Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Elisabetta Mueller"'
Autor:
Narendra Verma, Luce Perie, Carmen Corciulo, Philipp Leucht, Bhama Ramkhelawon, Bruce N. Cronstein, Elisabetta Mueller
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 11, Pp 877-887 (2021)
Abstract Methotrexate (MTX) is widely used for the treatment of rheumatoid arthritis due to its well‐known anti‐inflammatory role in immune cells but its impact on brown and beige adipose tissue biology has not yet been investigated. Here, we pre
Externí odkaz:
https://doaj.org/article/942950ae8a104b6ea83c9fa62a37213b
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100102- (2021)
Forkhead box transcription factors have been shown to be involved in various developmental and differentiation processes. In particular, members of the FoxP family have been previously characterized in depth for their participation in the regulation
Externí odkaz:
https://doaj.org/article/a30217596c954b7e86645c5993545c8a
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 9, Pp 1886-1896 (2014)
Increasing evidence indicates that transcription and alternative splicing are coordinated processes; however, our knowledge of specific factors implicated in both functions during the process of adipocyte differentiation is limited. We have previousl
Externí odkaz:
https://doaj.org/article/4abebb61b2064a2a9decdb7b80bc1b1a
Autor:
Martin Schlegel, Lianne C Shanley, Narendra Verma, Daniel Peled, Jenny Y Yoo, Coen van Solingen, Elisabetta Mueller, Yannick Cyr, Luce Perie, Kathryn J. Moore, Milessa Silva Afonso, Ann Marie Schmidt, Monika Sharma, Emma M Corr
Publikováno v:
Arterioscler Thromb Vasc Biol
Objective:Recent studies have identified key transcriptional regulators of brown adipose tissue (BAT) differentiation and function, but posttranscriptional control of this network by microRNAs remains incompletely understood. MiR-33 critically regula
Publikováno v:
J Biol Chem
Heat shock factor 1 (HSF1) regulates cellular adaptation to challenges such as heat shock and oxidative and proteotoxic stresses. We have recently reported a previously unappreciated role for HSF1 in the regulation of energy metabolism in fat tissues
Publikováno v:
Journal of the Endocrine Society
Zinc finger factors are implicated in a variety of cellular processes, including adipose tissue differentiation and thermogenesis. We have previously demonstrated that zinc finger protein 638 (ZNF638) is a transcriptional coactivator acting as an ear
Publikováno v:
Journal of Lipid Research, Vol 62, Iss, Pp 100102-(2021)
Journal of Lipid Research
Journal of Lipid Research
Forkhead box transcription factors have been shown to be involved in various developmental and differentiation processes. In particular, members of the FoxP family have been previously characterized in depth for their participation in the regulation
Autor:
Narendra Verma, Jian Luo, Jose O. Aleman, Dongmei Wang, Sama Shamloo, Mingwei Guo, Audrey Noguchi, Philipp Leucht, Jin Li, Fei Shen, Michele D. Allen, Anne M Josephson, Lingyan Xu, Xiaodan Ping, Lingyu Li, Xinran Ma, Jin Qiu, Junjie Xiao, Jay Pendse, Elisabetta Mueller, Shiwei Zhang, Danielle A. Springer, Luce Perie, Jian Lu, Zhen-Yu Du, Caizhi Liu
Publikováno v:
Aging Cell
Aging leads to a number of disorders caused by cellular senescence, tissue damage, and organ dysfunction. It has been reported that anti‐inflammatory and insulin‐sensitizing compounds delay, or reverse, the aging process and prevent metabolic dis
Autor:
Richard L. Proia, Narendra Verma, Elisabetta Mueller, Dongmei Wang, Toren Finkel, Oksana Gavrilova, Lingyan Xu, Xinran Ma
Publikováno v:
Aging Cell
Summary It is well established that aging is associated with metabolic dysfunction such as increased adiposity and impaired energy dissipation; however, the transcriptional mechanisms regulating energy balance during late life stages have not yet bee
Autor:
Jie Liu, Elisabetta Mueller, Oksana Gavrilova, Alessia Bagattin, Anna Teresa Alberobello, Xinran Ma, Monica C. Skarulis, Lingyan Xu, Toren Finkel
Publikováno v:
Cell Metabolism. 22(4):695-708
SummaryAltering the balance between energy intake and expenditure is a potential strategy for treating obesity and metabolic syndrome. Nonetheless, despite years of progress in identifying diverse molecular targets, biological-based therapies are lim