Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Elise L Townsend"'
Autor:
Christiano R.R. Alves, Marco Petrillo, Rebecca Spellman, Reid Garner, Ren Zhang, Michael Kiefer, Sarah Simeone, Jihee Sohn, Eric J. Eichelberger, Emma Rodrigues, Elizabeth A. Arruda, Elise L. Townsend, Wildon Farwell, Kathryn J. Swoboda
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 524-538 (2021)
This longitudinal cohort study aimed to determine whether circulating neurofilaments (NFs) can monitor response to molecular therapies in newborns with spinal muscular atrophy (SMA; NCT02831296). We applied a mixed-effect model to examine differences
Externí odkaz:
https://doaj.org/article/db25a4904c724193bfc8efc310be8954
Autor:
Katelyn Zumpf, Kristin J. Krosschell, Michael Kiefer, Elise L. Townsend, Sarah D Simeone, Kathryn J. Swoboda, Leah J. Welty
Publikováno v:
Neuromuscul Disord
As trials and treatments for Spinal Muscular Atrophy (SMA) rapidly evolve, understanding the natural history and potential utility of the 10-meter walk/run test (10MWRT) in ambulant individuals is critical. Study aims were to: 1) establish change ove
Autor:
Elizabeth A. Arruda, Eric J. Eichelberger, Elise L. Townsend, Reid Garner, Kiefer Michael C, Ren Zhang, Marco Petrillo, Rebecca Spellman, Sarah D Simeone, Jihee Sohn, Wildon Farwell, Emma Rodrigues, Kathryn J. Swoboda, Christiano R. R. Alves
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 524-538 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
This longitudinal cohort study aimed to determine whether circulating neurofilaments (NFs) can monitor response to molecular therapies in newborns with spinal muscular atrophy (SMA; NCT02831296). We applied a mixed-effect model to examine differences
Publikováno v:
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. 32(3)
Purpose This study examined the degree to which pediatric essential core competencies (ECCs) are meeting their intended purpose to provide guidance to pediatric educators in professional physical therapy (PT) education programs and to determine facil
Publikováno v:
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. 32(3)
Purpose The purpose of this study was to describe stander use in a natural history cohort of drug therapy-naive children with spinal muscular atrophy (SMA) who are not walking and identify factors associated with consistent stander use. Methods Data
Publikováno v:
J Neurotrauma
The Glasgow Outcome Scale, Pediatric Revision (GOSE-P) is an assessment of “global outcome” designed as a developmentally appropriate version of the Glasgow Outcome Scale-Extended for use in clinical trials of children with traumatic brain injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de53915530af8f06b4ccf6b8682343e
https://europepmc.org/articles/PMC7339019/
https://europepmc.org/articles/PMC7339019/
Publikováno v:
Phys Occup Ther Pediatr
Traumatic brain injury (TBI) can impair physical function in children. The NIH Toolbox Motor Battery (NIHTB-M) was designed to be a brief assessment of physical function, but no studies have examined its use in children with TBI. This study aims to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe8f9372f825b74eb68be116555625d
https://europepmc.org/articles/PMC7657981/
https://europepmc.org/articles/PMC7657981/
Publikováno v:
Journal of neuromuscular diseases. 7(3)
Background The impact of nusinersen therapy on outcomes in adults with Spinal Muscular Atrophy (SMA) remains uncertain. Objective To demonstrate whether nusinersen therapy, at currently prescribed doses, can stabilize or improve motor function in adu
Autor:
Brunhilde Wirth, Mary K. Schroth, Sandra P. Reyna, Kathryn J. Swoboda, Ren Zhe Zhang, Charles B. Scott, Kristin J. Krosschell, Thomas O. Crawford, Elise L. Townsend, Priya S. Kishnani, John T. Kissel, Bernie LaSalle, Jürgen-Christoph von Kleist-Retzow, Edward C. Smith, Thomas W. Prior, Sarah D Simeone, Louise R. Simard, Barbara Hero, Guy D'Anjou, Bakri Elsheikh, Gyula Acsadi, Ai Sakonju
Publikováno v:
Muscle & Nerve. 57:193-199
Introduction:To explore safety and therapeutic potential of L-carnitine and valproic acid (VPA) in infants with spinal muscular atrophy (SMA). Methods: Open-label phase 2 multicenter trial of L-carnitine and VPA in infants with SMA type I with retros
Autor:
Elise L. Townsend, Michael J Kiefer
Publikováno v:
Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association. 30(4)