Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Elisaveta E, Genrikhs"'
Publikováno v:
Antioxidants, Vol 8, Iss 5, p 124 (2019)
The aim of this article is to review the publications describing the use of mitochondria-targeted antioxidant therapy after traumatic brain injury (TBI). Recent works demonstrated that mitochondria-targeted antioxidants are very effective in reducing
Externí odkaz:
https://doaj.org/article/4085fe667dc14ce0ad402e7b09cc4092
Publikováno v:
Reviews in the Neurosciences. 31:233-243
The disruption of homeostasis of zinc (Zn2+) and copper (Cu2+) ions in the central nervous system is involved in the pathogenesis of many neurodegenerative diseases, such as amyotrophic lateral sclerosis, Wilson’s, Creutzfeldt-Jakob, Parkinson’s,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ba3a9f408c24bfc5f7ff5b19074deaf
https://doi.org/10.1515/revneuro-2019-0052
https://doi.org/10.1515/revneuro-2019-0052
Autor:
Elisaveta E. Genrikhs, Svetlana Novikova, Elena V. Stelmashook, D. N. Voronkov, Yuliya A. Glibka, Vladimir P. Skulachev, Nickolay K. Isaev, Olga P. Alexandrova
Publikováno v:
Brain Research Bulletin. 148:100-108
The protective effect of SkQR1, a mitochondria-targeted antioxidant, was investigated on the model of focal one-sided traumatic brain injury (TBI) of the sensorimotor cortex region from 1 to 7 days after the injury. TBI caused a reliable disruption o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa07861067fe47ec1c19585e5c2c38c
https://doi.org/10.1016/j.brainresbull.2019.03.011
https://doi.org/10.1016/j.brainresbull.2019.03.011
Publikováno v:
Reviews in the Neurosciences. 29:233-240
One of the approaches to the research of the problem of aging is the study of genetic pathologies leading to accelerated aging, such as the Hutchinson-Gilford progeria syndrome, Werner syndrome, and Down syndrome. Probably, this approach can be used
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a87ae2f36771283ca0ab0f248895ec
https://doi.org/10.1515/revneuro-2017-0051
https://doi.org/10.1515/revneuro-2017-0051
Autor:
Elisaveta E. Genrikhs, M. R. Kapkaeva, Nickolay K. Isaev, Elena V. Stelmashook, Svetlana Avilkina, S. A. Golyshev, Olga P. Alexandrova
Publikováno v:
Toxicology. 393:1-8
Cadmium is a highly toxic heavy metal that is capable of accumulating in the body via direct exposure or through the alimentary and respiratory tract, leading to neurodegeneration. In this article, we show that the application of CdCl2 (0.001-0.005mM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::beeaa8760ea7f60cafd865662ae8277d
https://doi.org/10.1016/j.tox.2017.10.017
https://doi.org/10.1016/j.tox.2017.10.017
Autor:
Vladimir G. Skrebitsky, Leonid G. Khaspekov, Olga V. Popova, Elena V. Stelmashook, Elisaveta E. Genrikhs, P D Rogozin, M. R. Kapkaeva, Nickolay K. Isaev, R. V. Kondratenko
Publikováno v:
Experimental and Toxicologic Pathology. 69:259-264
Copper (Cu2+) is an essential metal presented in the mammalian brain and released from synaptic vesicles following neuronal depolarization. However, the disturbance of Cu2+ homeostasis results in neurotoxicity. In our study we performed for the first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e23cb42ed57560e548e42b7aa9f24874
https://doi.org/10.1016/j.etp.2017.01.011
https://doi.org/10.1016/j.etp.2017.01.011
Publikováno v:
Antioxidants
Antioxidants, Vol 8, Iss 5, p 124 (2019)
Antioxidants, Vol 8, Iss 5, p 124 (2019)
The aim of this article is to review the publications describing the use of mitochondria-targeted antioxidant therapy after traumatic brain injury (TBI). Recent works demonstrated that mitochondria-targeted antioxidants are very effective in reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efd81caea4e6133fc80a84c8c5908135
https://pubmed.ncbi.nlm.nih.gov/31071926
https://pubmed.ncbi.nlm.nih.gov/31071926
Autor:
Elena V. Stelmashook, Elisaveta E. Genrikhs, Elena A. Zelenova, O. P. Aleksandrova, Nickolay K. Isaev
Publikováno v:
Toxicology Letters. :29-34
Copper chloride (0.01mM, 2h) did not have significant influence on the survival of cerebellar granule neurons (CGNs) incubated in balanced salt solution. However, CuCl2 caused severe neuronal damage by glucose deprivation (GD). The glutamate NMDA-rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f007af67a402ca4582cd93aa7a26ae0
https://doi.org/10.1016/j.toxlet.2016.04.002
https://doi.org/10.1016/j.toxlet.2016.04.002
Publikováno v:
Reviews in the neurosciencesReferences. 30(6)
Human aging affects the entire organism, but aging of the brain must undoubtedly be different from that of all other organs, as neurons are highly differentiated postmitotic cells, for the majority of which the lifespan in the postnatal period is equ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::270444373089229b2839bc58350d091c
https://pubmed.ncbi.nlm.nih.gov/30763272
https://pubmed.ncbi.nlm.nih.gov/30763272
Autor:
M. R. Kapkaeva, Elisaveta E. Genrikhs, Elena V. Stelmashook, Nickolay K. Isaev, D. N. Voronkov
Publikováno v:
Toxicology and applied pharmacology. 348
Streptozotocin (STZ) is a glucosamine-nitrosourea compound that is particularly toxic to the insulin-producing beta-cells of the pancreas in mammals; it is used for experimental simulation of sporadic Alzheimer's disease by means of intracerebroventr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8abba50e9d8448cae4272ed78737bca
https://pubmed.ncbi.nlm.nih.gov/29684395
https://pubmed.ncbi.nlm.nih.gov/29684395