Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Elise A. Lucotte"'
Autor:
Elise A. Lucotte, Valdís Björt Guðmundsdóttir, Jacob M. Jensen, Laurits Skov, Moisès Coll Macià, Kristian Almstrup, Mikkel H. Schierup, Agnar Helgason, Kari Stefansson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract A major part of the human Y chromosome consists of palindromes with multiple copies of genes primarily expressed in testis, many of which have been claimed to affect male fertility. Here we examine copy number variation in these palindromes
Externí odkaz:
https://doaj.org/article/31f96b259f3f4c6891a5cb5d0022070c
Autor:
Elise A. Lucotte, Clara Albiñana, Romain Laurent, Claude Bhérer, Genome of the Netherland Consortium, Thomas Bataillon, Bruno Toupance
Publikováno v:
Evolution Letters, Vol 6, Iss 2, Pp 203-216 (2022)
Abstract Sexual dimorphisms are widespread in animals and plants, for morphological as well as physiological traits. Understanding the genetic basis of sexual dimorphism and its evolution is crucial for understanding biological differences between th
Externí odkaz:
https://doaj.org/article/62dbfe83e0444e23b86c0d721a364263
Autor:
Laurits Skov, Daniel F. Gudbjartsson, Margrét Einarsdóttir, Garðar Sveinbjörnsson, Elise A. Lucotte, Fabrizio Mafessoni, Bjarni V. Halldorsson, Mikkel H. Schierup, Moisès Coll Macià, Agnar Helgason, Kari Stefansson, Hakon Jonsson
Publikováno v:
Skov, L, Coll Macià, M, Sveinbjörnsson, G, Mafessoni, F, Lucotte, E A, Einarsdóttir, M S, Jonsson, H, Halldorsson, B, Gudbjartsson, D F, Helgason, A, Schierup, M H & Stefansson, K 2020, ' The nature of Neanderthal introgression revealed by 27,566 Icelandic genomes ', Nature, vol. 582, no. 7810, pp. 78-83 . https://doi.org/10.1038/s41586-020-2225-9
Human evolutionary history is rich with the interbreeding of divergent populations. Most humans outside of Africa trace about 2% of their genomes to admixture from Neanderthals, which occurred 50–60 thousand years ago1. Here we examine the effect o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f02957e905e9bdc23b3effd5180a14ab
https://doi.org/10.1038/s41586-020-2225-9
https://doi.org/10.1038/s41586-020-2225-9
Multiethnic genome-wide association study of differentiated thyroid cancer in the EPITHYR consortium
Autor:
Pierre Laurent-Puig, Yan Ren, Frédérique Rachédi, Pascal Guénel, Sandya Liyanarachchi, Asta Försti, Albert de la Chapelle, Om Kulkarni, Claire Mulot, Huiling He, Federica Gemignani, Julie Guibon, Anne-Valérie Guizard, Fabienne Lesueur, Rossella Elisei, Ausrele Kesminiene, Anthony F. Herzig, Mojgan Karimi, Pierre-Emmanuel Sugier, Thérèse Truong, Delphine Bacq-Daian, Anne-Louise Leutenegger, Constance Xhaard, Daniel F. Comiskey, Celia M Pereda, Evgenia Ostroumova, Florent de Vathaire, Elisabeth Adjadj, Françoise Borson-Chazot, Jean-François Deleuze, Carole Rubino, Anne Boland-Auge, Hauke Thomsen, Elise A. Lucotte, Marie-Christine Boutron-Ruault, Juan J Lence-Anta, Rosa Ortiz, Claire Schvartz
Publikováno v:
International Journal of Cancer
International Journal of Cancer, Wiley, 2021, 148 (12), pp.2935-2946. ⟨10.1002/ijc.33488⟩
International Journal of Cancer, 2021, 148 (12), pp.2935-2946. ⟨10.1002/ijc.33488⟩
International Journal of Cancer, Wiley, 2021, 148 (12), pp.2935-2946. ⟨10.1002/ijc.33488⟩
International Journal of Cancer, 2021, 148 (12), pp.2935-2946. ⟨10.1002/ijc.33488⟩
Incidence of differentiated thyroid carcinoma (DTC) varies considerably between ethnic groups, with particularly high incidence rates in Pacific Islanders. Here, we conducted a genome-wide association study (GWAS) involving 1,554 cases/1,973 controls
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fce6416820f02c763882048815b64fc0
https://hdl.handle.net/11568/1105339
https://hdl.handle.net/11568/1105339
Autor:
Claude Bhérer, Thomas Bataillon, Bruno Toupance, Clara Albiñana, Romain Laurent, Elise A. Lucotte
