem cell–derived β cells in vitro. The cells resulting from these protocols could supplement or replace the use of human cadaveric islets for cell‐based therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52b3a50c77618342f716dbfc61ea464e
https://pubmed.ncbi.nlm.nih.gov/31756031
https://pubmed.ncbi.nlm.nih.gov/31756031
Autor:
Juerg R. Straubhaar, Jonas Mueller, Raghav Chawla, Cole Trapnell, Jordan Vanderhooft, Nadav Sharon, Douglas A. Melton, David K. Gifford, Elise N. Engquist, Quan Zhou
Publikováno v:
Elsevier
Cell Reports, Vol 27, Iss 8, Pp 2281-2291.e5 (2019)
Cell Reports, Vol 27, Iss 8, Pp 2281-2291.e5 (2019)
Summary: In vitro differentiation of pluripotent cells into β cells is a promising alternative to cadaveric-islet transplantation as a cure for type 1 diabetes (T1D). During the directed differentiation of human embryonic stem cells (hESCS) by exoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58b2c69c83fe19c01db180e95a17332
https://europepmc.org/articles/PMC6933053/
https://europepmc.org/articles/PMC6933053/
Autor:
Douglas A. Melton, Elise N. Engquist, Alexander M. Tsankov, Sundari Chetty, Kathy O. Lui, Elie K. Mehanna
Publikováno v:
The Journal of Cell Biology
Inhibiting Src activity through genetic suppression or the small molecule inhibitor PP1 enhances the differentiation capacity of human pluripotent stem cells across all germ layers, and these improvements are preceded by activation of the retinoblast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2f6c6d5fcb0a01bd409aabda24cc30a
https://pubmed.ncbi.nlm.nih.gov/26416968
https://pubmed.ncbi.nlm.nih.gov/26416968