Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Elisabetta Monaci"'
Autor:
Francesca Mancini, Elisabetta Monaci, Giuseppe Lofano, Antonina Torre, Marta Bacconi, Simona Tavarini, Chiara Sammicheli, Letizia Arcidiacono, Bruno Galletti, Donatello Laera, Michele Pallaoro, Giovanna Tuscano, Maria Rita Fontana, Giuliano Bensi, Guido Grandi, Silvia Rossi-Paccani, Sandra Nuti, Rino Rappuoli, Ennio De Gregorio, Fabio Bagnoli, Elisabetta Soldaini, Sylvie Bertholet
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147767 (2016)
A rapidly acting, single dose vaccine against Staphylococcus aureus would be highly beneficial for patients scheduled for major surgeries or in intensive care units. Here we show that one immunization with a multicomponent S. aureus candidate vaccine
Externí odkaz:
https://doaj.org/article/6ab3e96e44b344fa8ee5845c6760ebd9
Autor:
Mirela Kuka, Roberta Baronio, Sara Valentini, Elisabetta Monaci, Alessandro Muzzi, Susanna Aprea, Ennio De Gregorio, Ugo D'Oro
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11491 (2010)
BACKGROUND: Pathogen recognition by dendritic cells (DC) is crucial for the initiation of both innate and adaptive immune responses. Activation of Toll-like Receptors (TLRs) by microbial molecular patterns leads to the maturation of DC, which present
Externí odkaz:
https://doaj.org/article/9dfde84ce13040d5b82b316633bdd327
Autor:
Marianna Taccone, Elisabetta Monaci, Anja Seubert, Ruchi Rudraprasad Shah, Mansoor M. Amiji, Derek T. O'Hagan, Alessandra Bonci, Luis Brito
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
Self-emulsification is routinely used for oral delivery of lipophilic drugs in vivo, with the emulsion forming in vivo. We modified this technique to prepare novel oil-in-water emulsions of varying droplet size and composition on bench to enable adju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b631cf8e2e20a29c8c5bf4f17fad8127
http://link.springer.com/article/10.1038/s41598-019-47885-z
http://link.springer.com/article/10.1038/s41598-019-47885-z
Autor:
Erwin Swennen, Rino Rappuoli, Barbara Baudner, Antonina Torre, Roberto Petracca, Luigi Fiaschi, Juliane Bubeck Wardenburg, Naoko Inoshima, Elisabetta Monaci, Sabrina Liberatori, C. Daniela Rinaudo, Cecilia Brettoni, Maria Rita Fontana, Silvia Maccari, Paolo Mariotti, Nicholas Valiante, Silvana Savino, Sarah Nosari, Elena Mori, Vincenzo Nardi-Dei, Bruno Galletti, Elena Cartocci, Marta Bacconi, Ennio De Gregorio, Guido Grandi, Giuseppe Lofano, Ravi Prakash Mishra, Derek T. O'Hagan, Sylvie Bertholet, Nathalie Norais, Olaf Schneewind, Michele Pallaoro, Sara Marchi, Elisabetta Soldaini, Maria Scarselli, Fabio Bagnoli, Silvia Rossi-Paccani, Giuliano Bensi, Paolo Ruggiero, Maria Grazia De Falco
Publikováno v:
Proceedings of the National Academy of Sciences. 112:3680-3685
Both active and passive immunization strategies against Staphylococcus aureus have thus far failed to show efficacy in humans. With the attempt to develop an effective S. aureus vaccine, we selected five conserved antigens known to have different rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14195a9e335b41675321eb3ba865b770
https://doi.org/10.1073/pnas.1424924112
https://doi.org/10.1073/pnas.1424924112
Autor:
Donatello Laera, Maria Rita Fontana, Fabio Bagnoli, Simona Tavarini, Silvia Rossi-Paccani, Giuliano Bensi, Guido Grandi, Francesca Mancini, Sylvie Bertholet, Ennio De Gregorio, Bruno Galletti, Michele Pallaoro, Sandra Nuti, Elisabetta Soldaini, Giuseppe Lofano, Chiara Sammicheli, Giovanna Tuscano, Letizia Arcidiacono, Rino Rappuoli, Elisabetta Monaci, Marta Bacconi, Antonina Torre
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 1, p e0147767 (2016)
PLoS ONE, Vol 11, Iss 1, p e0147767 (2016)