Sex dimorphisms are widespread in animals and plants, for morphological as well as physiological traits. Understanding the genetic basis of sex dimorphism and its evolution is crucial for understanding biological differences between the sexes. Geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06c2c923f4b7beff2f174d4ea759959e
https://doi.org/10.1101/2020.09.11.293191
https://doi.org/10.1101/2020.09.11.293191
Autor:
Laurits, Skov, Moisès, Coll Macià, Garðar, Sveinbjörnsson, Fabrizio, Mafessoni, Elise A, Lucotte, Margret S, Einarsdóttir, Hakon, Jonsson, Bjarni, Halldorsson, Daniel F, Gudbjartsson, Agnar, Helgason, Mikkel Heide, Schierup, Kari, Stefansson
Publikováno v:
Nature. 582(7810)
Human evolutionary history is rich with the interbreeding of divergent populations. Most humans outside of Africa trace about 2% of their genomes to admixture from Neanderthals, which occurred 50-60 thousand years ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::51ce39c420b180d74a636decddd6320d
https://pubmed.ncbi.nlm.nih.gov/32494067
https://pubmed.ncbi.nlm.nih.gov/32494067
Autor:
David Castellano, Mikkel H. Schierup, Laurits Skov, Thomas Mailund, Kasper Munch, Maria Izabel A. Cavassim, Elise A. Lucotte, Moisès Coll Macià
The X chromosome in non-African populations has less diversity and less Neanderthal introgression than expected. We analyzed X chromosome diversity across the globe and discovered seventeen chromosomal regions, where haplotypes of several hundred kil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f0b3c8121845c0db56bcd4f12f502b
Publikováno v:
Genome Biology and Evolution
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2016, 8 (5), pp.1489-1500. ⟨10.1093/gbe/evw090⟩
Lucotte, E A, Laurent, R, Heyer, E, Segurel, L & Toupance, B 2016, ' Detection of Allelic Frequency Differences between the Sexes in Humans : A Signature of Sexually Antagonistic Selection ', Genome Biology and Evolution, vol. 8, no. 5, pp. 1489-1500 . https://doi.org/10.1093/gbe/evw090
Genome Biology and Evolution, Society for Molecular Biology and Evolution, 2016, 8 (5), pp.1489-1500. ⟨10.1093/gbe/evw090⟩
Lucotte, E A, Laurent, R, Heyer, E, Segurel, L & Toupance, B 2016, ' Detection of Allelic Frequency Differences between the Sexes in Humans : A Signature of Sexually Antagonistic Selection ', Genome Biology and Evolution, vol. 8, no. 5, pp. 1489-1500 . https://doi.org/10.1093/gbe/evw090
International audience; Sexually antagonistic (SA) selection, a form of selection that can occur when both sexes have different fitness optima for a trait, is a major force shaping the evolution of organisms. A seminal model developed by Rice (Rice W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b78cc2fd220c2fd4d750506c408f783d
https://doi.org/10.1093/gbe/evw090
https://doi.org/10.1093/gbe/evw090
Autor:
Elise A. Lucotte, Pascal Guénel, Thérèse Truong, E. Ostroumovae, M. Boutron, Anne Boland, Pierre-Emmanuel Sugier, Arnaud Lefranc, Benoit Liquet, F. de Vathaire, Jean-François Deleuze
Publikováno v:
Revue d'Épidémiologie et de Santé Publique. 68:S140
Thyroid and breast cancers share a lot of similarities in their biology: both are more frequent in women and are influenced by hormonal and reproductive factors. Moreover, individuals diagnosed with breast cancer are more likely to develop thyroid ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fb6580d94405db5e1fd1560489d5e33
https://doi.org/10.1016/j.respe.2020.03.081
https://doi.org/10.1016/j.respe.2020.03.081
Ampliconic genes are good candidates for speciation genes: they are testis-expressed, multicopy and localized on sex chromosomes. Moreover, copy number variation in a specific ampliconic gene pair (SlxandSly) is involved in hybrid incompatibilities b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc718426f35f1b9097810f4872702450
https://doi.org/10.1101/228841
https://doi.org/10.1101/228841