Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Elise F. Saunier"'
Autor:
Daphne H. Schoenmakers, Prisca S. Leferink, Adeline Vanderver, Joshua L. Bonkowsky, Ingeborg Krägeloh-Mann, Geneviève Bernard, Enrico Bertini, Ali Fatemi, Brent L. Fogel, Nicole I. Wolf, Donna Skwirut, Allyson Buck, Brett Holberg, Elise F. Saunier-Vivar, Robert Rauner, Hanka Dekker, Pieter van Bokhoven, Menno D. Stellingwerff, Johannes Berkhof, Marjo S. van der Knaap
Publikováno v:
BMC Neurology, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Background The leukodystrophy “Vanishing White Matter” (VWM) is an orphan disease with neurological decline and high mortality. Currently, VWM has no approved treatments, but advances in understanding pathophysiology have led to identifi
Externí odkaz:
https://doaj.org/article/8f4af726592c4d9fb60b72f567204c44
Autor:
Rosemary J. Akhurst, Boris C. Bastian, Ervin H. Epstein, Dan H. Moore, Jesus Perez-Losada, Frederic F. Clermont, Elise F. Saunier, Katie Ridd, Kelly A. Harradine
Supplementary Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d77ef7646c59fbdb3f2b821057c43efd
https://doi.org/10.1158/1078-0432.22440289
https://doi.org/10.1158/1078-0432.22440289
Autor:
Rosemary J. Akhurst, Boris C. Bastian, Ervin H. Epstein, Dan H. Moore, Jesus Perez-Losada, Frederic F. Clermont, Elise F. Saunier, Katie Ridd, Kelly A. Harradine
Purpose: Nonmelanoma skin cancer incidence is enhanced >50-fold in patients taking antirejection drugs (ARD) following organ transplantation. Preclinical studies suggest that ARD treatment increases transforming growth factor-β1 (TGF-β1) levels, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23d1305de02cb2d765327d16e3d66c22
https://doi.org/10.1158/1078-0432.c.6517639.v1
https://doi.org/10.1158/1078-0432.c.6517639.v1
Autor:
Rosemary J. Akhurst, Jonathan M. Yingling, Byron Hann, Angela De Sapio, Minh Thu Luu, David Quigley, Elise F. Saunier, Erin C. Connolly
TGF-β is produced excessively by many solid tumors and can drive malignant progression through multiple effects on the tumor cell and microenvironment. TGF-β signaling pathway inhibitors have shown efficacy in preclinical models of metastatic cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da301134f8d9b0d8816d6197601967e7
https://doi.org/10.1158/0008-5472.c.6502956.v1
https://doi.org/10.1158/0008-5472.c.6502956.v1
Autor:
Rosemary J. Akhurst, Jonathan M. Yingling, Byron Hann, Angela De Sapio, Minh Thu Luu, David Quigley, Elise F. Saunier, Erin C. Connolly
Supplementary Figures 1-6, Tables 1-5 from Outgrowth of Drug-Resistant Carcinomas Expressing Markers of Tumor Aggression after Long-term TβRI/II Kinase Inhibition with LY2109761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d829168a130122fca924dd248525229
https://doi.org/10.1158/0008-5472.22390449.v1
https://doi.org/10.1158/0008-5472.22390449.v1
Autor:
Rosemary J. Akhurst, Jonathan M. Yingling, Byron Hann, Angela De Sapio, Minh Thu Luu, David Quigley, Elise F. Saunier, Erin C. Connolly
Supplementary Figure Legends 1-6, Table Legends 1-5 from Outgrowth of Drug-Resistant Carcinomas Expressing Markers of Tumor Aggression after Long-term TβRI/II Kinase Inhibition with LY2109761
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38354950e295551cdaeb6a1b460c1041
https://doi.org/10.1158/0008-5472.22390452.v1
https://doi.org/10.1158/0008-5472.22390452.v1
Core protocol development for phase 2/3 clinical trials in the leukodystrophy Vanishing White Matter
Autor:
Daphne H. Schoenmakers, Prisca S. Leferink, Adeline Vanderver, Joshua L. Bonkowsky, Ingeborg Krägeloh-Mann, Geneviève Bernard, Enrico Bertini, Ali Fatemi, Brent L. Fogel, Nicole I. Wolf, Donna Skwirut, Allyson Buck, Brett Holberg, Elise F. Saunier-Vivar, Robert Rauner, Hanka Dekker, Pieter Bokhoven, Menno D. Stellingwerff, Johannes Berkhof, Marjo S. Knaap
Background: The leukodystrophy “Vanishing White Matter” (VWM) is an orphan disease with neurological decline and high mortality. Currently, VWM has no approved treatments, but advances in understanding pathophysiology have led to identification o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69f30c2e7a4d2f5a844caa3581f1d468
https://doi.org/10.21203/rs.3.rs-2446334/v1
https://doi.org/10.21203/rs.3.rs-2446334/v1
Autor:
Elise F Saunier, Omar I Vivar, Andrea Rubenstein, Xiaoyue Zhao, Moshe Olshansky, Scott Baggett, Richard E Staub, Mary Tagliaferri, Isaac Cohen, Terence P Speed, John D Baxter, Dale C Leitman
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28333 (2011)
Long-term estrogen deficiency increases the risk of obesity, diabetes and metabolic syndrome in postmenopausal women. Menopausal hormone therapy containing estrogens might prevent these conditions, but its prolonged use increases the risk of breast c
Externí odkaz:
https://doaj.org/article/e1cff8bbcda24860a6082a0bc080acc6
Autor:
Terence P. Speed, Sreenivasan Paruthiyil, Omar I. Vivar, Elise F. Saunier, Candice B. Herber, Isaac Cohen, Dale C. Leitman, Mary Tagliaferri
Publikováno v:
Current Opinion in Pharmacology. 10:629-636
Estrogenic effects are mediated through two estrogen receptor (ER) subtypes, ERα and ERβ. Estrogens are the most commonly prescribed drugs to treat menopausal conditions, but by non-selectively triggering both ERα and ERβ pathways in different ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3a61bc2be4510b61a8c45af7be2fcfc
https://doi.org/10.1016/j.coph.2010.09.009
https://doi.org/10.1016/j.coph.2010.09.009
Publikováno v:
Endocrinology. 151:1662-1667
3,3'-Diindolylmethane (DIM) is a natural compound found in cruciferous vegetables that has antiproliferative and estrogenic activity. However, it is not clear whether the estrogenic effects are mediated through estrogen receptor (ER)alpha, ERbeta, or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63c4af439f1e5fa7ecb65a1b2ceadc92
https://doi.org/10.1210/en.2009-1028
https://doi.org/10.1210/en.2009-1028