Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Elise Dumont"'
Autor:
Natacha Gillet, Elise Dumont
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Oxidatively generated lesions such as 8-oxo-7, 8-dihydroguanine (8-oxoG) on RNA strands constitute a hallmark marker of the oxidative stress in the cell. Poly-C binding protein 1 (PCBP1) is able to specifically recognize severely damaged RNA strands
Externí odkaz:
https://doaj.org/article/bb0192f2b0d44753a4bd6b5ccc2057a4
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2861-2869 (2021)
The combination of several closely spaced DNA lesions, which can be induced by a single radical hit, constitutes a hallmark in the DNA damage landscape and radiation chemistry. The occurrence of such a tandem base lesion gives rise to a strong coupli
Externí odkaz:
https://doaj.org/article/a03e29422340485691d72471b25b5540
Publikováno v:
Molecules, Vol 26, Iss 21, p 6465 (2021)
The 8-oxo-7,8-dihydroguanine, referred to as 8-oxoG, is a highly mutagenic DNA lesion that can provoke the appearance of mismatches if it escapes the DNA Damage Response. The specific recognition of its structural signature by the hOGG1 glycosylase i
Externí odkaz:
https://doaj.org/article/2a0b18d57c224c66949df87606a6d5e6
Autor:
Emmanuelle Bignon, Marco Marazzi, Vanessa Besancenot, Hugo Gattuso, Guillaume Drouot, Christophe Morell, Leif A. Eriksson, Stephanie Grandemange, Elise Dumont, Antonio Monari
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Nonsteroidal 2-arylproprionic acids are widely used, over-the-counter, anti-inflammatory drugs. Photosensitivity is a commonly overlooked adverse effect of these drugs. Based on the combined use of cell viability assays and molecular modelin
Externí odkaz:
https://doaj.org/article/8cd0d36efdfe450e87b6420ae1b08cf9
Autor:
Hong Zhang, Hugo Gattuso, Elise Dumont, Wensheng Cai, Antonio Monari, Christophe Chipot, François Dehez
Publikováno v:
Molecules, Vol 23, Iss 2, p 228 (2018)
DNA is the target of chemical compounds (drugs, pollutants, photosensitizers, etc.), which bind through non-covalent interactions. Depending on their structure and their chemical properties, DNA binders can associate to the minor or to the major groo
Externí odkaz:
https://doaj.org/article/20de9fc1eaf8466db08fdc824998174c
Publikováno v:
The Journal of Physical Chemistry Letters. 14:3199-3207
Publikováno v:
The Journal of Physical Chemistry Letters. 14:1977-1982
Flaviviruses are enveloped viruses causing high public concerns. Their maturation spans several cellular compartments having different pH. Thus, complex control mechanisms are in place to avoid premature maturation. Here we report the dynamical behav
Publikováno v:
Journal of Chemical Information and Modeling. 62:6739-6748
Autor:
Laurent Vial, Julien Leclaire, Florent PERRET, Ivan Huc, Pradeep Kumar Mandal, Elise Dumont, Olivier Cala, Nicolas Vanthuyne, Ana M Belenguer, Christian Duchamp, Titouan Chetot, Emeric Jeamet, Pierre-Thomas Skowron, Benjamin Ourri, Yuan Zhang
The diastereoselective assembly of achiral constituents through a single spontaneous process into complex covalent architectures bearing multiple stereogenic elements still remains a challenge for synthetic chemists. Here, we show that such an extrem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31dbcca0ffb242a8718930216d72822c
https://www.repository.cam.ac.uk/handle/1810/350710
https://www.repository.cam.ac.uk/handle/1810/350710
Autor:
Marco Deiana, José María Andrés Castán, Pierre Josse, Abraha Kahsay, Darío Puchán Sánchez, Korentin Morice, Natacha Gillet, Ranjitha Ravindranath, Ankit Kumar Patel, Pallabi Sengupta, Ikenna Obi, Eva Rodriguez-Marquez, Lhoussain Khrouz, Elise Dumont, Laura Abad Galán, Magali Allain, Bright Walker, Hyun Seo Ahn, Olivier Maury, Philippe Blanchard, Tangui Le Bahers, Daniel Öhlund, Jonas von Hofsten, Cyrille Monnereau, Clément Cabanetos, Nasim Sabouri
Publikováno v:
Nucleic Acids Research.
Photodynamic therapy (PDT) ideally relies on the administration, selective accumulation and photoactivation of a photosensitizer (PS) into diseased tissues. In this context, we report a new heavy-atom-free fluorescent G-quadruplex (G4) DNA-binding PS