Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Elisavet PREZA"'
Autor:
Evangelos Asprogerakas, Elisavet PREZA
Publikováno v:
European Journal of Spatial Development, Vol 19, Iss 6 (2022)
The need for a thorough comprehension and integration into the planning practice of the spatial features of European policies has recently emerged and has been reinforced. The recognition in the Treaty of Lisbon of the territorial cohesion as being t
Externí odkaz:
https://doaj.org/article/05d2036125df4244a810260bf75772de
Autor:
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W David Wilson, David W Boykin, Henrik Zetterberg, Linda Partridge, Selina Wray, Gary Parkinson, Stephen Neidle, Rickie Patani, Pietro Fratta, Adrian M Isaacs
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 22-31 (2017)
Abstract Intronic GGGGCC repeat expansions in C9orf72 are the most common known cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), which are characterised by degeneration of cortical and motor neurons, respectively. Repea
Externí odkaz:
https://doaj.org/article/1f8b61ee6cea4757929c90eeb5c2d015
Autor:
Claire E. Hall, Zhi Yao, Minee Choi, Giulia E. Tyzack, Andrea Serio, Raphaelle Luisier, Jasmine Harley, Elisavet Preza, Charlie Arber, Sarah J. Crisp, P. Marc D. Watson, Dimitri M. Kullmann, Andrey Y. Abramov, Selina Wray, Russell Burley, Samantha H.Y. Loh, L. Miguel Martins, Molly M. Stevens, Nicholas M. Luscombe, Christopher R. Sibley, Andras Lakatos, Jernej Ule, Sonia Gandhi, Rickie Patani
Publikováno v:
Cell Reports, Vol 19, Iss 9, Pp 1739-1749 (2017)
Motor neurons (MNs) and astrocytes (ACs) are implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS), but their interaction and the sequence of molecular events leading to MN death remain unresolved. Here, we optimized directed differen
Externí odkaz:
https://doaj.org/article/550ea2af177d49298d42a25f23b48e54
Autor:
Charles Arber, Plamena R Angelova, Sarah Wiethoff, Yugo Tsuchiya, Francesca Mazzacuva, Elisavet Preza, Kailash P Bhatia, Kevin Mills, Ivan Gout, Andrey Y Abramov, John Hardy, James A Duce, Henry Houlden, Selina Wray
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184104 (2017)
Mutations in PANK2 lead to neurodegeneration with brain iron accumulation. PANK2 has a role in the biosynthesis of coenzyme A (CoA) from dietary vitamin B5, but the neuropathological mechanism and reasons for iron accumulation remain unknown. In this
Externí odkaz:
https://doaj.org/article/f5f6c31baff54e20bd2c981bf542ab13
Autor:
Patricia Gomez‐Suaga, Gábor M. Mórotz, Andrea Markovinovic, Sandra M. Martín‐Guerrero, Elisavet Preza, Natalia Arias, Keith Mayl, Afra Aabdien, Vesela Gesheva, Agnes Nishimura, Ambra Annibali, Younbok Lee, Jacqueline C. Mitchell, Selina Wray, Christopher Shaw, Wendy Noble, Christopher C. J. Miller
Publikováno v:
Gomez Suaga, P, Morotz, G, Markovinovic, A, Martin Guerrero, S, Preza, E, Arias Del Castillo, N, Mayl, K, Aabdien, A, Gesheva, V, Nishimura, A, Annibali, A, Lee, Y, Mitchell, J, Wray, S, Shaw, C, Noble, W & Miller, C 2022, ' Disruption of ER-mitochondria tethering and signalling in C9orf72-associated amyotrophic lateral sclerosis and frontotemporal dementia ', AGING CELL, vol. 21, no. 2, e13549 . https://doi.org/10.1111/acel.13549
Hexanucleotide repeat expansions in C9orf72 are the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The mechanisms by which the expansions cause disease are not properly understood but a favoured r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87469f549ade5e5a926eca0967b2b02d
https://pubmed.ncbi.nlm.nih.gov/35026048
https://pubmed.ncbi.nlm.nih.gov/35026048
Autor:
Georgie Lines, Charles Arber, Elisavet Preza, Claire Alexandra Leckey, Natura Myeku, Jackie M. Casey, Michael Perkinton, Selina Wray
