Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Elise F. Nassif"'
Autor:
Lucia Martiniova, Serageldin Kamel, Kalevi Kairemo, Robert Benjamin, Neeta Somaiah, Gregory Ravizzini, Elise F. Nassif Haddad
Publikováno v:
Diagnostics, Vol 14, Iss 18, p 2021 (2024)
The purpose of this study was to evaluate the predictive features of baseline F-18-fluorodeoxy-D-glucose positron emission tomography (18F-FDG PET)/computed tomography (CT) parameters in patients with dedifferentiated liposarcomas (DDLPSs) and well-d
Externí odkaz:
https://doaj.org/article/17555ae517f143e8a13f134c52206c6b
Autor:
Lewis F. Nasr, Marianne Zoghbi, Rossana Lazcano, Michael Nakazawa, Andrew J. Bishop, Ahsan Farooqi, Devarati Mitra, Beverly Ashleigh Guadagnolo, Robert Benjamin, Shreyaskumar Patel, Vinod Ravi, Dejka M. Araujo, Andrew Livingston, Maria A. Zarzour, Anthony P. Conley, Ravin Ratan, Neeta Somaiah, Alexander J. Lazar, Christina Roland, Emily Z. Keung, Elise F. Nassif Haddad
Publikováno v:
Cancers, Vol 16, Iss 9, p 1763 (2024)
Background: Undifferentiated pleomorphic sarcomas (UPSs) are amongst the most common subtypes of soft-tissue sarcomas. Few real-world data on the use of immune checkpoint blockade (ICB) in UPS patients and other high-grade pleomorphic STS patients ar
Externí odkaz:
https://doaj.org/article/0a0f97d97b6f4eab81d45c599ea4e336
Autor:
Prapassorn Thirasastr, Heather Lin, Behrang Amini, Wei‐Lien Wang, Jeffrey M. Cloutier, Elise F. Nassif, Emily Z. Keung, Christina L. Roland, Barry Feig, Dejka Araujo, Robert S. Benjamin, Anthony P. Conley, John A. Livingston, Joseph Ludwig, Shreyaskumar Patel, Ravin Ratan, Vinod Ravi, Maria Alejandra Zarzour, Xiao Zhou, Neeta Somaiah
Publikováno v:
Cancer Medicine, Vol 12, Iss 4, Pp 4282-4293 (2023)
Abstract Objective Well‐differentiated (WDLPS) and dedifferentiated liposarcoma (DDLPS) account for the majority of liposarcomas. Although gemcitabine‐docetaxel is used as second‐line treatment in soft tissue sarcomas, its efficacy in WDLPS/DDL
Externí odkaz:
https://doaj.org/article/67794b3693904079b386d4390d2378fa
Publikováno v:
Current Oncology, Vol 30, Iss 2, Pp 2144-2158 (2023)
Significant multidisciplinary scientific effort has been undertaken to understand the heterogeneous family of neoplasms that comprise soft tissue sarcomas. Within this family of neoplasms, outcomes for retroperitoneal sarcomas (RPS) are currently lim
Externí odkaz:
https://doaj.org/article/1af4b4e4c7434bd9b2003322a31252a4
Autor:
Ryan A. Denu, Cissimol P. Joseph, Elizabeth S. Urquiola, Precious S. Byrd, Richard K. Yang, Ravin Ratan, Maria Alejandra Zarzour, Anthony P. Conley, Dejka M. Araujo, Vinod Ravi, Elise F. Nassif Haddad, Michael S. Nakazawa, Shreyaskumar Patel, Wei-Lien Wang, Alexander J. Lazar, Neeta Somaiah
Publikováno v:
Cancers, Vol 16, Iss 9, p 1707 (2024)
Objective: The vast majority of gastrointestinal stromal tumors (GISTs) are driven by activating mutations in KIT, PDGFRA, or components of the succinate dehydrogenase (SDH) complex (SDHA, SDHB, SDHC, and SDHD genes). A small fraction of GISTs lack a
Externí odkaz:
https://doaj.org/article/be2a07dc346f4b1d8386cb2dca2774a8
