Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Elisabetta Tronci"'
Autor:
Silvia Fanni, Simona Scheggi, Francesca Rossi, Elisabetta Tronci, Francesco Traccis, Roberto Stancampiano, Maria Graziella De Montis, Paola Devoto, Carla Gambarana, Marco Bortolato, Roberto Frau, Manolo Carta
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 120-130 (2019)
Although 1-3,4-dihydroxyphenylalanine (L-DOPA) is the mainstay therapy for treating Parkinson's disease (PD), its long-term administration is accompanied by the development of motor complications, particularly L-DOPA induced dyskinesia (LID), that dr
Externí odkaz:
https://doaj.org/article/19a02c63148348009be80a883732b055
Autor:
Veronica Ghiglieri, Desiree Mineo, Anna Vannelli, Fabrizio Cacace, Maria Mancini, Valentina Pendolino, Francesco Napolitano, Anna di Maio, Manuela Mellone, Jennifer Stanic, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Manolo Carta, Paolo Calabresi, Fabrizio Gardoni, Alessandro Usiello, Barbara Picconi
Publikováno v:
Neurobiology of Disease, Vol 86, Iss , Pp 140-153 (2016)
ABSTRACT: L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesias (LIDs) represent the main side effect of Parkinson's Disease (PD) therapy. Among the various pharmacological targets for novel therapeutic approaches, the serotonergic system represe
Externí odkaz:
https://doaj.org/article/0397c891116e432fb21a3efb279c3141
Autor:
Eunju Shin, Carlo Lisci, Elisabetta Tronci, Camino Fidalgo, Roberto Stancampiano, Anders Björklund, Manolo Carta
Publikováno v:
Neurobiology of Disease, Vol 62, Iss , Pp 233-240 (2014)
Graft-induced dyskinesia (GID) is a serious complication induced by dopamine (DA) cell transplantation in parkinsonian patients. We have recently shown that DA D2 receptor blockade produces striking blockade of dyskinesia induced by amphetamine in gr
Externí odkaz:
https://doaj.org/article/ccbe828bd39b41b18b422cb486e391bc
Autor:
Elisabetta Tronci, Carlo Lisci, Roberto Stancampiano, Camino Fidalgo, Maria Collu, Paola Devoto, Manolo Carta
Publikováno v:
Neurobiology of Disease, Vol 60, Iss , Pp 108-114 (2013)
The serotonin system has recently emerged as an important player in the appearance of l-DOPA-induced dyskinesia (LID) in experimental models of Parkinson's disease, as it provides an unregulated source of l-DOPA-derived dopamine release in the dopami
Externí odkaz:
https://doaj.org/article/65cb9c949d0049cbaa552f3b16529335
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
Transplantation of dopamine- (DA-) rich foetal ventral mesencephalic cells emerged as a promising therapy for Parkinson’s disease (PD), as it allowed significant improvement of motor symptoms in several PD patients in open-label studies. However, d
Externí odkaz:
https://doaj.org/article/113d41db1bd74b67942fd48698bd98b8
Publikováno v:
Parkinson's Disease, Vol 2012 (2012)
L-DOPA, the most effective drug to treat motor symptoms of Parkinson's disease, causes abnormal involuntary movements, limiting its use in advanced stages of the disease. An increasing body of evidence points to the serotonin system as a key player i
Externí odkaz:
https://doaj.org/article/ae1735a293b443628c6142492521435e
Autor:
Marco Bortolato, Francesca Rossi, Maria Graziella De Montis, Paola Devoto, Elisabetta Tronci, Simona Scheggi, Silvia Fanni, Manolo Carta, Carla Gambarana, Roberto Stancampiano, Roberto Frau, Francesco Traccis
Publikováno v:
Neurobiology of Disease, Vol 121, Iss, Pp 120-130 (2019)
Although 1-3,4-dihydroxyphenylalanine (L-DOPA) is the mainstay therapy for treating Parkinson's disease (PD), its long-term administration is accompanied by the development of motor complications, particularly L-DOPA induced dyskinesia (LID), that dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5653e373e872071da6e2b20ee7d94ace
https://doi.org/10.1016/j.nbd.2018.09.018
https://doi.org/10.1016/j.nbd.2018.09.018
Publikováno v:
Clinical Trials In Parkinson's Disease ISBN: 9781071609118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03b6c6feb15beeb1ce61854eb13776e0
https://doi.org/10.1007/978-1-0716-0912-5_2
https://doi.org/10.1007/978-1-0716-0912-5_2
Autor:
Roberto Stancampiano, Francesca Rossi, Romina Vargiu, Ana Muñoz, Anders Björklund, Silvia Fanni, Simona Scheggi, Elisabetta Tronci, Sara Corsi, Manolo Carta, Carla Gambarana, Congiu Ludovica
Background: We recently showed that striatal overexpression of brain derived neurotrophic factor (BDNF) by adeno-associated viral (AAV) vector exacerbated L-DOPA-induced dyskinesia (LID) in 6-OHDA-lesioned rats. An extensive sprouting of striatal ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d65629dd8f9373e3fa9eb89c157c10e
http://hdl.handle.net/11365/1120370
http://hdl.handle.net/11365/1120370
Autor:
Ana Muñoz, Anders Björklund, Camino Fidalgo, Alessandro Usiello, Elisabetta Tronci, Manolo Carta, Francesco Napolitano, Francesca Rossi
Publikováno v:
Experimental Neurology. 297:73-81
In addition to its role in neuronal survival, the brain neurotrophic factor (BDNF) has been shown to influence serotonin transmission and synaptic plasticity, events strongly implicated in the appearance of l-DOPA-induced dyskinesia (LID), a motor co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f158a02bce1c188997047962ca01e2
https://doi.org/10.1016/j.expneurol.2017.07.017
https://doi.org/10.1016/j.expneurol.2017.07.017