Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Elise Krespan"'
1
Akademický článek
Selective whole-genome amplification reveals population genetics of Leishmania braziliensis directly from patient skin biopsies.
Autor: Olivia A Pilling, João L Reis-Cunha, Cooper A Grace, Alexander S F Berry, Matthew W Mitchell, Jane A Yu, Clara R Malekshahi, Elise Krespan, Christina K Go, Cláudia Lombana, Yun S Song, Camila F Amorim, Alexsandro S Lago, Lucas P Carvalho, Edgar M Carvalho, Dustin Brisson, Phillip Scott, Daniel C Jeffares, Daniel P Beiting
Publikováno v: PLoS Pathogens, Vol 19, Iss 3, p e1011230 (2023)
In Brazil, Leishmania braziliensis is the main causative agent of the neglected tropical disease, cutaneous leishmaniasis (CL). CL presents on a spectrum of disease severity with a high rate of treatment failure. Yet the parasite factors that contrib
Externí odkaz: https://doaj.org/article/737717bbee8b47e590ec22cd8859a3a4
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2
Akademický článek
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection.
Autor: Elisabet Bjanes, Reyna Garcia Sillas, Rina Matsuda, Benjamin Demarco, Timothée Fettrelet, Alexandra A DeLaney, Opher S Kornfeld, Bettina L Lee, Eric M Rodríguez López, Daniel Grubaugh, Meghan A Wynosky-Dolfi, Naomi H Philip, Elise Krespan, Dorothy Tovar, Leonel Joannas, Daniel P Beiting, Jorge Henao-Mejia, Brian C Schaefer, Kaiwen W Chen, Petr Broz, Igor E Brodsky
Publikováno v: PLoS Pathogens, Vol 17, Iss 10, p e1009967 (2021)
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates plasma membrane pores that mediate cell lysis and IL-1 cytokine release.
Externí odkaz: https://doaj.org/article/8d9976e5a9e54adc98393333ee0b5aa5
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5
Inflammatory monocytes promote pyogranuloma formation to counteract Yersinia blockade of host defense
Autor: Daniel Sorobetea, Rina Matsuda, Stefan T. Peterson, James P. Grayczyk, Indira Rao, Elise Krespan, Matthew Lanza, Charles-Antoine Assenmacher, Daniel Beiting, Enrico Radaelli, Igor Brodsky
Granulomas are organized immune cell aggregates that form in response to chronic infection or antigen persistence. Yersinia pseudotuberculosis (Yp) blocks innate inflammatory signaling and phagocytosis, inducing formation of neutrophil-rich pyogranul
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0d215d434c8f0508e9cf2f5fcdaa9084
https://doi.org/10.1101/2022.02.06.479204
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6
Mutations Affecting HVO_1357 or HVO_2248 Cause Hypermotility in Haloferax volcanii, Suggesting Roles in Motility Regulation
Autor: Mechthild Pohlschroder, Michiyah Collins, Aime Bienfait Igiraneza, Michael L. Dyall-Smith, Heather Schiller, Daniel P. Beiting, Friedhelm Pfeiffer, Simisola Afolayan, Elise Krespan
Publikováno v: Genes, Vol 12, Iss 58, p 58 (2021)
Genes
Volume 12
Issue 1
Motility regulation plays a key role in prokaryotic responses to environmental stimuli. Here, we used a motility screen and selection to isolate hypermotile Haloferax volcanii mutants from a transposon insertion library. Whole genome sequencing revea
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b28fcdea3d149cfa3fb9e266490eef
https://www.mdpi.com/2073-4425/12/1/58
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7
Genetic targeting of Card19 is linked to disrupted NINJ1 expression, impaired cell lysis, and increased susceptibility to Yersinia infection
Autor: Alexandra DeLaney, Opher S. Kornfeld, Bettina L. Lee, Daniel P. Beiting, Eric M. Rodriguez Lopez, Petr Broz, Timothée Fettrelet, Jorge Henao-Mejia, Daniel Grubaugh, Elisabet Bjanes, Benjamin Demarco, Reyna Garcia Sillas, Elise Krespan, Kaiwen W. Chen, Igor E. Brodsky, Meghan A. Wynosky-Dolfi, Dorothy Tovar, Rina Matsuda, Naomi H. Philip, Leonel Joannas, Brian C. Schaefer
Publikováno v: PLoS Pathogens, Vol 17, Iss 10, p e1009967 (2021)
PLoS Pathogens
Plos Pathogens
PLoS pathogens, vol. 17, no. 10, pp. e1009967
Cell death plays a critical role in inflammatory responses. During pyroptosis, inflammatory caspases cleave Gasdermin D (GSDMD) to release an N-terminal fragment that generates plasma membrane pores that mediate cell lysis and IL-1 cytokine release.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d171193d88ea0f866dc6e57f786e24d
https://doaj.org/article/8d9976e5a9e54adc98393333ee0b5aa5
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