Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Elise Leverence"'
Autor:
Swarnendu Tripathi, Nikita R. Dsouza, Angela J. Mathison, Elise Leverence, Raul Urrutia, Michael T. Zimmermann
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 117-127 (2022)
In the current study, we report computational scores for advancing genomic interpretation of disease-associated genomic variation in members of the RAS family of genes. For this purpose, we applied 31 sequence- and 3D structure-based computational sc
Externí odkaz:
https://doaj.org/article/6f4ca9f2edc74280899fa531c6371dee
Autor:
Angela J. Mathison, Romica Kerketta, Thiago Milech de Assuncao, Elise Leverence, Atefeh Zeighami, Guillermo Urrutia, Timothy J. Stodola, Marina Pasca di Magliano, Juan L. Iovanna, Michael T. Zimmermann, Gwen Lomberk, Raul Urrutia
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-29 (2021)
Abstract Background Pancreatic ductal adenocarcinoma initiation is most frequently caused by Kras mutations. Results Here, we apply biological, biochemical, and network biology methods to validate GEMM-derived cell models using inducible KrasG12D exp
Externí odkaz:
https://doaj.org/article/ef75ec357b034f33b2c29cbe89799f9e
Autor:
Michael Zimmermann, Angela Mathison, Xuan Li, Elise Leverence, Davin Jensen, Guadalupe Esparza, Thiago Milech De Assuncao, Brian Smith, Brian Volkman, Gwen Lomberk, Raul Urrutia
The challenge of interpreting novel genetic variations in genomics is widespread. Previous studies have shown the role of KRAS mutations in heritable and somatic conditions, but more genetic variants have been observed than have been characterized. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49151cbe8996604699380bec0d0e3531
https://doi.org/10.21203/rs.3.rs-2883088/v1
https://doi.org/10.21203/rs.3.rs-2883088/v1
Autor:
Gabrielle M. Gentile, Jennifer R. Gamarra, Nichlas M. Engels, R. Eric Blue, Isabel Hoerr, Hannah J. Wiedner, Emma R. Hinkle, Jessica L. Cote, Elise Leverence, Christine A. Mills, Laura E. Herring, Xianming Tan, Jimena Giudice
Publikováno v:
The FASEB Journal. 36
Vesicle-mediated transport is necessary for maintaining cellular homeostasis and proper signaling. The synaptosome-associated protein 23 (SNAP23) is a member of the SNARE protein family and mediates the vesicle docking and membrane fusion steps of se