Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Elise M. Messier"'
Autor:
Ellen M. Unterwald, Dhanendra Tomar, Elise M. Messier, Muniswamy Madesh, Mark O. Aksoy, Robert J. Mason, Gerard J. Criner, John W. Elrod, Toby K. Eisenstein, Karim Bahmed, Loukmane Karim, Hannah Simborio, Chih-Ru Lin, Steven G. Kelsen, Beata Kosmider
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
The alveolus participates in gas exchange, which can be impaired by environmental factors and toxins. There is an increase in using electronic cigarettes (e-cigarettes); however, their effect on human primary alveolar epithelial cells is unknown. Hum
Autor:
Karim Bahmed, Hsin Yao Tang, Jiusheng Lin, Tessa Andrews, Samia Boukhenouna, Robert John Mason, Loukmane Karim, Elise M. Messier, Gerard J. Criner, Robert Powers, Mark A. Wilson, Roger Powell, Chih-Ru Lin, Beata Kosmider, Nichole Reisdorph
Publikováno v:
Cell Death and Disease, Vol 10, Iss 9, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
DJ-1 is a multifunctional protein with cytoprotective functions. It is localized in the cytoplasm, nucleus, and mitochondria. The conserved cysteine residue at position 106 (Cys106) within DJ-1 serves as a sensor of redox state and can be oxidized to
Autor:
Karim Bahmed, Steven G. Kelsen, Chih-Ru Lin, Nathaniel Marchetti, Beata Kosmider, Gerard J. Criner, Roger Powell, Nathaniel Xander, Muniswamy Madesh, Sudhir Bolla, Nichole Reisdorph, Elise M. Messier, Robert J. Mason, Kelly A. Correll, Liudmila Vlasenko
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Emphysema is characterized by alveolar wall destruction induced mainly by cigarette smoke. Oxidative damage of DNA may contribute to the pathophysiology of this disease. We studied the impairment of the non-homologous end joining (NHEJ) repair pathwa
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e26059 (2011)
Cigarette smoke (CS) is a highly complex mixture and many of its components are known carcinogens, mutagens, and other toxic substances. CS induces oxidative stress and cell death, and this cell toxicity plays a key role in the pathogenesis of severa
Externí odkaz:
https://doaj.org/article/8c8798ff8eef4a6f959c62a9fcf1b4e0
Autor:
Steven G. Kelsen, Beata Kosmider, Curt R. Freed, Karim Bahmed, Hong Wei Chu, Rubin M. Tuder, Russell P. Bowler, Wenbo Zhou, Robert J. Mason, Elise M. Messier
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 55:439-449
Cigarette smoke (CS) is a main source of oxidative stress and a key risk factor for emphysema, which consists of alveolar wall destruction. Alveolar type (AT) II cells are in the gas exchange regions of the lung. We isolated primary ATII cells from d
Autor:
Elise M. Messier, Steven R. Kleeberger, Brian J. Day, Beata Kosmider, Robert J. Mason, Hong Wei Chu, Rubin M. Tuder, Russell P. Bowler
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 48:559-567
Emphysema is caused by the cigarette smoke (CS)-induced destruction of alveolar wall septa, and CS is the main risk factor for chronic obstructive pulmonary disease (COPD). To study the mechanisms of response to this insult, we focused on oxidant-ind
Publikováno v:
Experimental Lung Research. 38:363-373
The alveolar surface is covered by an epithelium composed of 2 main cell types: type I and type II cells. Alveolar type II (ATII) cells have a distinct morphology with apical microvilli and characteristic lamellar bodies, which are the intracellular
Autor:
Peter M. Henson, Miglena Prabagar, Sophie L. Gibbings, Elise M. Messier, Robert J. Mason, Tullia C. Bruno, Elodie Segura, William J. Janssen, Gwendalyn J. Randolph, Raivo Kolde, Claudia Jakubzick, A. Nicole Desch, Jill E. Slansky, Jordan Jacobelli, Ramnik J. Xavier, Yoko Ito, Joe Bednarek, Shaikh M. Atif, Donna L. Bratton, Rajni Goyal
Publikováno v:
American journal of respiratory and critical care medicine. 193(6)
The pulmonary mononuclear phagocyte system is a critical host defense mechanism composed of macrophages, monocytes, monocyte-derived cells, and dendritic cells. However, our current characterization of these cells is limited because it is derived lar
Publikováno v:
Cell Death & Disease
Cigarette smoke (CS) is a main risk factor for chronic obstructive pulmonary disease (COPD). Oxidative stress induced by CS causes DNA and lung damage. Oxidant/antioxidant imbalance occurs in the distal air spaces of smokers and in patients with COPD
Publikováno v:
Proceedings of the American Thoracic Society. 9:81-81