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec45cd072dc3614880840a83247421fe
https://doi.org/10.1002/alz.058308
https://doi.org/10.1002/alz.058308
Autor:
Filipa Almeida, Kavitha Siva, Oscar G. Wilkins, Gurvir S. Virdi, Warren Emmett, Elisavet Preza, Michela A. Denti, Jernej Ule, Claudia Manzoni, Alessandro Quattrone, Daniah Trabzuni, Victoria Kay, Mina Ryten, Thomas T. Warner, Roberto Simone, Jamie S. Mitchell, Natalia Barahona-Torres, Demis A. Kia, Per Svenningsson, Mazdak Ehteramyan, Andrew J. Lees, Raffaele Ferrari, Angelika Modelska, Geshanthi Hondhamuni, Jasmine Harley, Rohan de Silva, Vincent Plagnol, Rickie Patani, Alan Pittman, Justyna Zareba-Paslawska, John Hardy, Faiza Javad, Paola Zuccotti, Selina Wray
Publikováno v:
Nature
The human genome expresses thousands of natural antisense transcripts (NAT) that can regulate epigenetic state, transcription, RNA stability or translation of their overlapping genes1,2. Here we describe MAPT-AS1, a brain-enriched NAT that is conserv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d272b40dfe02a5f8381bb307045a35b
https://openaccess.sgul.ac.uk/id/eprint/113282/1/Simone2021_2016-04-05263D_text-Figures_final.pdf
https://openaccess.sgul.ac.uk/id/eprint/113282/1/Simone2021_2016-04-05263D_text-Figures_final.pdf
Autor:
Selina Wray, Matthew Self, NINDS Parkinson's Disease iPSC Consortium, NINDS Huntington's Disease iPSC Consortium, NINDS ALS iPSC Consortium, Patrick A Lewis, Jan-Willem Taanman, Natalie S Ryan, Colin J Mahoney, Yuying Liang, Michael J Devine, Una-Marie Sheerin, Henry Houlden, Huw R Morris, Daniel Healy, Jose-Felix Marti-Masso, Elisavet Preza, Suzanne Barker, Margaret Sutherland, Roderick A Corriveau, Michael D'Andrea, Anthony H V Schapira, Ryan J Uitti, Mark Guttman, Grzegorz Opala, Barbara Jasinska-Myga, Andreas Puschmann, Christer Nilsson, Alberto J Espay, Jaroslaw Slawek, Ludwig Gutmann, Bradley F Boeve, Kevin Boylan, A Jon Stoessl, Owen A Ross, Nicholas J Maragakis, Jay Van Gerpen, Melissa Gerstenhaber, Katrina Gwinn, Ted M Dawson, Ole Isacson, Karen S Marder, Lorraine N Clark, Serge E Przedborski, Steven Finkbeiner, Jeffrey D Rothstein, Zbigniew K Wszolek, Martin N Rossor, John Hardy
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43099 (2012)
Our understanding of the molecular mechanisms of many neurological disorders has been greatly enhanced by the discovery of mutations in genes linked to familial forms of these diseases. These have facilitated the generation of cell and animal models
Externí odkaz:
https://doaj.org/article/9a35e1d7ec9b460c9b9c8d8637a681ec
Impaired Bioenergetics in Mutant Mitochondrial DNA Determines Cell Fate During Seizure-Like Activity
Publikováno v:
Molecular Neurobiology. 56:321-334
Mutations in genes affecting mitochondrial proteins are increasingly recognised in patients with epilepsy, but the factors determining cell fate during seizure activity in these mutations remain unknown. Fluorescent dye imaging techniques were applie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e437bbf559d87a73df75b01e8dcba41
https://doi.org/10.1007/s12035-018-1078-9
https://doi.org/10.1007/s12035-018-1078-9
Autor:
Roberto Simone, Rubika Balendra, Thomas G Moens, Elisavet Preza, Katherine M Wilson, Amanda Heslegrave, Nathan S Woodling, Teresa Niccoli, Javier Gilbert‐Jaramillo, Samir Abdelkarim, Emma L Clayton, Mica Clarke, Marie‐Therese Konrad, Andrew J Nicoll, Jamie S Mitchell, Andrea Calvo, Adriano Chio, Henry Houlden, James M Polke, Mohamed A Ismail, Chad E Stephens, Tam Vo, Abdelbasset A Farahat, W D
Publikováno v:
EMBO Molecular Medicine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::00cb48e5b21aae38db11d8b7fa40305a