Autor:
Prapassorn Thirasastr, Thomas L. Sutton, Cissimol P. Joseph, Heather Lin, Behrang Amini, Skye C. Mayo, Dejka Araujo, Robert S. Benjamin, Anthony P. Conley, John A. Livingston, Joseph Ludwig, Shreyaskumar Patel, Ravin Ratan, Vinod Ravi, Maria A. Zarzour, Elise F. Nassif Haddad, Michael S. Nakazawa, Xiao Zhou, Michael C. Heinrich, Neeta Somaiah
Publikováno v:
Cancers, Vol 16, Iss 5, p 904 (2024)
Ripretinib and avapritinib have demonstrated activity in the late-line treatment of gastrointestinal stomal tumors (GISTs). We investigated whether patients previously treated with ripretinib benefit from avapritinib, and vice versa. Patients diagnos
Externí odkaz:
https://doaj.org/article/ff5bb01ba0d7474ca47aa521e68e77e1
Publikováno v:
Cancers, Vol 16, Iss 5, p 938 (2024)
Leiomyosarcoma (LMS) is an aggressive subtype of soft tissue sarcoma that arises from smooth muscle cells, most commonly in the uterus and retroperitoneum. LMS is a heterogeneous disease with diverse clinical and molecular characteristics that have y
Externí odkaz:
https://doaj.org/article/194afa2da81140c782ed461668c4c36b
Autor:
Elise F. Nassif, Cissimol P. Joseph, Rossana Lazcano, Jocelyn T. Joseph, Prapassorn Thirasastr, Alexander J. Lazar, Neeta Somaiah
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
TSC-mutated sarcomas are rare molecular and histologic types of sarcoma. Due to the presence of their specific oncogenic driver mutation, these sarcomas are particularly sensitive to mTOR inhibitors. Recently, nab-sirolimus, an albumin-bound mTOR inh
Externí odkaz:
https://doaj.org/article/a1c63b7a8b594de2b203ca711e8f1b8a
Autor:
Raymond S. Traweek, Brandon M. Cope, Christina L. Roland, Emily Z. Keung, Elise F. Nassif, Derek J. Erstad
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Dedifferentiated liposarcoma (DDLPS) is an aggressive adipogenic cancer with poor prognosis. DDLPS tumors are only modestly sensitive to chemotherapy and radiation, and there is a need for more effective therapies. Genetically, DDLPS is characterized
Externí odkaz:
https://doaj.org/article/4a9fcb3f4db2496ead212f8dd89e9ca6
Autor:
Rossana Lazcano, Carmelia M. Barreto, Ruth Salazar, Fernando Carapeto, Raymond S. Traweek, Cheuk H. Leung, Swati Gite, Jay Mehta, Davis R. Ingram, Khalida M. Wani, Kim-Anh T. Vu, Edwin R. Parra, Wei Lu, Jianling Zhou, Russell G. Witt, Brandon Cope, Prapassorn Thirasastr, Heather Y. Lin, Christopher P. Scally, Anthony P. Conley, Ravin Ratan, J. Andrew Livingston, Alexandra M. Zarzour, Joseph Ludwig, Dejka Araujo, Vinod Ravi, Shreyaskumar Patel, Robert Benjamin, Jennifer Wargo, Ignacio I. Wistuba, Neeta Somaiah, Christina L. Roland, Emily Z. Keung, Luisa Solis, Wei-Lien Wang, Alexander J. Lazar, Elise F. Nassif
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionUndifferentiated pleomorphic sarcoma (UPS) can be associated with a relatively dense immune infiltration. Immune checkpoint inhibitors (anti-PD1, anti-PDL1, and anti-CTLA4) are effective in 20% of UPS patients. We characterize the immune
Externí odkaz:
https://doaj.org/article/0f3178fc4ae44b07859cc53a24e0f97e