Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice

Autor: Brett H. Graham, Tamas Kozicz, Bram Geenen, Maximilian Wiesmann, Elisavet Vasileiou, Jeroen Schoorl, Vivienne Verweij, Tim L. Emmerzaal, Richard J. Rodenburg, Monica Roelofs, Yara Hendriksen, Martijn Arts, Graeme Preston, Femke Grüter, Eva Morava, Eva Klimars, Corné de Groot, Taraka R. Donti, Renske de Veer

Publikováno v: Translational Psychiatry
Translational Psychiatry, 10, 1
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry, 10

Mitochondria play a critical role in bioenergetics, enabling stress adaptation, and therefore, are central in biological stress responses and stress-related complex psychopathologies. To investigate the effect of mitochondrial dysfunction on the stre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7646711746dd5a49bd6e2a6f658c56
https://doi.org/10.1038/s41398-020-0858-y