A rapidly acting, single dose vaccine against Staphylococcus aureus would be highly beneficial for patients scheduled for major surgeries or in intensive care units. Here we show that one immunization with a multicomponent S. aureus candidate vaccine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9920a4b58f3464fc50e1289e63cb083
http://europepmc.org/articles/PMC4727907
http://europepmc.org/articles/PMC4727907
Autor:
Simona Tavarini, Sandra Nuti, Alessandro Muzzi, Ennio De Gregorio, Elaine Tritto, Andreas Wack, Isabella Pesce, Elisabetta Monaci
Publikováno v:
Journal of Innate Immunity. 2:144-159
CpG-containing oligodeoxynucleotides are potent mucosal adjuvants and effective as stand-alone treatment of respiratory infections in mice. Although CpG is also used as a type 1 helper immunomodulator in the treatment of asthma and allergic disease,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef76806ed77531ddced4d9c4c686418d
https://doi.org/10.1159/000254948
https://doi.org/10.1159/000254948
Publikováno v:
The Journal of Immunology. 180:5402-5412
Aluminum hydroxide (alum) and the oil-in-water emulsion MF59 are widely used, safe and effective adjuvants, yet their mechanism of action is poorly understood. We assessed the effects of alum and MF59 on human immune cells and found that both induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0f5595d380538b4ea21d20b967fa05
https://doi.org/10.4049/jimmunol.180.8.5402
https://doi.org/10.4049/jimmunol.180.8.5402
Autor:
Elisabetta Monaci, Mariagrazia Pizza, Vega Masignani, Elena Cartocci, Laura Serino, Ann E. Jerse, Rino Rappuoli, Brian T. Mocca, Rosanna Leuzzi, Maria Rita Fontana, Barbara Nesta
Publikováno v:
Molecular Microbiology. 64:1391-1403
Outer membrane protein As (OmpAs) are highly conserved proteins within the Enterobacteriaceae family. OmpA contributes to the maintenance of structural membrane integrity and invasion into mammalian cells. In Escherichia coli K1 OmpA also contributes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33d152eabba9df1e8aca2986b67889de
https://doi.org/10.1111/j.1365-2958.2007.05745.x
https://doi.org/10.1111/j.1365-2958.2007.05745.x
Autor:
Maria Scarselli, Rino Rappuoli, Maria Rita Fontana, Silvana Savino, Gunter Fischer, Laura Serino, Rosanna Leuzzi, Mariagrazia Pizza, Elisabetta Monaci, Annarita Taddei
Publikováno v:
Molecular Microbiology. 58:669-681
Summary Macrophage infectivity potentiators (MIPs) are a family of surface-exposed virulence factors of intracellular microorganisms such as Legionella , Chlamydia and Trypanosoma . These proteins display peptidylprolyl cis / trans isomerase (PPIase)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a68aaafc00b72cd85776f4c2e147a94b
https://doi.org/10.1111/j.1365-2958.2005.04859.x
https://doi.org/10.1111/j.1365-2958.2005.04859.x
Autor:
Luis Brito, Ennio De Gregorio, Susanna Aprea, Samuele Calabrό, Chun Li, Francesco Doro, Sina Bavari, Miller Andrew T, David A. G. Skibinski, Rekha G. Panchal, Donatello Laera, M. Lamine Mbow, Simone Bufali, Ann E. Herman, Ugo D'Oro, Michael P. Cooke, Elaine Tritto, Padma Malyala, Brunella Brunelli, Elisabetta Monaci, Alex Cortez, Gillis R. Otten, Sara Valentini, Travis K. Warren, Christophe M. Filippi, Nicholas Valiante, Yongkai Li, Tom Y.-H. Wu, Bishnu P. Nayak, Manmohan Singh, Elena Caproni, Derek T. O'Hagan
Publikováno v:
Science translational medicine. 6(263)
Adjuvants increase vaccine potency largely by activating innate immunity and promoting inflammation. Limiting the side effects of this inflammation is a major hurdle for adjuvant use in vaccines for humans. It has been difficult to improve on adjuvan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0d1bdbb2ebc009cbc67a1ff4484d95
https://pubmed.ncbi.nlm.nih.gov/25411473
https://pubmed.ncbi.nlm.nih.gov/25411473