Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Elisabetta Visentin"'
Autor:
Eleonora Pedrazzoli, Michele Demozzi, Elisabetta Visentin, Matteo Ciciani, Ilaria Bonuzzi, Laura Pezzè, Lorenzo Lucchetta, Giulia Maule, Simone Amistadi, Federica Esposito, Mariangela Lupo, Annarita Miccio, Alberto Auricchio, Antonio Casini, Nicola Segata, Anna Cereseto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract The expansion of the CRISPR-Cas toolbox is highly needed to accelerate the development of therapies for genetic diseases. Here, through the interrogation of a massively expanded repository of metagenome-assembled genomes, mostly from human m
Externí odkaz:
https://doaj.org/article/b6397b430d9d4dcb8e5d106fca4eda64
Autor:
Matteo Ciciani, Michele Demozzi, Eleonora Pedrazzoli, Elisabetta Visentin, Laura Pezzè, Lorenzo Federico Signorini, Aitor Blanco-Miguez, Moreno Zolfo, Francesco Asnicar, Antonio Casini, Anna Cereseto, Nicola Segata
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Cas9 proteins require a target-adjacent sequence, the PAM, in order to cleave DNA. Here the authors develop a pipeline to accurately predict PAM sequences in order to facilitate the identification of Cas9s targeting specific sequences, including muta
Externí odkaz:
https://doaj.org/article/3d56361b416945b4a632eddfa8cab3d7
Autor:
Matteo Ciciani, Michele Demozzi, Eleonora Pedrazzoli, Elisabetta Visentin, Laura Pezzè, Lorenzo Signorini, Aitor Blanco-Míguez, Moreno Zolfo, Francesco Asnicar, Antonio Casini, Nicola Segata, Anna Cereseto
The identification of the protospacer adjacent motif (PAM) sequences of Cas9 nucleases is crucial for their exploitation as genome editing tools. Here we interrogated a massively expanded dataset of metagenome and virome assemblies for accurate and c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84004eb468b2acc61dc03d3393df2384
https://doi.org/10.21203/rs.3.rs-1652795/v1
https://doi.org/10.21203/rs.3.rs-1652795/v1
